Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 56, Issue 1
Displaying 1-11 of 11 articles from this issue
  • [in Japanese]
    1996 Volume 56 Issue 1 Pages 1-31
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
  • [in Japanese]
    1996 Volume 56 Issue 1 Pages 32-45
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese]
    1996 Volume 56 Issue 1 Pages 46-50
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • Kenichi NAKANO
    1996 Volume 56 Issue 1 Pages 51-56
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Nasal cavity volume was studied in 11 patients with cleft lip and palate by magnetic resonance imaging. The areas of horizontal sections of the nasal cavity on the cleft and non-cleft sides were measured with the help of a personal computer and image analyzing software. Nasal cavity volume was determined by integrated volume calculation. The volume of each side was measured before and after cleft lip repair. Before cleft lip repair nasal cavity volume on the non-cleft side was larger than on the cleft side. However there was no significant difference in the volume of the cleft and non-cleft sides after cleft lip repair.
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  • Yoshiki MUTO, Kaori MURAKAMI, Tadakatsu SHIMAMURA
    1996 Volume 56 Issue 1 Pages 57-64
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We previously reported that the autoantibody to pancreatic α-amylase in the sera of nonobese diabetic (NOD) mice was detectable and that an increase of the antibody was usually followed by the onset of diabetes. The concentration of the autoantibody in diabetic mice was significantly higher than that in prediabetic mice. To investigate its possible clinical significance, α-amylase autoantibody was assayed in the sera of 28 patients (13 men and 15 women) with insulin-dependent diabetes mellitus (IDDM) and 218 healthy controls (27 men and 119 women) by the enzyme-linked immunosorbent assay. The average age of IDDM patients and age at onset of disease were 36±3 (mean±SE) and 25±2 years, respectively. The average age of healthy controls was 29±1 years. The concentration of the autoantibody in the IDDM group (7.66 equivalent to μg sheep anti-amylase IgG/ml) was significantly higher than that of the healthy control group (4.48 equivalent to μg sheep anti-amylase IgG/ml) . These findings suggest that a-amylase autoantibody may be associated with the autoimmune process of IDDM and might be used as a predictive marker for IDDM.
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  • Tetsuo SATOH
    1996 Volume 56 Issue 1 Pages 65-76
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Superselective angiography of the femoral medial circumflex artery was performed on 60 hips of 60 patients with intracapsular fracture of the femur to study the impairment of blood supply and subsequent revascularization process in the femoral head. Angiography was performed on 22 hips before osteosynthesis and on 56 hips, 2 or 3 months after surgery. There were 22 undisplaced fractures and 38 displaced fractures. Angiography before surgery showed interruption of the superior retinacular arteries (SRA) at the fracture region in 3 of 9 hips with undisplaced fractures and in 5 of 13 hips with displaced fractures. The SRAs were not visualized in the extraosseous area in 5 of 9 hips with undisplaced fractures and in 7 of 13 hips with displaced fractures. The normal pattern of the SRA was seen in the two remaining hips, one stage I case and one stage III case on Garden's classification. Angiography after surgery demonstrated normalized SRAs in 10 (50%) of 20 hips with undisplaced fracturess and in 2 (5.6%) of 36 hips with displaced fractures. Penetration of newly formed small vessels was seen in 8 (40%) undisplaced fractures and in 20 (56%) displaced fractures. The SRA was not seen in 2 (10%) undisplaced fractures and in 14 (39%) displaced fractures. Late segmental collapse was seen by X-ray in the follow-up period in 5 (36%) of 14 displaced hips that lacked SRAs on angiography. In conclusion, vascular impairment occurred not only in the fracture region but also in other extraosseous areas. Displaced fractures were more poorly revascularized than undisplaced fractures. Non-revascularization of the SRA was related with osteonecrosis of the femoral head.
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  • Shunsuke SATO
    1996 Volume 56 Issue 1 Pages 77-86
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We examined histologicaly joint tissue removed from 55 cases of revision total hip arthroplasty and compared these performed with in ceramic head-polyethylene socket joints (ceramic type) and metal head-polyethylene socket joints (metal type) . Newly formed capsules and membranous tissues were observed at the bone-cement or bone-component interface in all cases. The cases were divided into two group : early loosening and late loosening. In the early-loosening group, any tissue reaction was very mild and showed no necrosis in either type. Differences between metal and ceramic types were not observed. In the late-loosening group of metal type, large quantities of polyethylene-wear particles were observed in tissue. A strong tendency for degenerative necrosis with vascular dysformation was found. Extreme tissue reaction was most evident when there was a high number of polyethylene particles present. In the ceramic type, polyethylene particles in tissue were very rare, and when present were less than 10 μm in size. The necrotic area was limitcd focally. According to these findings, most special features for the clinical application of alumina ceramics in the ceramic ballpolyethylene socket combination, i.e., low abrasion and low friction, were demonstrated in the human body.
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  • Yasuhisa TOGO
    1996 Volume 56 Issue 1 Pages 87-97
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    This experimental study evaluated vascular impairment and revascularization in the femoral diaphysis caused by cavity reaming and insertion of a prosthesis. Forty-two rabbits (adult female Japanese white rabbits) were used for this study. Stainless steel wires were inserted into the femoral cavity of the rabbits after reaming. To compare the effects of the canal fill ratio, rabbits were divided into two groups according to the canal fill ratio : group A (n=21), the low canal fill ratio group and group B (n=24), the high canal fill ratio group. Vascular impairment and revascularization processes were examined by microangiography and histopathology. Studies were performed 1, 2, 4, 6, 8, 16, and 32 weeks after surgery. Findings were compared between groups A and B. Reaming and insertion of the wire impaired the nutrient artery. As a recovery reaction, newly formed vessels penetrated the ischemic areas around the wire. Gradually, these vessels penetrated further and formed a network around the wire at 8 weeks in group A and at 16 weeks in group B. Thus, a longer period was required to reestablish the canal blood supply in rabbits of the high canal fill ratio group than in the low canal fill ratio group. Histologically, reaming and insertion of the wire caused extensive avascular necrosis in the bone marrow and the cortex around the wire. Bone marrow repair was almost complete at 8 weeks. However, in the cortex, necrotic tissue persisted 32 weeks after the surgery in both groups. These results suggest a long period is required to revascularize and recover from bone necrosis after insertion of a prosthesis.
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  • Akira HARAGUCHI
    1996 Volume 56 Issue 1 Pages 98-104
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    In many cases of bilateral cleft lip and palate the gingivobuccal sulcus is absent. Numerous techniques for reconstruction of the buccal sulcus have been discussed. Reconstruction of the buccal sulcus with epithelization of the premaxillary donor site has been reported, however because of fusion and contraction, clinical results of the technique are unstable. The purpose of this study was to improve the clinical usefulness of this method. A new sulcus was produced via anterolateral maxillary incision in the rat. To avoid fusion of the buccal mucosa, it is important to pull up the upper portion of the new sulcus and immobilize an interposal material, such as silastic gel sheet or Terudermis (®) . Although spontaneous reepithelization of the maxillary defect occurs within 7 days, the new surface narrows owing to contraction before the tissue is mature The new epithelizated tissue requires or more 3 weeks to mature. To prevent relapse, it is important to apply the material for at least 3 weeks.
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  • Yuzo MOURI, Masao KOBORI, Hideru NEGISHI, Akiyoshi HOSOYAMADA
    1996 Volume 56 Issue 1 Pages 105-111
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Normovolemic hemodilution was studied with SALIN-HES in adult mongrel dogs anesthetized with halothane, nitrous oxide, and oxygen. Dogs were divided into two groups : a dopamine (DOA) group and a dobutamine (DOB) group. Hemodynamics and organ blood flow were studied with DOA and DOB at dosages of 5 and 10 μg/kg/min. Organ blood flow in renal cortex, renal medulla, and liver was measured with the hydrogen clearance method, and the percentage of cardiac output to each organ was calculated.
    As a result of normovolemic hemodilution, increases in the maximum rates of change of left ventricular pressure (LVdp/dt max) and cardiac index and a decrease in systemic vascular resistance were found in both groups. In the DOA group, LVdp/dt max was increased with both dosages. In the DOB group, heart rate and LVdp/dt max were increased. Blood flow in the renal medulla was significantly increased in the DOA group. In the DOB group, blood flow in the renal cortex and medulla were not changed ; however the percentage of cardiac output to the renal cortex was significantly decreased. Blood flow in the liver was not significantly increased in either the DOA or DOB group. These findings suggest that it is difficult to maintain renal and liver blood flow when either DOA or DOB is used.
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  • Kazuhiro NARITA, Kazuo SUZUKI, Ugen LEE, Sadatsugu AIDA, Yoshihiro FUK ...
    1996 Volume 56 Issue 1 Pages 112-115
    Published: February 28, 1996
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    A 68-year-old man was admitted for evaluation of upper abdominal pain. Gastrointestinal fiberscopy revealed multiple erosions in the body and antrum of the stomach. An acute gastric mucosal lesion was diagnosed. Famotidine, 20mg, was administered every 12 hours. The next day the patient experienced hallucinations and disorientation and loitered. The symptons persisted, and on day 4 famotidine was discontinued. His neurologic symptons relolved within 24 hours.
    Neurologic symptons due to H2-receptor antagonists are known, but few cases have been reported. The reported cases were either caused by large doses or were in elderly patients or patients with liver or renal failure. Our patient was an elderly man with normal liver and renal function. Famotidine is being used with increasing frequency, and its adverse effects are often neglected. We advocate careful usage since side effects, such as those seen in our patient, could happen.
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