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Successor
Volume 63, Issue 1
Displaying 1-15 of 15 articles from this issue
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[in Japanese]2003 Volume 63 Issue 1 Pages 1-2
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese]2003 Volume 63 Issue 1 Pages 3-6
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese]2003 Volume 63 Issue 1 Pages 7-8
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese]2003 Volume 63 Issue 1 Pages 9-13
Published: February 28, 2003
Released on J-STAGE: November 19, 2010
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[in Japanese]2003 Volume 63 Issue 1 Pages 14-20
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese]2003 Volume 63 Issue 1 Pages 21-25
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
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[in Japanese]2003 Volume 63 Issue 1 Pages 26-29
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
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Misako KOIZUMI, Akira KANDA, Takeshi KAWAGUCHI2003 Volume 63 Issue 1 Pages 30-42
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMore than half of the residents in homes for the aged suffer from incontinence. As a result, training programs based on urination patterns have been developed. However, it is very difficult to determine the urination patterns of aged patients. Our study used a sensing machine to ascertain urination patterns followed by a training program of 41 nursing home residents who had agreed to participate in this study. The urination patterns were determined in 6 out of 25 patients who had been monitored with the sensing machine for 2-3 days; 3 of these 6 were able to control incontinence after undergoing the urination training program. The urination monitor also determined the urination patterns of 9 out of 22 patients who were monitored for 24 hours. In a 3-day survey, urination patterns of 42.2% of the subjects were determined; however, in various 2-day surveys, urination patterns were identified in 23.5 to 85.7% of the participants. These results suggest that, for a successful urination control training program using the sensing machine, it is necessary to identify the urination patterns of the subjects who are free from frequent urination.View full abstractDownload PDF (3320K) -
Fumiyoshi OHYANAGI, Hidetaka AKITA, Hidekazu OTA, Akira SHIOKAWA, Miki ...2003 Volume 63 Issue 1 Pages 43-53
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe most common cancer in Japan is lung cancer. Non-small cell lung cancer represents 75% of all lung cancer cases and are usually associated with poor prognosis. Apoptosis or programmed cell death was first described by Kerret al. Which is one of the most important regulatory mechanisms of cellular homeostasis in organisms. Fas (CD95/APO-1) and Fas ligand (Fast) -mediated apoptosis is one of the main pathways of killer cancer cells in the immune surveillance system. In order to examine whether or not the expression of the apoptosis-related receptor Fas and its ligand has relevance for patient survival, immunohistochemistry was used to analyze the proteins of both factors in 62 cases of non-small cell lung cancer. The Fas expression was high in the adenocarcinoma, was well differentiated, and tended to have a higher proportion in women. Fas Ligand express in the non-small cell lung cancer-like Fas and the expression of Fas ligand have no similar in characteristics. Reganding the combination of Fas and Fas Ligand, the Fas-positive group significantly supressed the tumor size in comparison with the Fas-negative, Fas ligand-positive group. The Fas positive and Fas-Ligand negative groups had a higher incidence of lymph node involvement. The expression of MIB1 was higher in the Fas-negative group than in the Fas-positive group. In this study, we concluded the Fas and Fas Ligand do not haveany significant influence on survival, but apoptosis induced by Fas and Fas Ligand control the tumor size, the incidence of lymph node involvement, and prognosis.View full abstractDownload PDF (3114K) -
Takahiro KATOH, Junko SHINODA, Kazuyuki NAKAGOME, Kunitoshi KAMIJIMA, ...2003 Volume 63 Issue 1 Pages 54-65
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMany reports have suggested cognitive abnormalities in schizophrenia using various psychophysiological and neuropsychological indices; however, there remains a controversy concerning what properties of cognitive function the findings can be related to. Therefore, with the aim of clarifying the issue, we investigated the relationship between psychophysiological indices, such as target P3b amplitude in the oddball task, target P3b and novel P3a in the distraction task; neuropsychological indices, such as the scores of verbal memory, visual memory, and long-term information recall; total scores in WMS-R (Wechsler memory scale, revised), and number of categories completed, and failure to maintain set; perseverative error rates in WCST (Wisconsin card sorting test) and number of trials; and the time to choose the first disc in HANOI (Tower of Hanoi test), all of which had been reported to be markedly impaired in schizophrenia. A comparison between schizophrenic patients (n=24) and normal controls (n=20) suggested that all these indices were significantly impaired in schizophrenic patients, except for the number of failures to maintain set in WCST. Correlation analyses and a principal component analysis revealed that visual memory function, P3b amplitude and WCST indices were closely related, whereas HANOI indices and verbal memory function were somewhat independent from the other indices. Additional correlation analyses revealed significant correlations between P3b amplitude/WCST indices and psychiatric symptom severity evaluated by BPRS (Brief Psychiatric Rating Scale) . These findings indicate that WCST and HANOI, although both are presumed to reflect executive function, are possibly related to distinct cognitive properties. Moreover, a close relation between P3b amplitude and WCST suggest a common underlying factor, “context updating” function, which might also be related to psychopathology of schizophrenia.View full abstractDownload PDF (1400K) -
—Investigation of Preventive and Improving Factors Against Obesity by a Cross-sectional and a Three-year Follow-up Study—Akemi YAGYU, Akira KANDA, Takeshi KAWAGUCHI2003 Volume 63 Issue 1 Pages 66-78
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe prevalence of obesity among Japanese children has been increasing during the past 30 years. As obesity is a high risk factor of atherosclerosis and diabetes, countermeasures to prevent obesity have been carried out at schools. We conducted an epidemiological study to clarify the relationship between obesity and lifestyles of school children. We gave a health examination and a questionnaire to determine food intake and exercise patterns of fourth-grade elementary students in the town of ma. These data were linked to a computer. Three years later a follow-up study was carried out on the same students who were then in the second year of junior high school. The results after the first survey show that those students who suffered from obesity also had significantly higher serum cholesterol levels, hypertension, higher atherosclerosis indices and a higher frequency of liver functional disorders than the non-obese students. The results also proved that lifestyle-related habits such as playing sports after school, minimizing TV watching, eating slowly and chewing foods completely are useful in preventing obesity. The data also showed that obese students whose degree of overweight was over 30% most likely did not pay attention to their eating habits; furthermore, there was a possibility of a discrepancy between the parents and the children regarding the recognition of obesity, the relationship between obesity and lifestyle-related diseases, etc. The results of the follow-up study indicated that an increase of time playing sports was statistically significant on the improvement of the arteriosclerosis index. This study also suggests the role of parents and the cooperation between school children and parents as an important factor in the prevention of obesity.View full abstractDownload PDF (1388K) -
Yoshihiko HAYAKAWA2003 Volume 63 Issue 1 Pages 79-88
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSRespiratory and circulatory conditions, organ blood flow and tissue oxygen partial pressure were examined in adult dogs administered propof of and nitrous oxide to maintain anesthesia. After inducing anesthesia, catheters were inserted to measure various circulatory parameters. Organ blood flows were measured at four points: liver (LBF) ; pancreas (PBF) ; renal cortex (RCBF) ; and renal medulla (RMBF) . Tissue oxygen partial pressure was measured at the liver (PLO2) and kidney (P5O2) . After more than 60 minutes had elapsed following completion of experimental preparation, and breathing and circulatory conditions of subjects had stabilized, parameters were measured as control values (SO) . After collecting SO, subjects were divided into two groups: one administered propofol only (group A) ; the other administered propof of and co-administered nitrous oxide (group B) . For group B, nitrous oxide was used as a respiratory gas, with the fraction of inspired oxygen maintained at 40%, identical to group A. For both groups A and B, 3 mg⋅kg-1⋅h-1 (S3) of propof of was administered, and a second measurement was undertaken 45 minutes thereafter. Administration of propofol was subsequently increased to 5 mg⋅kg-1⋅h-1, then 10 mg⋅kg-1⋅h-1. Measurements were made 45 minutes after each administration (S5, S10) . In group B, mAP, CI, LVdp/dt max, LBF, RCBF, RMBF, PLO2and PRO2decreased significantly. These results suggest that when using propof of to maintain anesthesia with co-administration of nitrous oxide as an analgesic, the dosage of propof of should be limited to a maximum of 5 mg⋅kg-1⋅h-1, to avoid circulatory inhibition.View full abstractDownload PDF (849K) -
Ryuhachiro FUJIMOTO, Toshio MOROHOSHI, Mituru KAWAMURA2003 Volume 63 Issue 1 Pages 89-96
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSVolitional and emotional movements can be affected unequally in central facial palsy. This dissociation has been explained by the existence of separate neural pathways for each, although little is known about such pathways. We conducted an MRI study of 39 patients with facial palsy to examine neuroanatomical dissociation between volitional and emotional movements. Three groups of patients were defined : “combination type”in whom both voluntary and emotional movements were affected, “volitional type”in whom only voluntary movements were affected, and “emotional type”in whom only emotional movements were affected. Three patients were classified as “ emotional type”and four were classified as“voluntary type”. The cerebral lesions in the “emotional type”were located nearer to the genu of the internal capsule and those of the “volitional type”were nearer to the posterior limb. These results suggest that there are separate neural pathways involving the genu and the posterior limb of the internal capsule, respectively.View full abstractDownload PDF (5468K) -
Naotaka MARUOKA, Hidekazu OTA, Miki KUSHIMA, Hideki NAITOH, Yoshiko TS ...2003 Volume 63 Issue 1 Pages 97-105
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIntraoperative rapid diagnosis of ovarian tumors is important to determine the appropriate surgical procedure. A retrospective study was conducted to determine the accuracy of intraoperative frozen sections. Intraoperative frozen section diagnoses were compared with the final histologic diagnosis. The benign (10), borderline (10), and malignant (10) cases by rapid diagnosis were analyzed for the DNA ploidy pattern using LSC. 146 ovarian tumor patients underwent intraoperative rapid diagnosis between May 1997 and December 2001. Among 82 ovarian epithelial neoplasms (surface epithelial and stromal tumors), 35 were benign, 15 were borderline and 32 were malignant. An analysis of DNA ploidy using LSC showed that two tumors out of 5 under diagnosed borderline tumors had an aneuploid pattern. Three cases had a diploid pattern. All 10 benign cases had a diploid pattern. 6/10 borderline tumors had an aneuploid pattern. Eight tumors out of 10 malignant tumors had an aneuploid pattern. In this study, in intra-operative rapid diagnosis of ovarian tumors, sensitivity of borderline ovarian tumors was elevated with DNA analysis by LSC. LSC will be one of the supportable methods for intraoperative diagnosis.View full abstractDownload PDF (8104K) -
Masafumi MARUYAMA, Souichirou TAKIGAWA, Katsunori INAGAKI, Kazuo FUKUS ...2003 Volume 63 Issue 1 Pages 106-110
Published: February 28, 2003
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThis is a report on a case of adhesions of tendons and nerves in the thumb and fingers due to circulatory failure as a result of a suicide attempt by taking a sleeping drug. We treated the patient by performing a decollement operation on the adhesions and early ergotherapy with CPM, which led to good results.View full abstractDownload PDF (5664K)
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