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Volume 63 (2003)
- Issue 6 Pages 527-
- Issue 5 Pages 453-
- Issue 4 Pages 335-
- Issue 3 Pages 235-
- Issue 2 Pages 111-
- Issue 1 Pages 1-
Volume 63, Issue 2
Displaying 1-15 of 15 articles from this issue
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[in Japanese]2003 Volume 63 Issue 2 Pages 111-112
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese], [in Japanese]2003 Volume 63 Issue 2 Pages 113-116
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese], [in Japanese]2003 Volume 63 Issue 2 Pages 117-123
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese], [in Japanese]2003 Volume 63 Issue 2 Pages 124-127
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese], [in Japanese]2003 Volume 63 Issue 2 Pages 128-129
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
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Asami HONGO, Yoshiharu HOSHIYAMA, Takeshi KAWAGUCHI2003 Volume 63 Issue 2 Pages 130-141
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe conducted a survey to clarify the relationship between consciousness and strength of SOC (Sense of Coherence) of 86 nursing school students. The questionnaire was related to the ability to cope with and the degree of stress experienced during clinical practice.
The survey, as well as the SOC questionnaire, were carried out twice, once before and after the clinical training class during the first year of students. The results showed that most of the students felt a great deal of stress during clinical practice. Students who had higher SOC scores were better able to handle stress. In addition, students who showed an increase in SOC scores had a more positive attitude toward the clinical practice and were eager to succeed as nurses in the future. At the end of the clinical practice classes, the students with higher SOC scores showed a positive attitude and tended to cope well with stress as indicated by multiple regression analysis. These results suggest that SOC is closely related to the ability of nurses and there is a need for SOC education in the nursing school curriculum.View full abstractDownload PDF (1330K) -
Masaru SANDO2003 Volume 63 Issue 2 Pages 142-153
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSBlock sections were prepared from the five locations-central portion, superior portion, inferior portion, anterior portion, and posterior portion-of the region around the fracture of the femoral head isolated from 21 patients (16 patients with intracapsular fracture, 5 patients with extracapsular fracture) . Cancellous bone microstructure, cortical bone thickness, and bone density were evaluated and analyzed for differences in the mechanism from which intracapsular versus extracapsular fracture and fragility developed. The method of evaluating the bone architecture differed from conventional bone histomorphometry of hard tissues and involved non-invasive micro-CT measurements, while the bone density was measured by pQCT. The results indicate that in comparison to patients with extracapsular fractures, patients with intracapsular fractures showed significant decreases in the trabecular thickness of superior and posterior portions in the cancellous bone. The cortical bone thickness was significantly decreased in the superior portion. Bone density was significantly decreased in the superior portion, while in the extracapsular fracture group density tended to be lower in the inferior, anterior, and posterior portions, although this was not statistically significant. Although there have been previous studies on the bone quality of the femoral head isolated from intracapsular fracture of the femoral head, most reports are of two-dimensional analysis of coronal sections. As far as we are aware, there have been no previous reports comparing individual locations to extracapsular fractures. In view of the various reports that bone density is lower in the extracapsular fracture compared to the intracapsular fracture, we speculate that extracapsular fracture results from the effects of external forces on decreased bone density, while in the intracapsular fracture type, thinning of the superior portion of the cortical bone creates fragile areas in the superior and posterior portions of the cancellous bone; therefore, the factors involved in the development of the fracture are similar to a fatigue fracture.View full abstractDownload PDF (7288K) -
Kenji NARUI, Makoto INOUE, Kayo MIZUTANI, Junya IWASAKI, Daisuke TANAK ...2003 Volume 63 Issue 2 Pages 154-162
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSAlthough it is known that activity of cytochrome P450 1A2 in premature infants is lower than in adults and children, it is difficult to obtain enough blood samples of premature infants to monitor the pharmacokinetics of theophylline. We evaluated theophylline pharmacokinetics in pramature infants with primary apnea by measuring theophylline urinary metabolites and serum conceutrations and assessed the relationships between pharmacokinetics and characteristics of infants including posthatal age and postconceptional age. Changes of theophylline clearance and urine metabolies were investigated in 24 cases of 20 premature infants receiving theophylline therapy at a steady state. The infants gestational ages ranged from 24.7 to 37.0 weeks: postnatal from 3 to 71 days and postconceptional from 29.9 to 38.4 weeks. Total clearance and renal clearance were calculated as 0.251±0.072 ml/kg/min and 0.091±0.047ml/kg/min, respectively Percentage of renal clearance was 36.3%. We concluded that total clearance of theophylline (p<0.005) and renal clearance (p<0.001) correlated with postnatal age and not with postconceptional age in premature infants of less than two months old.View full abstractDownload PDF (675K) -
Katsura SUGIHARA, Kozo UENO, Sachiko YOFU, Tsubura TAKAHASHI, Kaori MI ...2003 Volume 63 Issue 2 Pages 163-173
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe obserued that some patients who have a food allergy also have complicated liver disorders. Because Chinese orient medicine may be increasingly beneficial for allergic diseases, this study at tempted to use Saiko-Seikan-Seikan-To to treat murine liver damage based on a food allergy model. Nc/Jic strain mice with high leveis of serum IgE were first sensitized with OVA and then treated with eit her Saiko-Seikan-To or physiologic saline. We organized 4 groups-Group 1 was unsensitized, Group 2 was sensitized and treated with physiologic saline, Groups 3 and 4 were sensitized and treated with low doses (100 mg/kg/day) and high doses (300 mg/kg/day) Saiko-Seikan-To, respectiviely. Pathological and histological studies revealed serum AST levels, serum ALT levels, and cytokine expression of IL-4, IL-6, TNF-α, CD4. The sensitized mice in Group 2 showed significantly elevated serum AST and serum ALT levels compared to the unsensitized mice. In addition, abnormal hepetic morphology indicated liver damage. Group 2 also suffered villous edema in the samll intestine. With the exception of IL-4, the other cytokines and the frequency of multi-nucleated hepatocytes were significantly higher than in the unsensitized group. Consequently, the data suggest that liver damage was present in this food allergy murine model and conclude that Saiko-Seikan-To may modulate this reaction to prevent liver damage caused by food allergies.View full abstractDownload PDF (6372K) -
Jun IKEDA2003 Volume 63 Issue 2 Pages 174-182
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe etiology of idiopathic carpal tunnel syndrome has not been clarified. A cross sectional area of carpal tunnel, flexor tendons, median nerve, and thickness of transverse carpal ligament were evaluated by MRI. Twenty-six patients who were electrophysiologically diagnosed with idiopathic carpal tunnel syndrome were tested by MRI. All patients were females; the mean age was sixty-four years old. The cross sectional area of carpal tunnel, the median nerve area, the area of the flexor tendons and its synovium in carpal tunnel, and thickness of the transverse carpal liament were calculated. The following are of a seuere type carpal tunnel syndrome: Mean area of the flexor tendons and its synovium in carpal tunnel, 110.5±25.5mm2 (control group; 79.3±13.8 mm2) ; ratio of flexor tendons and its synovium area to carpal tunnel area, 51.6±8.8% (control; 40.5±2.3%) ; and thickness of the transverse carpal ligament, 3.3±0.4mm (control; 2.4±0.4mm) . These mean areas in severe carpal tunnel syndrome were significantly greater than those in mild type (p<0.05 or p<0.01) . From the viewpoint of this result, it is possible that tenosynovitis is strongly to the etiology of idiopathic carpl tunnel syndrome. In other words, synovium edema causes chronic high pressure environment in carpal tunnel. Moreover, we classified these MRI findings into the following subgroups: 1) Enlargement of cross sectional area of flexor tendon and its synovia (n=8; 25.8%), 2) thickened transverse carpal ligament (n=11; 35.5%), and 3) combined type (n=7; 22.6%) .This classification by MRI imaging was related to a clinical course and electro-physiologic severity. The present study suggests that to evaluate the cross sectional, area of an MRI image is useful for diagnosis and cure of idiopathic carpal tunnel syndrome.View full abstractDownload PDF (6719K) -
Akihide SUGIYAMA, Takao OKAMATSU, Masashi YATSUZUKA, Akira GOMI, Jun-i ...2003 Volume 63 Issue 2 Pages 183-192
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe purpose of this study is to investigate the effect of a low residue diet and probiotics in rats with short-bowel syndrome. Male Wistar rats weighing 180g underwent massive resection of the small bowel. Experiment 1: Group A (n=12) were maintained on an enteral diet for four weeks. Group B (n=12) were fed with standard chow for four weeks. After one week and four weeks, the nutritional and fecal conditions were evaluated. After one week, weight gain was lower (p=0.018), and serum total protein level was higher (p=0.034) in Group A. After four weeks, fecal score was higher in Group A (p=0.033) . Experiment 2: Group C (n12) were fed with an enteral diet with probiotics for four weeks. The same indices as Experiment 1 were evaluated and compared with Group A. After four weeks, serum total cholesterol was significantly higher (p=0.034) and omega-3 polyunsaturated fatty acids (EPA, DHA) were significantly higher (p=0.015, p=0.043) in Group C. The fecal score was lower in Group C (p=0.018) . These findings suggest that early enteral nutrition in short-bowel syndrome can be accomplished by a low residue diet with probiotics.View full abstractDownload PDF (1069K) -
Hideki TAKEMURA2003 Volume 63 Issue 2 Pages 193-210
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe thyroid carconoma is different from other head and neck malignant tumors. The thyroid could have various tumors from the viewpoint of pathology as well. Most of these tumors is well differentiated carcinoma, which the growth is very slow and survival rate after surgery is usually good. However, there are some types which will metastasize to lymph node early in the stage such as occult cancer. In addition, there are some types that extend beyond the thyroid capsule, which causes the surgical removal of thesurrounding internal organs such as the trachea. This is a very interesting tumor. We measured p53, Ki-67, C-erb B2, E- cadherin, β-catenin, and examined the correlation with the clinical parameters. We researched the relationship between the biological movement and the thyroid gland cancer by unifying these data to see if these data could be a convalescence factor of thyroid gland cancer. It was proved that in the T classification, which is the size of tumor, and in the simulatneous expression and metastasized lymph node, p53 and/or Ki-67 were detected. Furthermore, in occult cancer, there is p53 as well as an abnormality in the E- cadherin. However, regarding the connection between the data and the state of the cancer, there was no physical evidence to relate the survival rate. The reason for this result is largely due to the fact that thyroid gland cancer is operative except for the distant metastasis. Even if the tumor is big and metastasized to the lymph node, it could still be removed by surgical means to save the patient, so the survival rate is not affected by this. However the result, it is still possible to say that both p53 and/or Ki-67 could be warnings for close observation.View full abstractDownload PDF (8318K) -
Dai NAGASE, Kazuo MATSUI, Hideki TAKEMURA, Tetuaki KUBOTA2003 Volume 63 Issue 2 Pages 211-221
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSOne of the greatest concerns among otologists is the countermeasures agaimst readhesion of the new ear drum after tympanoplasty in adhesive otitis media. We think it is important to facilitate early regeneration of the middle ear mucosa, as well as to assure aeration in the middle ear cavity immediately after operation. For this reason, in patients with ear drum adhesion we attempt to minimize exposure of the middle ear bone surface as much as possible. However, in some patients with extensively exposed bone surface in the middle ear cavity, we transplant mucosa of the inferior turbinate to the bone surface to facilitate epitheliazasion. To investigate the morphological findings of the transplanted inf erion turbinate, we obtained biopsy specimens at the second stage operation. From May 1993 to December 2000 we performed nasal mucosa transplantation on 45 cases of the ear with adhesive otitis media: thirty-one cases of cholesteatoma with adhesive otitis media and fourteen cases of postoperative ear (20 males, 25 females) . The method of operation was canal wall down typanoplasty with canal reconstruction using auricular cartilage. Usually nasal mucosa grafts are placed on the promontrium. Among the 45 cases, 16 cases were carried out by single-stage surgery and the remaining 29 cases, by staged surgery. Four cases experienced recurrence of adhesion. No recurrent cholesteatoma occurred in al cases during the follow-up period. At the second stage operation, we obtained biopsy specimens of the middle ear mucosa, where the nasall mucosa was transplanted. We investigated the morphological findings of 24 cases; 5 cases could not be investigated because the biopsy speciments were too little. 50% was pseudostratif ied ciliated columnar epithelium which is similar to nasal mucosa. Glandular tissue could be seen under the epithelium in 13 out of 24 cases. Among most of the 13 cases, glandular tissur decreased in quantity and atrophic findings could be seen as well. We consider that nasal mucosa adapts to the middle ear environment and survives at a high rate. It is considered that this operative method is useful for preventing the recurrence of adhesion by securing the middle ear cavity.View full abstractDownload PDF (15116K) -
Hajime HANAOKA, Tetsuaki KUBOTA, Yoshiyuki KADOKURA2003 Volume 63 Issue 2 Pages 222-230
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn the field of head and neck surgery, when a trachea is removed in a large area, reconstruction of the trachea using an artificial trachea is carried out. One characteristic of this collagen is that the mucous membrane regenerates. We researched histologically and electoronmicroscopically cellular regeneration when an artificial trachea is rebuilt using the collagen of a rabbit. The rabbit was anesthetized and its trachea was exposed. We operated on the tracheal incision, 5 mm×10mm in size. Subsequently, a large amount of collagen was fixed on a collagen sheet. Collagen fibers were observed on the collagen sheet in the extraction trachea after one week. The surface of the collagen sheet was not covered with ciliated epithelium. Connective tissues were made on the collagen sheet after two weeks. Basal membranes, basal cells and ciliated cell were extended from the trachea incision side of the connective tissue. After three weeks, ciliated cells and brush cells were observed on the collagen sheet. Four weeks after transplantation, the surface of the collagen sheet was covered with ciliated epithelium, and the tracheal structure was nearly normal. The collagen sheet gradually dissolved, was absorbed, and in the 12th week put on the connective tissue. The collagen sheet we developed may be an effective method to reconstruct an artificial trachea.View full abstractDownload PDF (13150K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2003 Volume 63 Issue 2 Pages 231-233
Published: April 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (382K)
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