Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 24, Issue 8
Displaying 1-4 of 4 articles from this issue
  • Kenzo Ishida
    1964 Volume 24 Issue 8 Pages 307-324
    Published: November 28, 1964
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The author collected f ourty three specimens of the stomach in the younger age from necropsy which died by other diesease than of the stomach. He investigated the frequencies of the following histological features in the mucous membrane as a) fibrosis, b) round cell infiltration, c) lymphatic fallicles d) intestinal epithelial metaplasia and e) erosive depression to compaire them with age. He has found that the features as a), d) and e) increase steadly with age, b) increases till five five years of age and thereafter becomes constant. The feature c) makes a special curve increasing to fifteen years of age and then decreases abruptly to 20 years without any flactuation in f urthor course. The frequency of those features differs markedly between the normal necropsied stomach and surgically resected stomach with chronic gastritis in the 3rd decade, but is nearly the same in 6th decade. Then it was concluded that the influence of the age must be highly estimated in the histological investigation of the stomach with chronic gastritis.
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  • Tsuyoshi Yamaguchi
    1964 Volume 24 Issue 8 Pages 325-334
    Published: November 28, 1964
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Development of drug resistance in Mutabile-type variant and its heredity to further variants mutated from Mutable-type variant were investigated to elucidate if there could be any relations between drug resistance and galactose sensitivity in the same strains of Bact. coli.
    Results obtained were as follows:
    1. Six strains of Mutabile-type variant were obtained by mutation from the old broth cultures of 2 hundred strains of Bact. coli isolated at the time of admission.
    2. From the variant MT (galactose resistant variant mutated from Mutabile-type variant) and RT (so-called back mutant of Mutabile-type variant to original) were obtained by mutation. Furthermore, M' (galactose sensitive variant, just the same one as the starting Mutabile-type variant) was obtained from the RT by mutation.
    3. In the so-called O (original) →M→RT (MT) →M' mutation process it was investigated how the pattern of the drug resistance to various antibiotics can be transmitted to the next generation of mutation.
    4. Drug resistance of Bact. coli against streptomycin, chloramphenicol, tetracyclin and sulphathiazol were well transmitted to Mutabile-type variant and to the offspring mutated from it, whether it was the one possessed at the admission or the one developed by conjugation with the multiple drug resistant Shigella.
    5. Drug resistance of Mutabile-type variant developed also by repeated exposure to antibiotics in serial passages in broth.
    6. Inheritance of drug resistance was also demonstrated in S-R mutation of Bact, coll.
    From the above experiments it seemed that development of drug (SM, CM, TC and SA) resistance in bact, coli and its inheritance were of no relation to Mutabile-type variation of the same organism.
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  • Tomoyoshi Yamashita, Yasutomo Nakajima, Eisuke Yabuki, Tetuji Tuchiyam ...
    1964 Volume 24 Issue 8 Pages 335-345
    Published: November 28, 1964
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Recently, as the progress of endocrinology, reported cases of adrenal cortical tumor are steadily increasing.
    Various opinions concerning the relationship between those tumors and endocrine activity are presented by many authors.
    Four autopsy cases of adrenal cortical carcinoma are reported.
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  • Tomoyoshi Yamashita, Yasutomo Nakajima, Takuya Kiyota, Tetuji Tuchiyam ...
    1964 Volume 24 Issue 8 Pages 346-349
    Published: November 28, 1964
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    An autopsy case of primary osteoid chondrosarcoma of the left lung in a woman of seventy-four years old, presumably arising from the bronchial mesodermal tissue, is reported.
    The primary osteoid chondrosarcoma of the lung is surprisingly rare.
    A search of the literature reveals a similar case reported by Greenspan in 1933 and there is no other reported case at the present time.
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