Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 31, Issue 11
Displaying 1-5 of 5 articles from this issue
  • Mitsuru Momma
    1971 Volume 31 Issue 11 Pages 567-587
    Published: November 28, 1971
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The antagonistic effects of anabolic steroid (oxymethenolone) to adrenocortical hormone (hydrocortisone acetate) in the proximal cartilaginous end of tibia of the eighteenth day chick embryo were studied by administering both hormones simultaneously to the seventh day chick embryo of incubation.
    The results are summarized as follows:
    1) Dwarfism due to adrenocortical hormone is improved by administering an adequate amount of anabolic steroid. Death rate, lenth of tibia, and body weight is also improved.
    2) The growth of the epiphyseal cartilage of long bones is parallel to the length of long bones.
    3) An enlargement of a medullary cavity, an improvement in the clearness of boudaries between cartilaginous zones, an increase in the regularity of the arrangements of columnar cartilaginous cells and an appearance of osteoblasts are recognized histologically.
    4) In sections stained with PAS, a marked increase in glycogen is found in the matrix of resting cartilaginous zone of the combined administrations group.
    5) In sections stained with alcian ble and toluidine blue, increase in acid mucopolysaccharide is found in the matrix of the columnar cartilaginous zone and the calcifing cartilaginous zone of the combined administration group compared with the adrenocortical hormone group.
    6) By means of alkaline phosphatase staining, the combined administration group has the same amount increase in alkaline phosphatase as the control group.
    7) The above facts show that an adequate amount of anabolic steroid reacts antagonistically to adrenocortical hormone and it also improve environments for ossification.
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  • Akira Fukuda
    1971 Volume 31 Issue 11 Pages 588-604
    Published: November 28, 1971
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Many factors that give rise to postastrectomy syndromes, especially dumping syndrome, have been reported.
    For the purpose of evaluating how relationship between glucose metabolism and serum insulin in postgastrectomy, the author studied the postprandial determination of serum insulin and blood sugar after gastrectomy. Postprandial determination of serum insulin was determined by the modified methode of Hales and Randle, using 125I-INSULIN.
    On the result, value of blood sugar and serum insulin on patient with dumping syndrome, high level was demonstrated than the other patients. Value of hypoglycemia have been evoked of high insulinemia at the same time of late dumping symptoms.
    Above the result, the late dumping syndrome may be caused as change of blood insulin levels.
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  • Terumitsu Watabe
    1971 Volume 31 Issue 11 Pages 605-616
    Published: November 28, 1971
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Haemodialysis was perfomed acute renal failure untill 1960, but recently haemodialysis has evolved for chronic renal failure and established longterm intermittend haemodialysis.
    Studies mere perfomed to examine of haemodialysis for 36 chronic renal failure patients, from 1960 to 1970, and parted them, either first period (from 1960 to 1968), later (from 1965 to 1970), compared them cbout dialysis efect and the others.
    Two cases out of 16 patients, the later (from 1968 to 1970), perfomed renal transplantation.
    Studies into the causes of these cases and longterm intermittend haemodialysis for chronic renal failure.
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  • I. Maternal thrombocytes during pregnancy, at parturition and in the puerperium and platelets of the neonate
    Hitoshi Kubota
    1971 Volume 31 Issue 11 Pages 617-626
    Published: November 28, 1971
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Problems pertaining to obstetrical hemorrhage are of extreme clinical importance. As an integral part of the study of various properties of the blood related to obstetrical bleeding, a clinical study representing an attempt to clarify variations in platelet counts of mothers during pregnancy, at parturition, in the puerperium, with late toxemia of pregnancy, at threatened abortion and at caesarian section, of the umbilical cord blood, and of the newborn was pursued. Clot retraction rates were also studied.
    1) The thrombocyte count for all blood samples obtained from nonpregnant women in normal health was 33.3±3.32±104 per cu. mm. (mean±standard error of the mean), and the clot retraction rate 50±5.1 per cent, respectively.
    2) In the group of women with normal pregnancy the platelet count was 26.59±7.57×104to 29.02±9.12×104per cu. mm. on the average, the value diminshing progressively with the course of gestation, reaching the lowest level at 8 to 9 months of pregnancy, and in-creasing rapidly thereafter to rise to an average level of 37.93±11.12×104per cu. mm. on the sixth day of puerperium. The platelet count in these subjects became restored to the level in the nonpregnant by the thirtieth day post parturition. The pregnant women displayed clot retraction rates generally higher than those shown by the non-pregnant ; the rate for all blood samples obtained from the former was 49±9.4 per cent to 54±6.2 per cent, the trend toward increase emerged in the intermediate stage of gestation, and the rate began decreasing on the sixth puerperal day to fall to a level of 50±8.0 per cent on an average.
    3) The group of neonates born by full-term delivery showed an umbilical cord arterial platelet count of 31.71±7.91×104per cu. mm. and an umbilical cord venous platelet count of 32.55±8.28×104per cu. mm., respectively. There was no evidence of difference in these counts between the sexes whereas a slightly positive correlationship was noted to exist between the mother and the newborn. The neonatal platelet count was observed to be frequently diminished on the sixth day after birth, as compared with that noted immediately upon delivery. The umbilical cord venous blood showed a clot retraction rate of 39±8.7 per cent, and the umbilical cord arterial blood a rate of 38±4.0 per cent, respectively, on the average.
    4) For all blood samples drawn from mothers undergoing caesarean operation, the thrombocyte count was observed to be lowered immediately after the section, to show a tendency to recovery from the first postoperative day on, and eventually to rise above the preoperative level in the first or second week operation, followed by a gradual diminution to return to the normal level.
    5) Both the maternal platelet count and clot retraction rates of the group of women seriously ill with late toxemia of pregnancy and of that of mothers slightly ill with the same disease did not differ significantly from those of women with normal gestation.
    6) Neither the group of threatened abortions with favorable prognoses nor that with poor prognoses displayed significant aberrations from the group of normal pregnant subjects with respect to platelet count and clot retraction rate. In the group of threatened abortions with favorable prognoses, however, diminution of maternal platelet count was in evidence following administration of progesterone.
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  • Tasuku Wada, Hikozo Shinagawa, Kunihiko Sato, Mikio Kanda
    1971 Volume 31 Issue 11 Pages 627-633
    Published: November 28, 1971
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    A case of chordoma, asising from sacrum of a 63 year old man complaining lumbago was reported.
    A few relevant literature were reviewed.
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