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Volume 46 (1986)
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Volume 46, Issue 2
Displaying 1-18 of 18 articles from this issue
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[in Japanese]1986 Volume 46 Issue 2 Pages 169-171
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (2472K) -
1. HUMAN AND CRAB-EATING MONKEYYuji MATSUMOTO, Iwao SATO, Satoshi ONDA, Kenro YASUMURO, Seiichiro INO ...1986 Volume 46 Issue 2 Pages 173-181
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe myofibrous organization of the laryngeal muscles of the human and the macaques were investigated for the morphological analysis of the correlations between the vocalization and the laryngeal muscles. Materials and methods : The materials were obtained from the 4 adult human and 4 crab-eating macaques. The materials were embedded in gelatine and stained with Sudan Black B. On the transverse section of the muscle belly, the number, the size, the density and the type of the muscle fibers were investigated. Results : 1. On the number of muscle fibers of human laryngeal muscles, that of the arytenoideus muscle and the cricothyroideus muscle were the largest, and those of the epiglotticus muscles were the smal-lest. 2. On the fiber size of the human laryngeal muscles, that of the epiglotticus muscles were the largest and the thyreoarytenoideus muscle showed the secondmost size. Within the rest of laryngeal muscles, the arytenoideus muscle showed the smallest size of the fibers. 3. On the muscle fiber density of human laryngeal muscles, that of the epiglotticus muscles show-ed the remarkable low density. 4. Each laryngeal muscle in human contained about 40% white fibers, about 35% red fibers and about 25% intermediate fibers, respectively. 5. The macaques lacked the epiglotticus muscles. The number of the muscle fibers and the size of muscle fibers of each laryngeal muscle of the macaques were smaller than that of human. Above all, the differences observed in the arytenoideus muscle and the cricothyroideus muscle between the human and the macaques were remarkable. And the percentage of the white muscles fiber in the each laryngeal muscle of macaque were higher than that of human. 6. On compare to human, the muscles which participate the closing of the posterior part in the glottis and the extending, tensing and adducting of the vocal cord are undeveloped relatively in macaque. Consequently, the larynx of macaque is good for the short phonation accompanying the high sound and not good for the continuous and various tone phonation.View full abstractDownload PDF (1063K) -
Tadakatsu OHNAKA1986 Volume 46 Issue 2 Pages 183-188
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe associations of body composition with blood pressure were studied in 2086 men aged from 23 to 58 years working in a factory. Height (H), body weight (W), chest and abdominal girth, skinfolds (triceps, subscapula and abdomen) and systolic (SBP) and diastolic (DBP) blood pressure were measured. Total fatmass (FM) and lean body mass (LBM) were calculated according to the equation of Ohnaka for % Fat. In addition the abdomen to chest girth ratio (A/C ratio) was calculated as an index of abdominal adipose tissue distribution. Quetelet's index (W/H2) was employed as the body build index.
Significant correlations between blood pressure and each item of the body composition variables studied except for height were observed. Among fatness indices studied, the highest correlation of blood pressure was found with FM. In order to assess the magitude of the influence of body composition variables on blood pressure, multiple regression analyses were performed with FM, LBM and the A/C ratio serving as the independent variables. FM and the A/C ratio were positively correlated with both SBP and DBP. LBM, on the other hand, was negatively associated with blood pressure when FM and the A/C ratio were taken into account. Among these variables, FM accounted for the largest percentage of explained variance in both SBP and DBP. These findings suggest that body fat mass may be important in the relationship between blood pressure and body composition.View full abstractDownload PDF (666K) -
Setsu SHIMANOUCHI1986 Volume 46 Issue 2 Pages 189-201
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSFor 69 patients whose home care services were begun between 1975 and 1983 by the home care group of Tokyo Metropolitan Neurological Hospital, related data were gathered including the patient's property, social environments, symptoms and disorders, progression, ADL, mental ability, and actual status and difficulties in care. A control group included both bedridden and ill, non-bedridden elderly persons. The study revealed the following : (1) The Parkinson's disease patients received care at home included first or second degree physically handicapped 28 patients (40.6%) . Remarkably reduced ADL and some disorders of communication were found in all the cases, while mental symptoms, dementia, and mental disorder such as enervation were noticed in most cases. (2) The symptoms or disorders which are ex-pected to be improved by home care are dysuria, dysphagia, mental symptoms and so on. The above mentioned symptoms and disorders had been improved through intubation feeding, urinary bladder indwelling catheterization etc. (3) The frequency and severity of the symptoms and disorders, the necessity of treatments, and difficulty in home care were significantly greater for the Parkinson's disease patients than for the bedridden control group. (4) The medical care as well as social needs of nursing, expenditure of life, and medicine, family health control are necessary in home care activities.View full abstractDownload PDF (1652K) -
Sawako KAWAMURA1986 Volume 46 Issue 2 Pages 203-213
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTokyo Metropolitan Neurological Hospital has begun home care service since 1974 for neurological intractable patient. This study was epidemiologically researched concerning public health nursing of 43 cases of Amyotrophic Lateral Sclerosis within the intractable patients (347 cases) through the home care service. The author collected to analysis data of medical and public health nursing records and hearing particularly. The results are following, 1) 29 cases of 43 Amyotrophic Lateral Sclerosis cases were death case in this data. And, such 29 death cases showed sex ratio (males : female) 1.69, average age of onset 52.7 years old, and bulbar sign of initial symptoms 20.9%. 2) The average duration of survibed life from onset was 4.4 years. And also, the death cases which had provided adequated home care showed the longer average duration. 3) Such medical home care and public health nursing was proved much more effectiveness for the sake of utilizing hospital beds and promoting wellfare of patient and family. 4) The home care and public health nursing has been developed through organized community efforts, specially Tokyo Metropolitan Neurological Hospital services. 5) It was significantly important for author to evaluate the home care system of neurological intractable disease included other chronic-progressive patient, bedridden elder person and physically handicapped person had much more effectiveness.View full abstractDownload PDF (1439K) -
Masaru MATSUDA, Toshihiro TAKABA, Koichi INOUE, Seirou NOMOTO, Hideo Y ...1986 Volume 46 Issue 2 Pages 215-225
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSFifty patients undergoing mitral valve replacement were studied during operation by measuring the duration of extra-corporeal circulation and, after operation, by hemodynamic measurements and determinations of myocardial enzymes (total CK, CK-MB, GOT) . Myocardial protection was accomplished by topical cardiac cooling only in 10 patients (group I), crystalloid glucose-potassium cardioplegia with topical cardiac cooling in 20 patients (group II), and oxygenated crystalloid cardioplegia (St. Thomas solution) with topical cardiac cooling in 20 patients (group III) . Total extra-corporal circulation time and aortic clossclamp time were the longest in group III, and the difference between group I and group III were seen (p<0.01) . As the enzymic activity increased postoperatively in all groups, there were no significant difference in each groups. Cardiac Index were maintained over 2.01/min/M2 in all groups during postoperative period in ICU, however, high left atrial pressure and multidose administration of catecholamine were needed in group I to keep the constant cardiac output, on the other hands, good cardiac output were maintained in group III at low left atrial pressure. Early postoperative cardiac function was the best in group III and the worse in group I. As cardioplegia showed good myocardial protective effects, oxygenated crystalloid cardio-plegia reduced ischemic myocardial injury and permitted better functional recovery. Oxygen-ated crystalloid cardioplegia provides superior protection for mitral valve replacement.View full abstractDownload PDF (1237K) -
Sadao NAKAYAMA, Taiki TSUJI, Kenichi USAMI1986 Volume 46 Issue 2 Pages 227-235
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe acute toxicity of carboxyethylgermanium sesquioxide (Ge-132) was studied in ddY mice and Wistar rats. Test drugs were prepared as 0.5% carboxymethylcellorse suspension (Ge-132-CMC suspension) and 60% solution in distilled water at pH 7 containing sodium hydrogen carbonate (Ge-132-pH 7 solution) . Drugs were administered orally, subcutaneously, intraperitoneally and intraveneously. The LD50values of Ge-132-CMC suspension were estimated 11, 950mg/kg, p.o., 7, 805mg/kg, s.c. and 21, 70mg/kg, i.p. in mice and 11, 350mg/kg, p.o., and 3350mg/kg, i.p, in rats. The LD50value of s.c. administered Ge-132-CMC suspension in rats was not estimated for the outflow of this suspension from administration site. The LD50values of Ge-132-pH 7 solution were estimated 11, 600mg/kg, p.o., 12, 350mg/kg, s.c.. and 5, 720 mg/kg, i.v. in mice and 10, 050mg/kg, p.o., 17, 050mg/kg, s.c. and 4, 590mg/kg, i.v. in rats. LD50values of Ge-132-pH 7 solution i.v. administration in mice and rats were a larger than Ge-132-CMC suspension i.p, administration. In each route administered Ge-132, the mice and rats revealed the toxic signs such as writhing, decrease in spontaneous movement, loss of righting and withdrawal reflex and inhibition of respiration. In addtion to, the mice and rats administered Ge-132-pH 7 solution died after showing opisthotonus and tonic convulsion, subcutaneously administration of Ge-132-CMC suspension caused the corrosion and necrosis of subcutaneous. From these results, it was suggested that the acute toxicity of Ge-132 in mice and rats was lower.View full abstractDownload PDF (915K) -
Yutaka HARA, Kumiko HIRATO, Masakazu SEKI, Takumi YANAIHARA, Tetsuya N ...1986 Volume 46 Issue 2 Pages 237-242
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSClinically, Dehydroepiandrosterone-sulfate (DHAS) has been used to ripen uterine cervix. In order to clarify the mechanism of direct effect of DHAS on human uterus, an attempt was made to find DHAS specific binding protein in human uterine cytosol. Myomerium were obtained from the patient with uterine myoma at hysterectomy, pulverized and homogenized. Cytosol fraction was obtained by centrifugation at 105, 000xg for 60min. After removal of intrinsic steroids with 0.5% DCC, cytosol was added with 100M3H-DHAS and incubated for 12hours. Perotein bound 3H-DHAS was separated from free3H-DHAS by Sephadex G-25M gelfiltration. All procedure were performed at 4°C. Two radioactive peaks were found ; one at Fr. No. 17. and the other at Fr. No. 50. The first peak was considered to be protein bound since the fraction was studied by addition of excess amount of steroids in incubation system. An addition of DHAS binding, percent binding of DHAS was not altered by the addition of estradiol, progesterone (P4), 20-α-OH-P4, DHA and dihydrotestosterone. Inhibitory effect of DHAS was dose dependent.14C-DHAS incubated with myometrial cytosol for 2 hours at 37C°was recovered as unchanged form, indicating that the radioactive peak found in protein fraction was DHAS. From the results obtain above, it is suggested that cytosol of human myometrium possess the capacity to bind DHAS specifically.View full abstractDownload PDF (574K) -
Kazuhide KUMAGAI, Akira YASUI, Yoshiaki NISHIDA, Makoto NAKAJIMA, Hiro ...1986 Volume 46 Issue 2 Pages 243-248
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn the diagnosis of the cancer volume of the depth of invasion of the depressed carcinoma by macroscopical finidngs, the analysis of the characteristics of the depressed floor is very important, classed with the form of cancer edge and the hardness of the cancer lesion.
The majority of the depressed carcinoma have the ulceration in the lesion. Prof. Murakami observed the healing of the malignant ulceration, and called the“Malignant cycle”such a phenomenon. By the rise and fall of the ulceration in the cancerous lesion, the depressed floor showed all kinds of morphological change.
Our purpose of this study is the investigation of the relationship between the depth of invasion and morphological status with the ulecration in the cancerous lesion.
The objects were 31 depressed type gastric carcinomas with the ulceration studied in our institute. The comparative study was carried out between macroscopical and microscopical findings.
The resuts were as follows;
1. The cases in mucosal cancer showed the regular granular pattern on the depressed floor.
2. The Borrmann type 2 or 3 showed the rough nodule or hard flat structure on the floor.
3. In the submucosal carcinoma, the case of minimum invasion to submucosal layer, showed regular granule like mucosal carcinoma and the case of mass invasion showed rough nodule like advanced carcinoma.
In the type IIc like advanced carcinoma, according to the cancer volume of the proper muscle layer, the finding of depressed floor changed the granular pattern to a rough surface.
If there is a relationship between the healing course of the malignant ulceration and cancer invasive volume below the submucosal layer, the finding of the depressed floor shows a good indication for diagnosis of the depth of invasion. In the future, we have to carry out more comparative studies between the macroscopical and microscopical findings.View full abstractDownload PDF (3939K) -
Hironobu OHONE1986 Volume 46 Issue 2 Pages 249-259
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA clinico-statistical survey was carried out on 184 cleft lip patients (unilateral 139, bilateral: 45) who had undergone the primary operation by Onizuka's method at the Department of Plastic and Reconstructive Surgery, School of Medicine, Showa University during the 3, 5-year period from April, 1980 to September, 1983.
1. Keloid formation was seen on 37 cases (26.6%) of unilateral cleft lip, 6 cases (13.3%) on first and 21 cases (46.7%) . on second operations of bilateral cleft lip.
2. Keloid formation was found more on right unilateral cleft lip than on the left.
3. Keloid formation was found more on the incomplete unilateral cleft than lip the complete type.
4. It showed high percentage of much more severe and serious keloid formation on cleft lip in conjunction with cleft palate. One of the factors for its cause is the nasal escape of food, etc.
5. There was no difference between male and female on the ratio of keloid formation.
6. We evaluated the effect of radiation therapy on cleft lip patients who had primary repair, and found that it was not effective to prevent the keloid formation from the primary repair of cleft lip.View full abstractDownload PDF (1060K) -
Shoji IGAWA1986 Volume 46 Issue 2 Pages 261-268
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWeight control technique, especially the methodology for weight reduction, have been an important problem to be solved for the athletes of weight-in-system sports. This study was carried out to obtain the reasonable method of the rapid weight reduction by diet and physical training. Ten wrestlers, whose body weight should be reduced about 10% in a short period of time, were served as subjects. Some blood and urine components were analyzed, and physical and nutritional measurement were performed. Following results were obtained from these data. For the rapid weight reduction in 7 days, body weight, lean body mass and body fat mass decreaed 5.55kg (8.5%), 4.56kg (7.7%) and 1.00kg (15.4%) . The physical work capacites in endurance run (1500m), muscle strength and maximal power during knee extension were not affected by weight reduction. Excretion of urinary nitrogen and 3-methylehistidine did not change during reduction period. Hemogrobin, hematocrit and MCHC were not affected, but total plasma protein was reduced. Free fatty acid was significantly elevated. The results suggest that the rapid weight reduction using a combination of exercise and diet induces to increase fat utilization and to decrease protein utilization.View full abstractDownload PDF (810K) -
Hiroshi KAJIYAMA, Hideharu OHARA, Hidekazu OTA, Koji TASHIRO, Akira MI ...1986 Volume 46 Issue 2 Pages 269-278
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSAdjuvant activity of DNP-Ficoll was found in culture system using SRBC-primed spleen cells (or B cells separated from the activated spleen cells) . The spleen cell suspensions were cultured for 48 hr at 37°C after addition of DNP-Ficoll, and then, the number of antiSRBC PFC was determined by the method of Cunningham and Szenberg. When the spleens excised from ICR mice 4 and 6 days after immunization with SRBC antigen were used, increase in anti-SRBC (IgM) PFC number was observed in the cultured cells in the presence of DNP-Ficoll (0.02μg/ml) . The values from the treated and control cultures were 351±29.0 and 240±23.8/106B cells, respectively. This adjuvant material did not affect production of soluble factors from T cells or macrophages. Only when B cell and T cell co-existed with macrophage in the culture, we have obtained increased number of PFC nearly equal to that in ICR mouse spleen cells.View full abstractDownload PDF (1188K) -
Takehiko GOKAN1986 Volume 46 Issue 2 Pages 279-283
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe effects of brain irradiation on the enzyme activity of MAO and the level of catecholamine were examined in whole brain of male rat. They were determined immediately after, 1, 2, and 3 hours after irradiation of60Co γ ray. After irradiation of 1000 rad, MAO activity was significantly increased. However, no significant change was found after irraaiation of 500 and 2000 rad. The catecholamine level did not change significantly after exposure to 1000 rad of60Co γ ray. These results may that indicate increased MAO activity caused no significant change of catecholamine level because its level was regulated by the rate of not only degradation by MAO but also catecholamine synthesis. In 1000 rad irradiation, MAO was much activated by using β-phenylethlamine (β-PEA) than serotonin as substrates. This represents MAO-B was much activated than MAO-A, because β-PEA is specific substrate of MAO-B and serotonin is that of MAO-A. This result may represent MAO-B is much affected py free radical of irradiation because MAO-B is situated closer to peripheral hydrophoric region than MAO-A.View full abstractDownload PDF (597K) -
THE COMPARATIVE ANALYSIS OF THE FORMER AND THE LATTER 5 YEARSRyushi MARUTANI, Susumu SAITO, Hiroyuki OKUMO, Saiji KONDO, Hiroumi SU ...1986 Volume 46 Issue 2 Pages 285-290
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe analyzed the 1015 of pediatric orthopaedic admittances of the Fujigaoka hospital from July, 1975 to June, 1985. Fujigaoka hospital was opened at Midori-ku, Yokohama-shi in July 1975 and we had the 10th anniversary of our hospital this year.
From July 1975 to June 1980, the former 5 years, we had 206 boys and 180 girls admittances. From July 1980 to June 1985 the latter 5 years, we had 363 boys and 264 girls admittances. The former 5 years, the most common diseases are congenital dislocation of the hip, transient synovitis of the hip and supracondylar fracture of the humerus. The latter 5 years, they are transient synovitis of the hip, supracondylar fracture of the humerus and Legg-Calve-Perthes disease.
We investigated the number of admittances, the change of diseases, the distribution of admittances and so forth in former and latter 5 years.View full abstractDownload PDF (628K) -
Tadashi IGARI, Toshiaki HASHIMOTO, Kazuhiko ISHII, Masaaki NISIDA, Tos ...1986 Volume 46 Issue 2 Pages 291-293
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSReport is made on one case who showed the generalized convulsion by the administrasion of anti-depressant, Maprotiline.
The patient, 46 years old male, showed the intermittent depressive state. On the 19 day, after starting the administration of 75mg/day of Maprotiline, he showed the generalized convulsion. The treatment was suspended. He was examined with measurement of serumlevel of Maprotiline, EEG, cranial CT, blood, urinary tests, EEG activated with bemegride, then, it was considered to be a transient acute intoxicasion with Maprotiline. Therefore, it seems necessary to grasp the latent abnormality of cerebral function in the treatment with antidepressants for depressive cases.View full abstractDownload PDF (322K) -
Hisao NISHIJIMA, Itsuo TADAMA, Masuhiro TOYOTA, Toshiaki HASHIMOTO, Ka ...1986 Volume 46 Issue 2 Pages 295-298
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSOne case of general paralysis hardly encountered due to the treatment with penicillin is reported. The patient is 44 years old male, and his sexual intercourse is rather frequent, but its volition has been reduced since the age of around 35, then, he was admitted in our hospital with the chief complaints of headache, dysarthria and reduced calculating power. By the neuro-psychiatric findings such as syllable stumbling and dementia as major symptoms as well as positive serological test for syphilis of spinal fluid, the patient was diagnosed as general paralysis. There was no abrnomal findings on EEG and cranial CT, however, no improvement was observed on the decrease in level of personality and dementia as major symptom. Although the symptom of general paralysis has been gradually reduced, the mechanism of etiology is still an insoluble problem.View full abstractDownload PDF (1689K) -
Toshiyuki SUDO, Junji OKAZAKI, Koumei CHINO, Masahiro OHNAKA, Mitsuru ...1986 Volume 46 Issue 2 Pages 299-302
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMeniscus ganglion is an uncommon disease. We reported two cases. Case 1: a 29-year-old male, medial meniscus ganglion in the right knee joint. Case 2: a 40-year-old famale, lateral meniscus cyst in the left knee joint.
In Japan 73 cases have been reported as far as we examined. Of those 73 cases only 54 have been recorded in detail. W e examined those 54 cases with our two cases. Male cases were 34 and femals 22, The age ranged from 6 to 57. In 37 cases they located on lateral meniscus, in 19 cases on medial meniscus. 16 cases had the history of the trauma. 27 cases had none and 13 cases were not clear whether they had trauma or not. The meniscus ganglion is operated by three methods; extirapation of both cyst and meniscus, extirpation of a part of meniscus and extirpation of cyst only. In 38 patients both cyst and meniscus were extirpated. In one patient cyst with a part of meniscus was extirpated. In 5 patients only cyst was extirpated, In 12 patients had no records of the methods. None of the patients had a relapse. We think that the best radical operation is to extirpate both cyst and meniscus.View full abstractDownload PDF (2189K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1986 Volume 46 Issue 2 Pages 303-313
Published: April 28, 1986
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (1365K)
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