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Volume 36 (1976)
- Issue 5-6 Pages 375-
- Issue 4 Pages 275-
- Issue 3 Pages 191-
- Issue 2 Pages 113-
- Issue 1 Pages 1-
Volume 36, Issue 5-6
Displaying 1-11 of 11 articles from this issue
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[in Japanese]1976 Volume 36 Issue 5-6 Pages 375-379
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
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[in Japanese]1976 Volume 36 Issue 5-6 Pages 381-383
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
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Koji Sakamoto, Hajime Yasuhara, Takako Kasahara, Tadasuke Nishimura, T ...1976 Volume 36 Issue 5-6 Pages 385-391
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSLiver function was examined in gastric ulcer patients under anesthesia who underwent gastric resection (Billroth's method) and who showed good general conditions by modified neuroleptoanesthesia (NLA) using Droperidol and Pentazocine.
Futher, liver function and liver tissue were examined in rabbits administered Droperidol and Pentazocine intravenously, and results obtained were compared with those in man.
Biochemically, there was noted a decline in serum total protein of man following anesthesia. Besides, no marked change in liver function was observed in both man and rabbit.
Microscopically, changes were noted up to 6 hours after anesthesia. On 24 hours, there was a tendency to recovery microscopically, but changes were still observable electron microscopically.
The effect of Droperidol and Pentazocine on the liver disappears with the lapse of time ; however, it is possible that these drugs will cause a transient change in liver cells.View full abstractDownload PDF (5906K) -
Yutaka Masuda1976 Volume 36 Issue 5-6 Pages 393-403
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA total of 488 total spinal blocks was performed in 66 patients. The indications of the block are cervico-omo-brachial syndrome, whiplash injury, headache, causalgia, phantom limb pain, herpes zoster, postherpetic neuralgia and other diseases. On an average, seven times of the block was given to each patient, maximum was 35 times. Remarkable or satisfactory results were obtained in 54 patients (81.1%), but no improvement in 12 patients. Gas chromatographic analysis of mepivacaine in venous plasma before, during and after the block was carried out in ten patients. The peak plasma concentration of mepivacaind was detected after 60 minutes of the injection of 300 mg into subarachnoid space, it was 2.15 μg/ml. On the other hand, it needed 120 minutes to reach the peak level, 2.40 μg/ml, in the groupe who received 450 mg of mepivacaine. During the block, any significant changes in blood pressure, pulse rate, and ECG were never observed. EEG findings showed slow wave in almost all cases, but one showed seizure pattern.View full abstractDownload PDF (5658K) -
Katsuya Nakagawa, Ryohey Koide, Mieko Ikeno, Rittoh Matsui, Shuji Aman ...1976 Volume 36 Issue 5-6 Pages 405-410
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMonoamine oxidase (MAO) activities in serum, kidney, brain and liver from rabbit, dog, rat and mouse were assayed with benzylamine as substrate using McEwen's assay procedure. The original McEwen's method was modified to fit for measurement of MAO activities not only in serum but also in the other various tissues. The modification was accomplished by using a large tube with 2.5 cm of diameter for reaction tube and by shaking it with 100 strokes per minute during the reaction. By this new procedure, it became possible to compare the MAO activity in serum with those in the other tissues. For example, it was found that MAO activities in kideny, brain and liver from rabbit were 101, 21 and 259 times, respectively, of that in serum. While, the MAO activities in serum from rat and mouse were not detected by this method. It became possible to measure MAO activity in the extreme small amount of liver homogenate, such as 0.3 mg of rabbit liver. MAO activities in serum, brain, kidney and liver from rabbit were inhibited completely by pheniprazine (1×10-5 M), but that in serum was not inhibited by pargyline (1×10-5 M) whereas those in kidney, brain and liver were inhibited. Moreover, MAO in serum was inhibited by harmaline (1×10-5 M) whereas those in brain, kidney and liver were not. KCN (10-2M) inhibited MAO in serum and kidney but not inhibited those in brain and liver. These results are suggesting that there are multiple forms of MAO in organs.View full abstractDownload PDF (638K) -
Sohei Asano1976 Volume 36 Issue 5-6 Pages 411-417
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESS1. Changes in concentrations of plasma triglyceride and FFA were investigated in the starved rabbits, in which cobalt chloride was administered once a day for eight consecutive days and compared with those of starved rabbits. Concentration of plasma triglyceride in cobalt-treated animals began to increase after injection and rose to the level of 600-700 mg/dl on the average after 120 hr. In the starved control rabbits, plasma triglyceride changed within the normal range and rose to the level over 100 mg/dl after 144 hr. Plasma FFA concentration in cobalt-treated rabbits was elevated rapidly after injection and fluctuated thereafter in the range of 300-500 μEq/L, while in the starved controls it changed in parallel with that of the former, but remained higher throughout the experiment
2. Starved rabbits were injected with cobalt chloride once a day for three days and following items were compared with normal fed or starved control rabbits.
a. Cobalot chloride administration induced six times higher plasma triglyceride, and twice higher hepatic triglyceride than those of starved animals, while plasma FFA remained in lower level than that of starved control
b. Plasma free glycerol concentration was increased in cobalt-treated animals, but no significant decrease could be observed in starved control.
c. Hepatic α-glycerophosphate content showed no change either in starved or in cobalt-treated animals.
d. In cobalt-treated animals, blood glucose level was slightly higher, but no significant change could be seen in blood lactate and pyruvate concentration, as compared with those of starved control and normal fed animals
e. Hepatic glucose fluctuated in parallel with blood glucose. Heptic lactate arranged in order of decreasing content was : normal feed, starved control, and cobalt-treated, whereas hepatic pyruvate was of the reversed order as the former.View full abstractDownload PDF (759K) -
Toru EGASHIRA, Ryohey KOIDE, Mieko IKENO, Yasuo AWAYA, Hideyasu AOKI, ...1976 Volume 36 Issue 5-6 Pages 419-424
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe effects of nitrites and nitrates on MAO activities from liver, brain, kidney and heart were studied with tyramine and benzylamine as substrate. MAO activity was determined manometrically.
With tyramine as substrate, the MAO activities of brain, kidney and heart increased with increase in the concentrations of sodium nitrite and potassium nitrite, but the activity of liver did not change. Amylnitrite inhibited the activities of liver, brain and kidney strongly and that of heart slightly.
With benzylamine as substrate, the MAO activities of liver and heart increased markedly, that of brain increased slightly and that of kidney decreased with increase in the concentration of sodium nitrite.
With benzylamine as substrate the activities from the four organs increased on addition of potassium nitrite. The activities of liver, brain and kidney decreased gradually with increase in the concentration of amylnitrite, but that of heat increased.
Thus the MAO activities from brain, kidney and heart were increased by all the nitrites tested, except amylnitrite, and were inhibited by nitrates.View full abstractDownload PDF (591K) -
Hidenori Ota, Toshio Morohoshi, Umemaru Ueda, Kazuko Hata, Keinosuke U ...1976 Volume 36 Issue 5-6 Pages 425-428
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSFour-month-old female baby died of severe “infantile lobar emphysema” observed in right. upper, right, lower and left. upper lobe of the lung was examined histopathologically. The present case was classified into the type of “Defective cartilage group” (according to Stovin), “Deficiency of bronchial cartilage” (Leape et al.) and “Bronchial cartilagenous dysplasia” (Hendern) .View full abstractDownload PDF (3761K) -
Shigeru Tomoyasu, Haruo Takeuchi, Naokazu Nunoue, Morimasa Ishibashi, ...1976 Volume 36 Issue 5-6 Pages 429-435
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA 29 year-old single man, worker, was admitted to this hospital because of emaciation. He had lost 28 kg in weight during last three years. On admission, his height was 181 cm and weight was 45 kg. The lung and heart were normal. No enlargement of lymphnodes were found. Neurological findings were normal except for horizontal nystagmus. X-ray films of the skull revealed calcification of pineal body and no abnormality of sella turcica. A lumbar puncture yealded clear cerebrospinal fluid under normal pressure. Cell count was 3 per cubic millimeter. The protein was 87 mg per 100 ml and the glucose 77 mg per 100 ml. Metopyron test showed a dysfunction of hypophysis. Encephaloangiogram disclosed the upperward deviation of middle cerebral artery. OKP test disclosed diencephalic tumor. On 135 th hospital day, he fell in coma and died. The post-mortemn examination of the brain showed a tumor of corpus collasum and frontal lobe. The tumor extended to the 3 rd ventricle, 4 th ventricle, pons, cerebellum and medulla oblongata. However, hypothalamus and hypophysis were not involved. We suspected that cause of emaciation may be related to the involvement of the 3 rd ventricle basis.View full abstractDownload PDF (3837K) -
Hidemasa Seki, Yoshiaki Mori, Hideyo Miyaoka1976 Volume 36 Issue 5-6 Pages 437-440
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA big phymas was observed from tubersity of tibia to prepatellar region and it was extripated. This phyma was formed by connecting prepatellar bursa and it was considered from anamnesis of trauma, that the two bursas were connected secondarly and became giantic.View full abstractDownload PDF (4544K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1976 Volume 36 Issue 5-6 Pages 465-469
Published: December 28, 1976
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (597K)
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