Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 62, Issue 6
Displaying 1-10 of 10 articles from this issue
  • [in Japanese]
    2002 Volume 62 Issue 6 Pages 357
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese]
    2002 Volume 62 Issue 6 Pages 358-363
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Download PDF (606K)
  • [in Japanese]
    2002 Volume 62 Issue 6 Pages 364-367
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Download PDF (393K)
  • [in Japanese]
    2002 Volume 62 Issue 6 Pages 368-373
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese]
    2002 Volume 62 Issue 6 Pages 374-378
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • Genshu TATE
    2002 Volume 62 Issue 6 Pages 379-387
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The hedgehog (HH) gene, one of the segment polarity genes of Drosophila, was initially reported in 1980. The HH gene encodes a secretory protein and the Patched (PTCH) gene encodes an HH receptor. Recent reports have indicated that HH signaling molecules are involved in not only morphogenesis but also carcinogenesis. In this review, human diseases involved in mutations of HH and PTCH genes, as well as genes that encode the downstream transcriptional factors for the HH-PTCH signaling system, will be described.
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  • —Indication for laparoscopy assisted distal gastrectomy with D1+βlymph node dissection and operative method—
    Satoshi SUZUKI, Takashi KATOU, Tsutomu KAETSU, Kouji MOROHARA, Kimiyas ...
    2002 Volume 62 Issue 6 Pages 388-395
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We report a study of laparoscopy-assisted distal gastrectomy with D1+βlymph node dissection (LADG with D1+β) for submucosal gastric cancer located in the middle and lower third of the stomach. Indications for LADG with D1+β were studied from lymph node metastases of cases of open distal gastrectomy. A significant difference was found in the lymph node metastasis rate according to the enlargement of tumor diameter. Only one Pathological N2 case was recognized in submucosal gastric cancer less than 40 mm with a differentiated type and less than 20 mm with an undifferentiated type. However, this case has not been recurrent. therefore, the indications for LADG with D1+βare 1. submucosal gastric cancer with a differentiated type of more than 15 mm and less than 40 mm, and 2, submucosal gastric cancer with an undifferentiated type of less than 20 mm. In the operating method, five trockers are inserted, and a laparoscope is put below the navel. All lymph node dissections are finished laparoscopically. A longitudinal dissection with 5 cm is put under the xiphisternum and distal gastrectomy is performed. Reconstruction is done by the Billroth I method. In laparoscopy-assisted distal gastrectomy, the mean dissected lymph node number is the same, the mean operating time is longer and the mean blood loss is less than in open distal gastrectomy.
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  • Akihiro MATSUHASHI, Takao SATO, Shintaro ISHIKAWA, Tadashi HISAMITSU
    2002 Volume 62 Issue 6 Pages 396-400
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Stiffness of the leg muscle after physical exercise was measured objectively and quantitatively with a newly devised muscle hardness meter. It is well known that strenuous exercise may cause some stiffness of muscles by questionnaire or palpation. However, there are only a few reports concerned with objective measurement of muscle stiffness. We measured the time course of leg muscle stiffness after unilateral toe standing. In the case of unilateral toe standing on a flat floor, muscle hardness of the loaded side was elevated after physical exercise and diminished gradually. However muscle stiffness of the opposite non-loaded side also elevated. These results indicate that in the case of unilateral toe standing on a flat floor, the soleus muscle on the other side must be suspended and not touch the floor surface. This suspension may add a load to the soleus muscle on the other side. Avoiding these effects in the following unilateral toe standing was performed on a platform for completely relaxing the other leg muscle. In this condition the soleus stiffness elevated at only the loaded site. These results suggest that the device developed in our laboratory was very sensitive to muscle loading.
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  • Akihiro MATSUHASHI, Takao SATO, Shigeru ASAHINA, Tadashi HISAMITSU
    2002 Volume 62 Issue 6 Pages 401-406
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We measured the hardness of the soleus muscle of male students objectively using a newly designed device. After tiptoe standing, hardness of the muscle elevated and gradually decreased according to a time course. The percent of decreases between soon after and 1 min after tiptoe standing were -10.4% in the non-stretching side and -24.1% in the stretching side. A statistical significance was observed between these values. Passive stretching of the muscle accelerated the time course of recovery from hardening after physical exercise. However, passive stretching did not diminish the hardness of the rest muscle. It is well known that stretching recovers muscle elasticity subjectively or by palpation. In this study we objectively demon-strated that stretching is able to soften the muscle after physical exercise.
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  • Ikuyo TOBITA, Yuto KUWASAKO, Kiyoko INOUE, Takasi TOI, Kazumasa YASUMO ...
    2002 Volume 62 Issue 6 Pages 407-410
    Published: December 28, 2002
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We describe the use of the laryngeal mask airway for management of acute upper airway obstraction. A 20-year-old female patient underwent mandiblar osteotomy under general anesthesia. The subject suffered acute upper airway obstruction due to submucosal bleeding of the oral cavity 40 minutes after general anesthesia. Intubation of a tracheal tube using a laryngoscope was not successful. Moreover, face mask ventilation was tried but was not successful. She was immediately rescued using the laryngeal mask airway. The laryngeal mask airway is an effective in resuscitating patients who have developed severe upper airway obstruction.
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