Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 25, Issue 8
Displaying 1-5 of 5 articles from this issue
  • [in Japanese]
    1965 Volume 25 Issue 8 Pages 285-305
    Published: November 28, 1965
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • Report 2. Changes of Serum Copper and Serum Ceruloplasmin with Variation in Hemoglobin and the Number of Erythrocyte and Leucocyte at Various Stages of Labor, Puerperium
    Tadashi Hayashi
    1965 Volume 25 Issue 8 Pages 306-325
    Published: November 28, 1965
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The amounts of serum copper, serum ceruloplasmin, hemoglobin values and the number of erythrocyte and leucocyte, were measured in women at the varous stages of normal labor, and the normal puerperal stage, and with toxemia of late pregnancy. In addition to that, the fetal navel strings of normal delivery and the normal pregnant women at the end of the 10 th month of pregnancy were also investigated as controls. Thus, the total number of cases investigated in this experiment was 255.
    In the women of normal labor and puerperium, the serum copper begun to increase from the onset of labor than that of the terminal stage of pregnancy and showed the maximal values at the 2 nd stage of labor. Serum ceruloplasmin indecated no significant changes through the various stages of labor.
    Both values of serum copper and serum cerulopasmin started to decrease immediately after the delivery and returned to the value of normal non-pregnant women within the 1 St month of puerperium.
    In regard to the blood findings, with the onset of labor, erythrocyte counts gradually increased, but the content of hemoglobin indicated no significant change. However, after the delivery, bath values gradually decrease up to the 4 th day of puerperium, then recovered to the normal value showing gradual increase within the 1 st month of parturition. Leucocyte counts prominently increased with the onset of delivery reaching the maximum at the 3 rd stage of parturition.
    Immediately after the delivery the number of leucocytes rapidly decreased, then showed a gradual decrease and returned within normal values.
    In the late toxemia of pregnancy, the serum copper and serum ceruloplasmin indecated the similar changes to those in normal pregnancy and puerperium, with higer values than these two condtions. However, hemoglobin values and erthrocyte counts showed the lower values than these in normal condition. In contraly, leucocytes markedly increased showing a high value even after the 1st month of puerperium.
    As to the blood of navel string, the serum copper level was found somewhat lower than that in the healthy nonpregnant women, and serum ceruloplasmin level was extremely low. Further, the hemoglobin values, erythrocyte counts and leucccyte counts increased in comparison to those of adults.
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  • Iwao Noguchi, Arinaga Mori, Koichi Shimizu, Noboru Matsunaga
    1965 Volume 25 Issue 8 Pages 326-330
    Published: November 28, 1965
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Relation between the configuration of the action potential and membrane potential was studied. Measuring the membrane potential by intracellular electrod, the environmental conditions was changed. The mean of the normal membrane potential was -55 mV, and the maximum -65 mV, minimum -45 mV.
    Nernst's theoretical formula was favered for the relation between the logarithm of KCI concentration and membrane potential in the range of relative high concentration of it. KCl increased environment, caused to lower the membrane potential and decreased the slow component of the action potential. Substitution of NaCI in Krebs solution by isotonic sucrose or choline caused to diminish the slow potential, but had little effects on the membrane potential. In CaC12 decreased Krebs solution, the repitative spike potentials vanished, but the value of membrane potential was not so much altered. The membrane was depolarized by acetylcholine and the action potential was intensified.
    We could recognized no decisive relation between change of the membrane potential and the configuration of the action potential.
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  • Keizo Takahashi, Masakazu Kawasumi, Yoshio Igarashi, Michi Matsumoto, ...
    1965 Volume 25 Issue 8 Pages 331-334
    Published: November 28, 1965
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The observations were made on postoperative side effects, especially hemorrhagic tendecy and postoperative jaundice in three cases who had received about ten thousand ml. of whole blood for gynecological operation.
    Hemorrhagic tendecy, uremia, pulmonary edema and serumhepatitis were observed in 2 patients, while no side-effect was found in other one case.
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  • Michi Matusumoto, Akiyoshi Hosoyamada, Chin Ming Chang, Masakazu Kawas ...
    1965 Volume 25 Issue 8 Pages 335-339
    Published: November 28, 1965
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Hypotension, one of the complications in general anesthesia with nitrous oxide, Oxygen and Methoxyflurane supplemented with spinal analgesia, was protected by injecting Effortil intramuscularly prior to spinal analgesia. Effect of effortil on arterial blood pressure appeared in 5 to 10 minutes after intramuscular administration, reached to the maximum in 15 minutes and lasted for 45 minutes. However, it was less effective in elderly patients over 60 years of age and in patients with hypertension, cardiac disorder, anemia, hepatic dysfunction or hypoproteinemia. No side effect of Ef f ortil was noted. Inhalated Methoxyflurane seemed to have a cause for hypotention in general anesthesia supplemented with spinal analgesia.
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