Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Search
Advanced search
OR
Browse
Search
Volume 71, Issue 6
Displaying 1-19 of 19 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
Feature Articles: Syncope up to Date
Graphic
Original
  • DERMOSCPIC EVALUATION OF NORMAL CHEEK SKIN PIGMENTATION
    Hitoshi NEMOTO, Noriyoshi SUMIYA, Yoshinori ITO, Naohiro KIMURA
    2011 Volume 71 Issue 6 Pages 588-595
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.588
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Empirical evidence has revealed that skin pigmentation increases with age. A few objective studies have evaluated the relationship between pigmentation and aging. We analyzed the pigmentation of the normal cheek skin using a dermoscope. Subjects were 80 Japanese, stratified by sex and age. Images of their cheek skin were obtained bilaterally at 50× magnification using a dermoscope. The pigmentation density was converted into L*a*b color system using software, TOCOL photocolor tool. The area of the pigmentation was measured using an image analysis software, Image J. Statistical analysis was performed using software JMP (SAS Co.). A total of 160 were obtained. Although the skin looked normal by naked eye obsevation, perifolliclular pigmentation was found on dermscopy. The pigmentation showed a tendency to first occur in the perifolliclular region at 4 or 5 years of age and extend to the surrounding areas with increasing age. Darkening of the pigmentation tended to constantly increase with increasing age until 40 years of age (P＜0.0001). However, at above 60 years of age, darkening of the pigmentation tended to be decrease in males, and darkening of the pigmentation tended to be increase in females. The pigmented area tended to constantly increase with increasing age (P＜0.0001). Thus, differences were observed between males and females in the density and area of pigmentation; males had darker and larger area of pigmentation than females.
    View full abstract
    Download PDF (772K)
  • RESEARCH ON THE RELATIONSHIP BETWEEN DAYS FROM ONSET TO TRANSFER AND PROGNOSIS
    Hiroshi INABA, Humihito KASAI, Izumi KUNIYOSHI, Shinsuke IIJIMA, Mizut ...
    2011 Volume 71 Issue 6 Pages 596-601
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.596
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    (Purpose and methods) The length of hospital stay after onset/injury/ to transfer (the acute period of admission from the onset [of illness]/ injury/ surgery) through to admission to the convalescent rehabilitation ward (hereafter convalescent rehab ward) is strictly limited, which causes difficulty for patients whose stay exceeds this fixed number of days. As a result there have been concerns for some time that patients expected to recover through rehabilitation may end up being deprived of this opportunity due to prolongation of the number of post-onset hospitalization days. We therefore inquired into and discussed the impact of the length of post-onset hospitalization on prognosis by conducting a survey. The subjects were patients administered to our unit in the hospital for rehabilitation prior to establishment of the convalescent rehab ward, and questions surrounded the reasons for extension in length of stay after onset, and length of stay in convalescent rehab ward and outcomes (rate of discharge to home). (Results) The length of stay and outcomes (rate of discharge to home) were 91.7 ± 65.8 days and 80.1% for the group of patients (group I : 73 cases) who were within the limited period of length of stay after onset, while the group of patients who exceeded the limited length of stay (group II : 34 cases) yielded more favorable results with 109.7 ± 58.8 days and 67.6%. Although no significant difference in results was observed. Furthermore, the majority of group II (known causes of 25 out of 34 cases) extended the length of their post-onset hospitalization for reoperative surgery, comorbidity and treatment of complications, and satisfactory rehabilitation outcomes were observed, in 23 out of 34 cases (67.7%) being discharged home. From these results we believe that difficulty in admitting patients into the convalescent rehab ward merely because they have exceeded the maximum length of hospital stay is a big problem, and there is a need to improve the medical system after hospitalization.
    View full abstract
    Download PDF (359K)
  • CHANGES IN BLOOD FLUIDITY IN THE EARLY STAGE OF HEPATOPATHY
    Tsutomu ANZAI, Shintaro ISHIKAWA, Takako ISHIKAWA, Yoichi IKENOYA, Tak ...
    2011 Volume 71 Issue 6 Pages 602-609
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.602
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    The present study was designed to examine the influence of the early stage of hepatopathy on blood fluidity. F344 male rats were fed chow containing 3'-methyl-4-dimethylaminoazobenzene at 0.06% (DAB) or regular diet (control). These rats were sacrificed 16 weeks after for the experiments. Histological observation of liver obtained from DAB intake rats showed fatty degeneration and atypical cells, indicating that oral administration of DAB for 16 weeks caused the early stages of hepatopathy in rats. We then examined blood fluidity and the levels of platelet aggregation by using a Micro Channel array Flow Analyzer and a PA-20, respectively. The fluidity of the blood obtained from DAB intake rats decreased and platelet aggregation increased as compared with those of control. In the DAB intake group, platelet aggregation might have been enhanced by inflammatory substances and cytokines in addition to changes of hepatic metabolic function resulting in a decrease of blood fluidity. Our results suggest that blood fluidity and platelet aggregation examination may be useful as an index of early stage in hepatopathy.
    View full abstract
    Download PDF (1140K)
  • SURVEY OF PEAK INSPIRATORY FLOW AND ITS PREDICTOR AMONG PATIENTS WITH ASTHMA
    Ayako OHWAKI, Akihiko TANAKA, Takuya YOKOE, Satoshi MATSUKURA, Yoshita ...
    2011 Volume 71 Issue 6 Pages 610-615
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.610
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Background: The decline of peak inspiratory flow (PIF) reduces the effectiveness of inhaled corticosteroid (ICS). The purposes of this study were to survey the PIF and its predictive factor among patients with asthma using ICS. Methods: One hundred thirty patients (males 47, females 83) with asthma were recruited. PIF was measured with In-Check Dial for which the discus type adaptor was used. Results: The average level of PIF was 86.9±26.9 L/min, and PIF of males was significantly higher than that of females. Even after adjustment of PIF for age and height, PIF of males was still significantly higher than that of females. Six (4.6%) patients (5 females) showed PIF of lower than 50 L/min. Age, height, %FVC, %FEV1, and ACT (Asthma Control Test) showed significant correlations, however, BMI and FEV1% had no correlation with PIF. Multivariate analyses adjusted for each parameter showed a significant correlation with PIF; significant correlations between PIF and age, %FVC, and %FEV1, were revealed suggesting that these parameters were independent factors which can be considered to predict the levels of PIF. Conclusion: Our results show that when providing ICS for elderly adults, especially women, whose pulmonary function is declined, ICS should be chosen considering that their PIF might be declined.
    View full abstract
    Download PDF (401K)
  • BLOOD VESSEL OCCLUSION USING HIGH-INTENSITY FOCUSED ULTRASOUND (HIFU): MINIMALLY INVASIVE TREATMENT OF FETAL TUMORS
    Sayo HOTTA, Akira TOKI, Tetsuko ISHII, Hiromasa YAMASHITA, Takashi KAK ...
    2011 Volume 71 Issue 6 Pages 616-624
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.616
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    In general, fetuses with sacrococcygeal teratoma (SCT) are at risk of high output cardiac failure with hydrops. The aim of this study was to evaluate feasibility of high-intensity focused ultrasound (HIFU) for minimally invasive treatment of fetal SCT. HIFU is an acoustic technique that utilizes the ultrasound power to exclusively thermocoagulate target tissues without damaging its overlying and underlying organs or tissues.
    In our study, all animal experiments were conducted under general anesthesia using a specifically designed transducer (4.44 MHz, 38 mm in diameter, focal distance of 42 mm). With the use of five Japanese white rabbits, three intrarenal arterial branches were targeted and coagulated (day 0). Each HIFU procedure was performed underwater (in saline) after freely mobilizing the left kidney (with its vascular pedicle) from surgically exposed retroperitoneal space. Likewise, on postoperative day 7 and 14, the intrarenal arterial branches underwent HIFU irradiation. Before and after each HIFU procedure, flow velocity of the hilar renal artery was measured using color flow Doppler. These experimental animals were sacrificed on postoperative day 28. Immediately after sacrifice, each harvested kidney was grossly inspected and weighed with the following histological examination of the irradiated (left) as well as non-irradiated (right) kidneys. In all five experimental animals, renal arterial flow velocity soon decreased after HIFU procedures and in four, the irradiated kidney weighed significantly less as compared with each contralateral kidney. In summary, HIFU irradiation successfully reduced blood flow of the targeted renal arteries. Thus, HIFU is expected to be useful for occluding feeding blood vessels of the tissues. In conclusion, HIFU irradiation is likely to become an effective and minimally invasive means of treating intraamniotic fetal tumors.
    View full abstract
    Download PDF (879K)
  • COMPARISON OF BMI-FOR-AGE PERCENTILE WITH WEIGHT-FOR-HEIGHT IN SCHOOL-AGE CHILDREN: ANALYSIS OF THE JAPANESE SCHOOL HEALTH EXAMINATION SURVEY 2000
    Keiko NAGAHARA, Kazushige DOBASHI, Kenichiro TAKAHASHI, Kazuo ITABASHI
    2011 Volume 71 Issue 6 Pages 625-631
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.625
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Body mass index (BMI)-for-age percentile is the international method used for the evaluation of overweight and underweight in children. While weight-for-height (WFH) score, which is the percentage of standard weight by the height for each sex and age, is commonly used in Japan, with obese children being defined as those whose WFH is more than 120%. In our study, we compared both definitions by the anthropometric data of 270,720 elementary (6 to 11 years) and 225,600 junior high school students (12 to 14 years) based on the Japanese school health examination survey 2000. First, the WFH scores were calculated for tall (mean +2 SD), average and short (mean −2 SD) boys and girls whose weight was obtained from 95th or 5th percentile BMI for the age in every school grade. In both cases, the WFH scores were higher in short than in tall students, meaning that tall students are easily defined as overweight, while short students tend to be evaluated as underweight by using BMI-for-age. Then the BMI-for-age percentiles were calculated for tall, average and short students whose WFHs were 120% and 80%. The BMI-percentile values widely fluctuated in both boys and girls, even though WHF scores were constant. Based on the results of this study, it is that WFH method is more appropriate for evaluation of adiposity among school-age children.
    View full abstract
    Download PDF (307K)
  • THE INHIBITORY EFFECT OF LIDOCAINE ON LPS-INDUCED NEUTROPHILIC AIRWAY INFLAMMATION IN A MOUSE MODEL
    Masahide MIYAMOTO, Akihiko TANAKA, Takuya YOKOE, Toshiyuki TAZAKI, Yos ...
    2011 Volume 71 Issue 6 Pages 632-637
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.632
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Lidocaine, widely used as a local analgesic or an anti-ventricular arrhythmia agent, is known to have an anti-inflammatory effect. We investigated the effect of lidocaine on pulmonary inflammation induced by the exposure of lipopolysaccharide (LPS) in mice. LPS-induced lung injury model was established by the intratracheal exposure of LPS to male C57BL/6 mice at 8-10 weeks of age. Lidocaine at 3 or 30 mg/kg was injected intraperitoneally 30 minutes before exposure of LPS. Bronchoalveolar lavage fluid (BALF) and peripheral blood were collected 24 hours after the administration of LPS. Total cells and differetial cell counts in BALF were measured. Interleukin-6 (IL-6) in BALF was measured using enzyme-linked immunosorbent assay. Injection of lidocaine alone by the intraperitoneal route did not alter any cell population in BALF and peripheral blood compared to vehicle control. Treatment with lidocaine significantly reduced the alveolar recruitment of neutrophils in BALF. In concordance with the downregulation of neutrophils, lidacaine reduced the concentration of IL-6, highly associated with neutrophilic inflammation, in BALF. These results suggest that systemic treatment of lidocaine can suppress LPS-induced neutrophic inflammtion in a murine model.
    View full abstract
    Download PDF (442K)
Case Report
  • A CASE OF ANAPHYLAXIS ASSOCIATED WITH LATEX ALLERGY THAT OCCURRED TWICE IN THE LATEST OPERATIONS DESPITE LACK OF ALLERGY SYMPTOMS IN PREVIOUS OPERATIONS
    Satomi AZUMA, Kiyoko BITO, Kazumasa YASUMOTO
    2011 Volume 71 Issue 6 Pages 638-643
    Published: December 28, 2011
    Released on J-STAGE: August 03, 2012
    DOIhttps://doi.org/10.14930/jsma.71.638
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    We report an 11-year-old girl who despite having had no allergies, developed severe anaphylactic shock under general anesthesia on two occasions, and was diagnosed with latex allergy. The patient had undergone general anesthesia a total of five times by the age of 10 without any notable abnormalities. Retrograde urography was performed under general anesthesia for vesicoureteral reflux, but airway pressure increased 25 min after the injection of urography, and SpO2 became unmeasurable. Anaphylaxis was suspected, and the symptoms improved following adrenaline administration. Because the contrast agent was strongly suspected to be the cause of anaphylaxis, no further examination for identifying the allergen was performed. Fifteen months later, the patient again exhibited anaphylaxis when disimpaction was performed under general anesthesia for constipation, and the symptoms improved following adrenaline administration. Postoperative tests revealed that the patient's serum latex-specific IgE titer was positive strongly (class 6), and the patient was diagnosed with latex allergy. It is necessary in cases of intraoperative anaphylactic shock to consider latex allergy as a possible cause and to perform close examination. In addition, a latex-free environment should be established to prevent recurrence.
    View full abstract
    Download PDF (512K)
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top