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Volume 14, Issue 1
Displaying 1-11 of 11 articles from this issue
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Iwao Oya1954 Volume 14 Issue 1 Pages 1-7
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (922K) -
Toshimasa Sakamoto, Yoshiaki Inoue1954 Volume 14 Issue 1 Pages 8-11
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDuring the daily routine, internists often have experience of cases who complain of various symptoms and appearently look like cases of neurosis, but are actually proved to be cases of low blood-pressure when the blood pressure was determined.
In the present paper, the authors describe various clinical observations on the essential low blood-pressure omitting the symptomatic low blood-pressure and discuss the nature thereof.
1) As to the symptoms, fatigue, headache, dizziness, stiff shoulders and cold sensation in the extremities are characteristics of this disease. In addition, the authors reproduced experiments hitherto reported and commented on the cause of this disease.
2) As to the discussion on the nature of this disease, the authors recognized, in most cases, functional deteriolation in the system of hypophysis and the cortex of the suprarenal gland by Thorn's tests.
3) In the hematological findings, due to increase in the number of eosinophile and lymphocyte, a characteristic curve was recognized in ELMoNogram.
In view of the above, the authors consider that the functional deteriolation in the system of hypophysis and the cortex of the suprarenal gland is playing an important role in the cause of this disease.View full abstractDownload PDF (415K) -
Shiro Ogawara1954 Volume 14 Issue 1 Pages 12-14
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe second formula of the forearm was worked out from one length and three circumferences of the forearm. The quantitative measurements were as follows :
1) Length of forearm : straight distance from the stylion radiale to the radiale using the direct method of measurement.
2) Circumference I of forearm : largest circumference, hanging upper extremity, of the forearm,
3) Circumference II of forearm : generally termed the middle circumference, of the forearm,
4) Circumference III of forearm : generally termed the smallest circumference of the forearm.
From these quantitative measurements, the following six indices were drawn; namely,
i) Forearm length-circumference index I (= length of forearm ⋅ 100/circumference I of forearm),
ii) Forearm length-circumference index II (= length of forearm ⋅ 100/circumference II of forearm),
iii) Forearm length-circumference index III (= length of forearm ⋅ 100/circumference III of forearm),
iv) Forearm circumference index A (= circumference II of forearm ⋅ 100/circumference I of forearm),
v) Forearm circumference index B (= circumference III of forearm ⋅ 100/circumference I of forearm),
vi) Forearm circumference index C (= circumference III of forearm ⋅ 100/circumference II of forearm) .
These indices were sought from the anthropological ages of many cases of men and women and centered around arithmetical averages of indices ; six types of classifications were made with considerations for standard variations.
These types were symbolized simply one to six which in turn were charted in parallel arrangements in the order of indices LUI LUII LUIII UA UB UC, producing a form which was named the Second Formula of the Forearm.View full abstractDownload PDF (295K) -
Hirosi Toriumi, Ichiro Imamura1954 Volume 14 Issue 1 Pages 15-17
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA single nerve fiber was prepared by the technique of Tasaki from the sciatic nerve of the toad. The proximal trunk of the nerve was stimulated by two successive induction shocks. The action currents were led from the Ranvier's nodes of a single fiber, and recorded by Braun tube oscilloscope. When the interval of the two stimuli was shorter than 2.2 msec., the second stimulus failed to evoke the action current. If the interval was prolonged more than 2.2 msec., there appeared the second small action current. Its conduction velocity was slow. With the prolongation of the interval, the conduction velocity and the strength of the action current were increased. When the interval was increased more than 9.5 msec., the action current evoked by the second stimulus exhibited normal strength and normal conduction velocity. cupermormal velocity of conduction has never been observed in our experiments.View full abstractDownload PDF (2919K) -
Kenichi Irisawa, Akira Sakai, Shigetsugu Yamaguchi1954 Volume 14 Issue 1 Pages 18-22
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSEmpolying the absorption test of lithion carmin by the Kupffer's stellate endothelial cells of mouse liver, the influences of various antituberculosis drugs on the reticuloendothelial system were investigated. When one dose calculated from the usual human dose of an antituberculosis drug (1g/50kg of SM, 2g/50kg of PAS-Na, 0.2g/50kg of INAH or 0.02g/ 50kg of TB1) was administered to mice, it was found that the influence exercised by PAS-Na on the reticuloendothelial system is milder compared with those by the other drugs. The other drugs were found to have activated the system approximately in a same degree. The phagocytic activity of the system was found to demonstrate a tendency of lowering the activity when administered for 5 consecutive days on the contrary. When the above doses were increased by 5 times respectively and given in one injection, the system was generally activated, although the influence by INAH was found milder than others. When the same dose was administered for 5 consecutive days, the activity in many cases were found lowered although TB1 activated in a fair degree. Further, when SM combined with other 3 drugs was given in one dose, or when a large dose exceeding its lethal dose was given in one dose, activation was recognized.View full abstractDownload PDF (630K) -
Influences of Atropine and Scopolamine on the Chick Embryo and their Fates in the EmbryoTamiharu Kawauchi1954 Volume 14 Issue 1 Pages 23-41
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSAs part of the studies on the embryonal stage, the author investigated the influences of atropine and scopolamine on the chick embryo and their fate in the embryo. Further, the author attempted to estimate the degree of the disturbance of the organ by investigating the influences of both alkaloids on the splitting action of the chick embryo liver on protein and diglycine.
Even when 5mg of atropine and scopolamine were injected, the eggs were successfully hatched. When the toxicity of atropine and scopolamine were compared in the cases where the eggs died, the results indicated that the toxicity of atropine is stronger than the other. The excretion of these two substances is extremely minute. The tendency of accumulation of these substances in the liver was observed, but it was also found to be very slight. Most part of these substances injected was considered to be splitted in the eggs or in the embryonal body. No remarkable difference in the splitting capacity of the liver of the chick embryo treated with these substances compared with that of untreated control.View full abstractDownload PDF (2785K) -
Susumu Honda1954 Volume 14 Issue 1 Pages 42-62
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSBelieving that the knowledge in the absorption of histamine in the intestinal tract and in the influence of various chemicals on the absorption of histamine not only play an important role in the investigation of the cause of Ekiri-like disease, ileus etc. but also is very significant to the treatment of these diseases, the author conducted experiments concerning the absorption of histamine in the small intestine, and further investigated the influence of various substances administered in combination with histamine on the accumulation of histamine in the liver after the absorption.
Nakamura's method was employed for the extraction of histamine, and a biological method was used for the quantitative estimation of histamine. For quantitative estimation of blood sugar, Hagedorn-Jensen's method was employed, and for quantitative estimation of sulfonamide, Tsuchiya-Kawamura's modification employing p-dimethyl-aminobenzaldehyde was used. Samples of blood were taken by heart puncture 30 minutes after the drug was introduced. In the cases of animals died within 30 minutes from the introduction of the drug, samples were taken immediately after the death. The liver was taken out immediately after the bleeding by heart puncture. In the case when the animals did not die within 30 minutes from the introduction of the drug, the liver was taken out immediately after the bleeding to death. As to the method of administration of drugs, intraduodenal introduction was generally employed.
The principal results obtained are as follows :
Histamine hydrochloride is absorbed well from the small intestine even by single introduction. However, the absorption is greatly affected by the room temperature. The absorption of histamine is enhanced at a higher room temperature. In the case when the histamine solution is on the acid side, the absorption of histamine in the small intestine is slightly enhanced contrary to the case when the histamine solution is on the alkaline side. Cattle bile or calcium chloride, especially cattle bile, remarkably enhances the absorption of histamine. Glucose or fructose evidently inhibits the accumulation of histamine in the liver.View full abstractDownload PDF (11259K) -
Toshio Morita1954 Volume 14 Issue 1 Pages 63-83
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe present knowledge concerning the absorption of histamine in the large intestine cannot be regarded as complete as yet. In parallel with Honda's experiments concerning the absorption of histamine in the small intestine, the author investigated the absorption of histamine in the large intestine and the influence of various substances thereon. In the present paper, aminoacids, sugars, calcium chloride, cattle bile and “ Sprase ” were firstly dealt with as the substances administered in combination with histamine. Further, the influence of pH on the absorption of histamine in thej large intestine was also studied. As the result, the following conclusions were drawn.
Though almost no absorption of histamine hydrochloride in the large intestine is recognized at the room temperature of 14.0°-28.0°C when administered alone, the influence of higher room temperatures thereon cannot be ignored. The absorption in the large intestine is observed when the room temperature rises to 31.0°-32.5°C. When the histamine solution is on the acid side, a slight enhancement of the absorption of histamine in the large intestine is recognized contrary to the case when the histamine solution is on the alkaline side. As it is in the case of the absorption of histamine in the small intestine, the absorption of histamine in the large intestine is most remarkably enhanced when histamine is administered in combination with cattle bile.View full abstractDownload PDF (32146K) -
(Report II & III) With Reference to the Results of the Return Inoculation into MiceS. Umeda1954 Volume 14 Issue 1 Pages 84-98
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn our Department of Pathology, Y. Kato reported that the blockade by gluey matters to the reticuloendothelial system of the adult rabbit furnishes a favourable condition to the infection of the Japanese encephalitis virus (Nakayama strain) and makes the invasion and propagation of virus easier by reducing the resistance of the rabbit to the virus.
Recently, the author succeeded in the return inoculations into mice successively, and reached the following conclusions. The results are reported from the clinical and pathological-histological point of view.
1. The amity of the Japanese encephalitis virus (Nakayama strain) inoculated into the rabbit to the brain-tissue becomes lower for a short period of time, but this affinity is recovered by successive mouse panages.
2. The svccesseive mouse pascages do not exercise big influence on the obstruction of circulation of the blood and the diffuse proliferation of glia cells.
3. The injuries to the tissue, the degeneration of ganglion cells and the formation of small nodules of gliacells tend to increase by the serccesive mouse passages.
4. The following is the author's opinion on the mice highly susceptible to the Japanese encephalitis virus : When a mouse becomes infected with the virus, loasening of the tissue, demyelinization, vecrosis and formation of small nodules of gliacells are seen as corrective and reactive functions against the injurious function of the virus to the tissue. The abone reactine funation possesses a defending effect against the virus in the diffusely proliferating gliacells.
5. In the present experiments, humidity (43%-94% in-door) did not exercise any obvious influence on the mice of appearance of these changes, but temperature (6°C⋅30°C in-door) affested the results to a considerable degree. Specifically, when the room temperature exceeded 10°C, the mice was found higher, therefore, the stability of these results were recognized.View full abstractDownload PDF (6674K) -
Shu Oka1954 Volume 14 Issue 1 Pages 99-100
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (216K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1954 Volume 14 Issue 1 Pages 101-103
Published: March 31, 1954
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (449K)
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