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Volume 41, Issue 1
Displaying 1-10 of 10 articles from this issue
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Kazumasa YASUMOTO, Yutaka INADA1981 Volume 41 Issue 1 Pages 1-6
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe have performed a clinical study to analyse the cause of postoperative hypoxemia in patients who underwent upper abdominal surgery under general anesthesia by measuring A-aDO2 and a-ADN2 before and after operation. It is regarded that a-ADN2 is a most reliable index of unequal distribution of ventilation-perfusion rations in the lung. And the effect of pain relief by epidural injections of 2 mg morphine upon arterial blood gas and pulmonary function (spirometry, flow volume curve and single-breath nitrogen test) was examined after upper abdominal surgery.
PaO2 decreased and at the same time A-aDO2 and a-ADN2 increased on postoperative days. These changes were more remarkable in the aged patients. We presumed that the unequal distribution of ventilation-per-fusion rations in the lung played a role in the fall of postoperative PaO2, considering that both A-aDO2 and a-ADN2 increased in parallel after operation.
We have succeeded in reducing the postoperative hypoxemia by epidural injections of morphine. It is thought that this phenomenon is due to preventing FRC to decrease on postoperative days by pain relief.View full abstractDownload PDF (509K) -
[in Japanese]1981 Volume 41 Issue 1 Pages 7-14
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (777K) -
Kenji MATSUMURA, Hirotsugu IDE, Sadahiro HASHIMOTO, Shogo ITOH1981 Volume 41 Issue 1 Pages 15-25
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSRabbits premedicated daily for 3 weeks by the combination of steroid hormone and insulin were inoculated with bile or liver homogenate obtained from the patients with type A hepatitis and non-toxic fluminant hepatitis.
Premedicated rabbits were divided into 4 groups according to inoculation samples.
I group ; bile from type A hepatitis patients.
II groups : bile from fluminant hepatitis.
III group : liver homogenate from fluminant hepatitis.
VI group : homogenate from rabbit liver, induced tissue lesions by inoculation in above group. Rabbits were sacricefied 4, 10, 14 and 22 days after inoculation, respectively.
Histological findings were characterized by multifocal cell necrosis, particularly in the para-lobular areas and infiltration of polymorphonuclear leucocytes, with part of the mononuclear cells surrounding the sites of cell necrosis and focally in the potal areas. These findings were observed in five cases in eleven rabbits, in group I, 4/5 in group II, 1/4 in group III, 5/13 in group VI.
No cytoplasmic inclusion bodies were detected in hepatocytes by the Orcein staining method. No virus-like particles were detected in cytoplarm or nucleus of hepatocytes by electronmicroscopic analysis.View full abstractDownload PDF (13006K) -
Takayuki MATSUKI, Tadanao KIMURA, Seiichiro INOKUCHI1981 Volume 41 Issue 1 Pages 27-37
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMyofibrous organization of the M. tibialis anterior of 20 adult rats (10 males and 10 females) which were subjected to fasting from 3 to 21 days, were examined and compared with controls.
Following results were obtained.
1. The thickness order for each type of muscle fiber was largest in white, then in intermediate, and in red, fiber in fasted rats. But the differences of size and S. D. in each muscle fibers were smaller than in controls, and the super large white fibers which were always present in controls, were not present in experimentals.
2. Decrease rate of muscle fiber size was larger in white and red than in intermediate, and was larger in female than in male. Comparing to the decrease rate of body weight, that of fiber size was remarkable at the primary stage of fasting, and this tendency was distinct in white and red fiber among the three types.
3. Muscle fiber size was generally larger in males than in females in experimentals as in controls, but the number of subjects, without sex difference of muscle fiber size, was large in white, then intermediate and smaller in red, in contrast to controls.
4. The muscle fibers were darker by Sudan Black B staining in experimentals than in controls at the later stage of fast (after 14, day) . On the other hand, it was possible to differentiate the 3 type of muscle fibers, and the distribution of the 3 types of muscle fibre in a cross-sectional area was equal to those of controls.View full abstractDownload PDF (2805K) -
Yuichiro MIYAZAKI1981 Volume 41 Issue 1 Pages 39-45
Published: February 28, 1981
Released on J-STAGE: November 19, 2010
JOURNAL FREE ACCESSThe potent circulatory effects of pentazocine have been investigated, and it is known that it may effect on the sympathetic nervous system of vascular smooth muscles. In the isolated mouse vas deferens, which are richly innervated by adrenergic nerve fibers, the effects of pentazocine on adrenergic transmission were studied and following results were obtained.
(1) On transmural stimulation (10HZ) biphasic mode (twitch-like and tetanus-like) of contraction was observed. Pentazocine (10-7M-3×10-5M) potentiated tetanus-like contraction dosedependently.
(2) The contraction produced by stimulation of norepinephrine (NE) (8×10-7M) was not potentiated by pentazocine (3×10-6M) .
(3) On the study of the overflow of 3H-NE (2×10-7M, 15Ci/mM), pentazocine (10-7M-10-5M) had no effect on stimulation-induced overflow, but induced augmentation of the basal overflow dosedependently.
These results of experiments suggested that pentazocine pontentiated the sympathetic tone of the vas deferens. And increased spontaneous release of NE. The cumulative effects of NE released both spontaneously and by stimulation might produced the sympathomimetic effects of pentazocine.View full abstractDownload PDF (1649K) -
THE ETIOLOGY OF PROFOUNDLY RETARDED PERSONS LIVING AT HOME IN THE METROPOLIS OF TOKYOYasunori MOCHIZUKI1981 Volume 41 Issue 1 Pages 47-56
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn 86 profoundly retarded adults living at home, the very large (19.3 %) inbreeding coefficient was found among their parents and the morbidity was as small as 4.5 % among their brothers and sisters. The largest morbidity (38.1 %) was found with the first children, and it deceased according to the birth order. The smallest morbidity (18.8 %) was found with the fifth-birth children, however, the morbidity tended to be larger with the sixthbirth and less (30.0%) . As much as 26 of them were injured during the pre-natal period, including nine of hyperemesis gravidarum with serious malnutrition. Thirty-six of them were injured during the pen-natal period, and 16 of them suffered from neonatal asphyxia.
Of the 86 retarded persons, 53 were congenital, 32 were acquired and one was unidentified. Out of the 53 congenital persons, six were Down's syndrome, six were congenital hydrocephalus, two were congenital microcephaly, one was West's syndrome and 38 were unidentified; two of the unidentified might be of physiologically mentally retarded. The direct causes of the acquired retardation were infection (24), head injury (3), epilepsy (3), malnutrition (1) and unidentified (1) .View full abstractDownload PDF (1427K) -
—Polluted rat lung after long term inhalation of heavy oil combustion product—Kosuke NOZAKI, [in Japanese]1981 Volume 41 Issue 1 Pages 57-64
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSRats of SPF origin were continuously exposed to a moderate concentration of heavy oil combustion product during their life-span.
Typical anthracosis of the lung and of the thoracic lymphnodes, pharyngitis, bronchitis, panbronchiolitis, thickening of the alveolar wall with slight fibrosis and early sign of emphysema, were more or less prominent in the respiratory tract after long-term exposure. Those pictures were rather similar to that of polluted lungs in the aged urban inhabitants. Bronchitis and bronchiolitis were associated with unusual proliferation of the epithelium associating adenomatous hyperplasia, which persisted throughout the life-span of the animals. Small microscopic foci of peripheral squamous cell metaplasia were noticed in 2 out of 10 animals, however, no case of pulmonary cancer was found.
Elimination of the particulate matter from the combustion product resulted in almost complete disappearance of the above mentioned respiratory lesions throughout the whole life-span of the animals.View full abstractDownload PDF (4538K) -
Masachika TSUJI1981 Volume 41 Issue 1 Pages 65-75
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSASO (antistreptolysin O), ASK (antistreptokinase), AHD (antihyaluronidase), SZ (streptozyme test), and Blue ASO titer were determined in paired specimens taken from 80 inpatients with scarlet fever. The sera were collected from patients three times at intervals in group 1 with a combination of ASO, ASK, AHD (23 cases) and SZ, while in 40 patients of group 2, with the combination of ASO, ASK and Blue ASO, respectively. The following results were obtained, in group 1, titers were found elevated, 55.0%, 42.5%, 45.0% and 17.4% of the cases in ASO, ASK, SZ and AHD respectively, whereas in the group 2, 47.5%, 42.5% and 75.0% of cases were elevated in ASO, ASK and Blue ASO, respectively. When ASO was determined in conjunction with ASK, AHD and SZ, the titers were elevated in 78.3% of the cases in group 1; whereas, when ASO, ASK and Blue ASO were combined and tested in group 2, 80.0% of cases were elevated. Blue ASO titers rose in the early stage of infection, and indicated an effective method for diagnosis of a disease with a short period of illness, such as scarlet fever. Diagnostic value of serological tests for scarlet fever will be increased by combining these plural tests.View full abstractDownload PDF (1065K) -
Satoru SUZUKI, Shizuo FUJIMORI, Michinari OKAMOTO, Michihiko KIMURA1981 Volume 41 Issue 1 Pages 77-80
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDiagnosis of sudden deafness is easy, but we observed two cases of psychogenic hearing loss while testing for and treating sudden deafness.
Case 1: A 23-year-old woman was deaf in the left ear, but during the period of treatment, the deafness transferred from the right ear to the left one.
Case 2: A 17-year-old woman was deaf in both ears. We found that we had made a mistaken diagnosis during our medical treatment of her, so we gave her psychogenic treatment. This form of treatment had no effect, but the deafness in both ears improved after the traffic accident.View full abstractDownload PDF (1504K) -
Takanori SUGIUCHI, Mikio KANDA, Hideo NAMIKI1981 Volume 41 Issue 1 Pages 81-89
Published: February 28, 1981
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA case of a 68-year-old Caucasian man who developed liposarcoma on his inner upper thigh is presented. For the diagnosis of liposarcoma, it is important to recognize other types of mesenchymal malignancies. A variety of lipogenic tumors, and, classification and clinicopathologic correlation of liposarcomas are discussed.View full abstractDownload PDF (13509K)
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