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Volume 26, Issue 12
Displaying 1-7 of 7 articles from this issue
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Masashi Takeuchi, Tsuneyo Furukawa, Yoshihiro Kokubo1966 Volume 26 Issue 12 Pages 731-736
Published: December 28, 1966
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (763K) -
Tadayuki Yambe1966 Volume 26 Issue 12 Pages 737-752
Published: December 28, 1966
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSStudies were performed on the pattern of hemolysis and change of fraction of serum protein with the production of erythropoietin in the phenylhydrazine-treated rabbits, and following results were obtained.
1. Hemoglobin concentrations, hematcrit and erythrocyte count showed marked decrease after starting the daily injection of phenylhydrazine and reached to the half level in their value by the fifth day.
Reticulocyte count increased abruptly few days after starting injection.
2. Decrease of albumin and increase of α2- and γ-globulin were seen as the degree of anemia enforced.
3. Efforts were done for obtaining different level of hemoglobin concentration upon exanguination. Increased erythropoietin titer was obtained in 85.7 % of specimens with below 6.5 Gm/dl of hemoglobin concentration. However, elevated erythropoietin was seen in few subjects with those of over 6.5 Gm/dl of hemoglobin.View full abstractDownload PDF (1355K) -
2. On the Immunological Characters of S-type and R-typeKeisuke Miyaji1966 Volume 26 Issue 12 Pages 753-758
Published: December 28, 1966
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSS-type of Z 27, Z 29 and R-type of Z 29 designated by this author were isolated from the strains of Lactobacillus acidophilus and their immunological characters were investigated by precipitation reaction both with so-called carbohydrate-antigen of Lancefield and with ordinary agglutination reaction.
As the result of these experiments, following points were clarified :
1. In precipitation reaction, no particular difference was observed whether the serum and the antigen are in homologous relation or in heterologous one.
Howerer very slight lowering of the titre was observed in the reaction between S-type antigen and R-type serum or between R-type antigen and S-type serum.
2. In agglutination reaction, no particular difference was observed in the titre among different strains of the species and between S-type antigen and R-type serum or R-type antigen and Stype serum.View full abstractDownload PDF (571K) -
Masashi Yamaguchi1966 Volume 26 Issue 12 Pages 759-772
Published: December 28, 1966
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIt is regarded that brain is easily affected by anoxia and various clinical events of neurology and psychiatry are basically connected with the problems of anoxia.
Rat was ligated in right carotid artery and was exposed to nitrous oxide for one hour after the procedure of Levine to result in anoxic-ischemic encephalopathy. P-32 was administered intraperitoneally one hour prior to sacrifice. Brain was excised quickly and divided in bilateral hemispheres. After homogenizing water content, methylene blue reduction activity (M.B.R.A.) and P-32 uptake of each halves were measured.
Increased water content, depressed M.B.R.A. and increased P-32 uptake were observed in the ligated, compared to unligated side, which might suggest the development of cerebral edema supression of aerobic glycolysis and increased permeability of blood-brain barrier to phosphate in ratbrain under to phosphate in rat-brain under the condition of anoxia. P-32 incorporated in the affected side mostly remained in acid-solubee fraction, not in acid-insoluble fraction. These cohanges in anoxia of rat-brain were studied with the lapse of time. M. B. R.A. in the affected side was depressed immediately after the hypoxia ; the increased P-32 uptake and the increased water content did not become apparent for a while. In the early period (6-9 hours elapsed after the hypoxia) these changes were so marked to be regarded as the hydrated or edematous phase. ; in the late period (around hours) they recovered. The water content and the P-32 uptake passed the time of light decreare in the late period as the dehydrated phase.
M.B.R.A, and P-32 uptake hat the close linear relationship to water content, especially in the hydrated phase. These results seemed to mean the course of the supression of aerobic glycolysis, the development of cerebral edema and the increased permeability of blood-brain barrier induced by anoxia.
These results were discussed on cerebral edema, blood-brain barrier and energy metabolism of brain. Further evidences of the changes in the experimental hypoxia of rat brain will be added in my future study.View full abstractDownload PDF (3097K) -
Yasuhide Matsuoka1966 Volume 26 Issue 12 Pages 773-799
Published: December 28, 1966
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe present study was designed to investigate the fetal electrocardiograms on 381 cases of the pregnant women.
The abdominal bipolar lead was used in majority cases, but sometime the direct lead placing one electrode on the fundus of the uterus and the other electrode on the fetal head was applied.
The fetal electrocardiogram started to be obtained in 15 out of 19 cases (78.9 %) as esrly as the first half of the fifth lunar month and 80-100 % of cases were able to record during the 6 th to the latter half of the 7 th lunar month. Then the rate of the cases for recording decreased until the end of the 8 th lunar month and increased to the rate of 93.8-100 % during the period of the 9 th and the 10 th lunar month.
The decrease of heart rate, the prolongation of the QRS interval and the increase of the amplitude of the QRS complex were noted as pregnancy progressing.
According to the direction of QRS complex the fetal electrocardiogram was classified into R pattern and S pattern. The R pattern was observed in 99.3 % of the cases with cephalic presentation and the S pattern in 61.9 % of the cases with breech presentation.
The determination of fetal position was possible using the combination of vertical lead and horizontal lead.
The frequency of various patterns of the QRS complex in the normal cases of with cephalic presentation was as follows : R pattern 51.8%, Rs 22.4%, qR 17.0%, qRs 1.7%, R. S 8.6 %, rS 3.4%, and S 10.3%.
The heart rate decreased upon the fit of labor pains or the administration of pituitary posterior hormones, and increaced by oxygenating the mother. However, these factors did not induce any significant change on the QRS complex.
In the reference to the Rs pattern and rS pattern, these were obtained in 53.8 % of the cases which had asphyxia and indicated the apgar index below 7, and in 24.5 % of the cases with coiling of the cord. These numbers were greater than those in normal cases.
The QRS amplitude useing dinect lead from the fetal head was 1.8-3.5 times compared with the aplitude of leading from the abdominal wall.
The large amount of hydramnions interf erred the recording of fetal electrocardiogram.View full abstractDownload PDF (17064K) -
Susumu Yuto, Minoru Hojyo, Tadashi Mitsuoka, Tadayoshi Hayama1966 Volume 26 Issue 12 Pages 800-807
Published: December 28, 1966
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThirty years old man, was admitted with chief complaint of weakness, slight fever chest pain and backache.
Positive physical findings were only spleenomegaly and marked enlargement of general lymphnodes which grew up gradually to form a mass as large as walnut in size.
A numeral atypical large cell (6-8μ) in the peripheral blood were round or oval, its nucleus was irregular in its form and had a fine structure and from one to three numbers of nuleolei in each. These cells were assumed to belong to the cells of lympatic system based on the fact that cystoplasma was stained basophilic, showed positive PAS staining and negative peroxidase reaction with mcJunkin's method.
This patient, diagnosed as leukemic lymphosarcomatosis on the basis of above observations, expired appoximately 6 months later when atypical cells appeared in 95 per cent in his peripheral blood.View full abstractDownload PDF (4470K) -
Masakazu Kawasumi, Keizo Takahashi, Yoshio Igarashi, Michi Matsumoto, ...1966 Volume 26 Issue 12 Pages 808-813
Published: December 28, 1966
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSSodium γ-Hydroxybutyrate (OBA) was used as premedicants and the clinical effects were studied. Patients in relatively good risk, aged between 13 and 69, who had no association of illness, were selected for study at random. These patients were divided into three groups. The first group, the second group and the third group were given OBA 10-20 milligram per kilogram, OBA 66 milligram per kilogram and the placebo respectively. Each drugs were administered orally 1 1/2 hour prior to anesthesia induction and other no drugs combined. The effects were as follows;
(1) In the first group, sedative effects were not evident. But 91.2 per cent in the second group were good sedated and there was no effect in the third group.
(2) In the second group, patients exhibited many side effects such as exhausted feeling, heaviness in head, vertigo, nausea, headache, salivary secretion etc. It seemed that these side effects were mitigated by the combination with other drugs. For example, parasympathomimetic action was ameliorated with addition of belladonna.
(3) There were no significant changes in blood pressure, pulse rate, ECG and minute volume.
(4) The EEG pattern in subjects administering 66 milligram per kilogram of OBA resembled to those with natural sleeping pattern.View full abstractDownload PDF (2854K)
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