Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 68, Issue 6
Displaying 1-5 of 5 articles from this issue
  • [in Japanese], [in Japanese], [in Japanese], [in Japanese]
    2008 Volume 68 Issue 6 Pages 307-309
    Published: December 28, 2008
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • Hidefumi YAGI, Takemasa MIDORIKAWA, Kastumi MAKITA, Kunitoshi AITA, Ya ...
    2008 Volume 68 Issue 6 Pages 310-323
    Published: December 28, 2008
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Since August 2006 we have applied an in vitro chemosesitivity test using a collagen gel droplet embedded in a culture drug sensitivity test (CD-DST) to conduct individual chemosensitivity for each gastric and colorectal cancers. CD-DST was performed among 11 gastric cancer patients (19 samples) and 17 colorectal cancer patients (21 samples) in order to examine the characteristics of the patients and the results of the test. We exhibit the clinical course of4 patients with peritonitis carcinomatosa (2 with gastric cancer and 2 with colorectal cancer) . The evaluation of CD-DST succeeded at rates of 60.0% of the surgical specimens, 75% of ascites for gastric cancer cases: and 69.2% of the surgical specimens, 100% of ascites for colorectal cancer cases. The reasons for the failure of the CD-DST were lack of tumor cells in 3 cases of 4 surgical specimens, lack of tumor cells in one case, and poor proliferation of tumor cells in one of 2 samples of ascitic fluid in the gastric cancer cases. For the colorectal cancer cases, the reason for failure was contamination in all of 4 cases of surgical specimens. The sensitivity rates in 8 gastric cancer patients were 50.0% to 5-FU, 42.9% to CDDP, 57.1% to PTX, and 42.9% to SN-38: these in 12 colorectal cancer patients were 33.3% to 5-FU, 90.9% to L-OHP, 16.7% to SN-38, and 57.1% to PTX. Ac-cording to evaluation of treatments in 4 cases of peritonitis carcinomatosa with gastric and colorectal cancer, the changes of chemosensitivity to the drugs was recognized in comparison with its first sensitivity. The results suggest that repeated CD-DST using ascites might be clinically effective. CD-DST might be useful for individual cancer chemotherapy.
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  • Akishi KOURIN, Hiroki YOSHIKUMI, Naotaka MARUOKA, Osamu OGAWA, Yusuke ...
    2008 Volume 68 Issue 6 Pages 324-333
    Published: December 28, 2008
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    To investigate the efficacy of transpapillary endoscopic pancreatic stenting (EPS) for various diseases caused by pancreatic duct rupture and to evaluate accidental events. Subjects were comprised of 10 patients (7 men, 3 women) who underwent EPS at Showa University Fujigaoka Hospital over a 6-year period, from January 2002 to May 2008. Mean subject age was 55.8 years. EPS was performed for pancreatic pseudocyst (n=6), pancreatic pleural effusion (n=2), pancreatic ascites (postoperative internal pancreatic fistula, n=1) and pancreatic duct damage (n=1) . (1) A stent was placed in the cyst in 3 of the 6 patients with pancreatic pseudocysts, and in the pancreatic duct proximal to the cyst for the other 3 patients. With regard to therapeutic results, the pseudocyst disappeared in 2 patients with the stent placed inside the cyst and in a patient with the stent placed in the pancreatic duct. However, pancreatic cysts did not disappear in the remaining patients, so a drainage tube was placed through other routes. (2) In the 2 patients with pancreatic pleural effusion, effusion disappeared using a stent in the pancreatic duct proximal to the pancreatic duct stenosis in one patient and in the pancreatic duct distal to pancreatic duct rupture in the other patient. (3) In the patient with pancreatic ascites, ascites disappeared after a stent was placed in the residual pancreatic duct. (4) In the patient with pancreatic duct damage, a stent was placed in the pancreatic duct distal to duct rupture preventing extrapancreatic flow of pancreatic juice. Regarding complications, post-EPS infection developed in 3 patients. EPS is safe and effective therapy for pancreatic duct disruption.
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  • Mizue SHIROMARU, Takehiko ITO, Mihoko SHIMODA, Tomoko NAKAMATSU, Masak ...
    2008 Volume 68 Issue 6 Pages 334-344
    Published: December 28, 2008
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    The purpose of present study is to demonstrate the structure of patients' coping before and after abdominal surgery including digestive system disease. The research subjects consist of 103 people (66 males and 37 females) among 113 patients who underwent surgeries at a hospital in Tokyo. The average age was 59.6 years (±12.7), The period of data collection was between July 1, 2003 and May 31, 2004. The investigators handed the survey sheets to the subjects at the time of hospital admission the survey sheets were and the subjects filled them out 2-3 days before and after the surgery; directly collected by the investigators. Fifty-eight coping strategy items for pre-surgery and post-surgery were analyzed. Overall use of coping was more frequent with more variety in the pre-surgery period than in the post-surgery period (p=.038) . The 58 coping items were classified into the 16 areas. As a result of multidimensional scaling mapping in reference to the cluster analysis (Ward method) based on similarities among the 16 areas of coping before and after surgery and their structure, the items were successfully categorized into four strategies: help-seeking behavior, positive preparation and behavior, relaxation of tension, and avoidance. Help-seeking behavior and positive preparation- behavior were called problem-focused coping, and relaxation of tension and avoidance were named as emotion-focused coping in relation to the coping theory of Lazarus and Folkman (1984) . Among the four strategies, positive preparation- behavior strategies were used mostly in the pre-operation period based on the psychological stress from anxiety toward the forthcoming surgery. Relaxation of tension strategy was utilized significantly more in the post-operational period (p<.001) . We suggest relaxation of tension and avoidance strategies can contribute to pain relief. The malignancy group used more coping strategies of “affective avoidance” (p=.002), and “growth expectation” (p=.002) in the preoperational period, and more “future planning” (p=.03) in the posttest period than the non-malignancy group. The results suggest the importance of the nurses' role in helping patients use appropriate coping strategies based on their needs before and after surgery.
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  • Yoshitaka KII, Masazumi MIZUMA, Nobuyuki KAWATE
    2008 Volume 68 Issue 6 Pages 345-349
    Published: December 28, 2008
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We report a method of evaluation of weaning of the ventilator for the entire day for ventilatordependent patients with high cervical spinal cord injury. Two hospitalized patients with high cervical spinal cord injury were evaluated using polysomnography. Both patients had already had the ventilator removed during the daytime. The patients were evaluated by three doctors and one engineer to determine whether the ventilator could be removed during the nighttime. The state of breath using a chest and abdomen sensor and the state of sleep using electroencephalggraphy were observed. The ventilator was removed after sleep was confirmed by electroencephalography and the state of breathing was observed. For the patient who developed sleep apnea during this evaluation, it was judged difficult to remove the ventilator during the night. For the patient who continued sleeping without apnea, it was judged possible to remove the ventilator for the entire day. These cases suggest that this evaluation method is useful for determining weaning of the ventlator.
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