Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
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Volume 70, Issue 1
Displaying 1-15 of 15 articles from this issue
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Feature Articles: The Goal of the Therapy of Diabetes Mellitus
Final Lecture
Special Material
Educational Material
Original
  • RELATION BETWEEN THE WIDTH OF THE ALVEOLAR CLEFT AND GROWTH CHANGES IN THE MAXILLARY DENTAL ARCH IN CHILDREN WITH BILATERAL CLEFT LIP AND PALATE
    Maki NODA, Yoshiaki HOSAKA, Akikazu UDAGAWA, Hiroyuki SUZUKI, Hitomi K ...
    2010 Volume 70 Issue 1 Pages 82-89
    Published: February 28, 2010
    Released on J-STAGE: May 27, 2011
    DOIhttps://doi.org/10.14930/jsma.70.82
    JOURNAL FREE ACCESS
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    One of many factors involved in determining the prognosis of surgery on cleft palate is the severity of the original alveolar cleft. We compared the relationship between the width of the alveolar cleft and growth changes in the maxillary dental arch in children with bilateral cleft lip and palate using a maxillary dental cast. The subjects were 10 patients treated for bilateral cleft lip and palate from whom an appropriate maxillary dental cast taken before palatoplasty and the deciduous dentition period. The patients were divided into two groups and subsequently compared. One group (group A) was comprised of five patients, each with a total bilateral alveolar cleft width of 10 mm or less. The other group (group B) was comprised of five patients, each with a total cleft width of more than 10 mm. Before palatoplasty, group B showed significantly lower anterior alveolar widths than group A, but no obvious differences were observed for the posterior alveolar width, anteroposterior diameter, and anterior anteroposterior diameter. In the deciduous dentition period, no clear differences in any of these parameters were found between the two groups. The present study indicated that the width of the alveolar cleft has little effect on growth changes in the maxillary arch.
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  • INFLUENCE OF SUBJECT-PERFORMED TASKS ON MEMORY IN HEALTHY INDIVIDUALS USING fMRI STUDY
    Comparison of Verbal Tasks with Subject-performed Tasks
    Hitomi KOBAYASHI, Keiko SEKI, Masaru MIMURA
    2010 Volume 70 Issue 1 Pages 90-96
    Published: February 28, 2010
    Released on J-STAGE: May 27, 2011
    DOIhttps://doi.org/10.14930/jsma.70.90
    JOURNAL FREE ACCESS
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    The subject-performed tasks (SPT), in which an individual actually performs presented actions while learning, is known to be associated with better recall as compared to verbal learning of action sentences. Such superiority of the SPT or the enactment effect is believed to result from a multi-modal encoding process; however, its mechanism still remains unclear. In this study, to examine the neural basis of the SPT effect, brain activation during recognition phase of the task was evaluated using functional magnetic resonance imaging (fMRI).
    Eight right-handed healthy individuals participated in the study. The participants learned action sentences under two learning conditions, i.e., verbal tasks (VT) and SPT. In VT, the participants orally read and learned the sentences. In SPT, the participants performed each action with an object. The 1.5 T GE SIGNA MRI was used and EPI BOLD images were obtained during the recognition phase.
    The left retrosplenial cortex activation was observed while the participants were recognizing the verbally learned materials. From this result, the left retrosplenial cortex appeared to be associated with the processing of memory generation. In contrast, the bilateral motor cortex and the left supramarginal gyrus were activated during the recognition phase of materials learned under SPT. The bilateral motor cortex observed in SPT suggests that these regions associated with motor information, presumably with tactile and spatial information, were stronger as a result of SPT, leading to greater activation of the above mentioned motor-related areas during the recognition phase. In addition, we found greater activation of the supramarginal gyrus during recognition of SPT-encoded material compared with VT. Results support the findings by Russ et al, 2003, and such a specific activation pattern for enactment may suggest complex multi-modal associative processing of SPT.
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Case Report
  • AN AUTOPSY CASE REPORT; PRIMARY SYNOVIAL SARCOMA OF THE LUNG
    Miki NYUI, Masafumi TAKIMOTO, Yoshihiro UMEMURA, Hidekazu OTA, Kentaro ...
    2010 Volume 70 Issue 1 Pages 97-104
    Published: February 28, 2010
    Released on J-STAGE: May 27, 2011
    DOIhttps://doi.org/10.14930/jsma.70.97
    JOURNAL FREE ACCESS
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    We report a rare case of primary synovial sarcoma of the lung. The patient was a 35-year-old male complaining of a bad cough, slight fever and back pain. Chest radiograph and computerized tomography scan showed an abnormal infiltrative shadow in the right upper lobe of the lung. Histologically, the tumor of a lung biopsy specimen showed a dense proliferation of short spindle cells. However, a specific diagnosis could not be made even with immunohistochemical examination because the spindle cells expressed no specific feature. We diagnosed a non-epithelial malignant tumor (spindle cell sarcoma) of the lung at the time. After radiation therapy, the tumor decreased to half the size. However, the tumor enlarged again after a few months. Subsequent radiation and chemotherapy had no effect, and the patient died after one year and nine months. From the tumor tissues at autopsy, we examined for the presence of SYT-SSX fusion gene transcripts by reverse transcription polymerase chain reaction. Because this fusion gene is identified with synovial sarcoma. We were able to diagnose this case as primary synovial sarcoma of the lung.
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