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Volume 60 (2000)
- Issue 6 Pages 657-
- Issue 5 Pages 553-
- Issue 4 Pages 423-
- Issue 3 Pages 309-
- Issue 2 Pages 147-
- Issue 1 Pages 1-
Volume 60, Issue 3
Displaying 1-18 of 18 articles from this issue
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[in Japanese]2000 Volume 60 Issue 3 Pages 309-311
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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[in Japanese]2000 Volume 60 Issue 3 Pages 312-316
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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[in Japanese]2000 Volume 60 Issue 3 Pages 317-321
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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[in Japanese], [in Japanese], [in Japanese]2000 Volume 60 Issue 3 Pages 322-326
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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[in Japanese]2000 Volume 60 Issue 3 Pages 327-330
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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[in Japanese]2000 Volume 60 Issue 3 Pages 331-333
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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-WHY IS THE PROGNOSIS POOR?-Daisuke KATAOKA, Mitsutaka KADOKURA, Makoto NONAKA, Shigeru YAMAMOTO, ...2000 Volume 60 Issue 3 Pages 334-339
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSLung cancer of the right middle lobe (RM) is rare and the prognosis has not been definitively established. To make clear the clinical feature and the outcome of lung cancer of the RM, 224 patients with primary non-small cell lung cancer were studied. Eighty-one patients with lung cancer of the right upper lobe (RU), 11 of the RM, 38 of the right lower lobe (RL), 64 of the left upper lobe (LU), and 30 of the left lower lobe (LL) were surgically treated. The five-year survival rates of the RU was 53%, RM was 30%, RL was 46%, LU was 44%, and LL was 49%. Complete resection was performed in 75 patients of RU, 9 of RM, 37 of RL, 59 of LU, and 27 of LL. The complete resection rate was 93% in RU, 82% in RM, 97% in RL, 92% in LU, and 90% in LL. After complete resection, the survival rate of the patients of the RU was 58%, RM was 62%, RL was 48%, LU was 47%, and LL was 53%. The rate of the RM was superior to the patients of the other lobes. In conclusion, lung cancer of the RM showed a low complete resection rate and 5-year survival rate; however, when complete resection was performed, the prognosis was not poor. Early diagnosis and complete resection are needed for improving the prognosis of RM lung cancer.View full abstractDownload PDF (519K) -
Hiroyuki SETO, Harumi SUZAKI, Seiji SHIODA, Yukihiro HASEGAWA, Toshiya ...2000 Volume 60 Issue 3 Pages 340-346
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSVarious inflammatory cells are known to infiltrate the nasal polyps in association with chronic sinusitis. In recent cases of nasal polyps encountered in Japan, eosinophils have been visualized using representative cellular infiltrates. Eotaxin is a C-C chemokine that acts to selectively induce local accumulation of eosinophils and basophils. Eotaxin is also believed to be involved in the infiltration of eosinophils in nasal polyps of patients with chronic sinusitis. However, only a few studies on eotaxin in nasal polyps have been performed. In this study, we investigated the localization of eotaxin in human nasal polyps and the identification of eotaxin positive cells using immunohistochemistry. The distribution of eotaxin immunoreactivity in the nasal polyps of patients with chronic sinusitis was found to correspond closely with the presence of eosinophils. Eotaxin immunoreactivity was also detected in some vascular endothelial cells. These findings suggest that eotaxin is produced by eosinophils and vascular endothelial cells in nasal polyps and is related to the accumulation of eosinophils in the nasal polyps.View full abstractDownload PDF (4201K) -
Keiko OGAWA2000 Volume 60 Issue 3 Pages 347-354
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe objective of this study was to clarify the actual condition of occupational therapy in the developing field of community-based rehabilitation by investigating through a questionnaire on what kinds of problems the occupational therapists engaging in communitybased rehabilitation have, and how they are coping with such problems. As a whole, “Do not use the term, patient, as a rule”was found to have been widespread, and “Doctors are taking little part in community based rehabilitation”was also recognized by community occupational therapists. In addition, “Community occupational therapy is not for treatments but services”, “Teamwork among multiple occupations is more difficult to obtain and maintain in a community than at a hospital”, “Assessment of both mental and physical functions cannot be sufficiently made, or enough information for the assessment is hardly available”, “The content of occupational therapy in communities is different from that at hospitals”, and“Instruments and fixtures required for training and duties are not sufficient”were also found as complaints of community occupational therapists. With increasing age and years of experience, community occupational therapists are exerting their ingenuity to establish good relations with multiple occupations. Quite a number of community occupational therapists were also found to be making efforts to inform the society of their existence and to promote a better general understanding of occupational therapy, to elevate themselves, and to establish the role of occupational therapy in community based rehabilitation. As for the nursing care insurance plan which will begin soon, community occupational therapists have vague uneasiness about predictable changes after its enforcement, and generations with longer experience appear to be taking the insurance more seriously.View full abstractDownload PDF (835K) -
Takayuki KATO, Toshio MOROHOSHI, Yukihiro HASEGAWA, Toshiya FUKUI, Mit ...2000 Volume 60 Issue 3 Pages 355-361
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSSeveral studies have found that the uptake of a radioisotope is reduced in the frontal or parietooccipital lobe on SPECT scans of patients with Parkinson's disease accompanied by cognitive impairment. The present study investigated the relationship between the results of SPECT imaging and those of cognitive function tests in patients with Parkinson's disease accompanied by cognitive impairment. Thirty patients with Parkinson's disease served as subjects, including 9 men and 21 women with an average of 66.1 years. Patients underwent 123-IMP SPECT and various cognitive function tests (Japanese alphabet pick-up test, Stroop test, Hasegawa's dementia screening scale, Raven color matrix, and course cube-combination test) . Next, three neurologists with no knowledge of the patient's clinical symptoms were asked to analyze the reduced uptake on SPECT scans as follows: frontal lobe, parietooccipital lobe, frontal and parietooccipital lobes, diffused reduction, and no reduced uptake. The results of SPECT imaging and each cognitive function test were compared. Reduced uptake in the frontal and parietooccipital lobes and diffused reduction correlated with decreases in cognitive function. Cognitive impairment is not notable when cortical blood flow is partially reduced, but is notable when cortical blood flow is widely reduced.View full abstractDownload PDF (599K) -
Takeshi OGAWA2000 Volume 60 Issue 3 Pages 362-370
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn this study 270 patients who had been treated for 10 years and had suspected rupture of the tendon and complete or partial thickness tears of the rotator cuff were diagnosed. Among these patients, MRI images in 50 cases were investigated to establish the diagnostic criteria for partial thickness tears of the rotator cuff. The rupture sites included the bursal surface in 15 shoulders, the articular surface in 30 shoulders, complicated cases of both surfaces in five shoulders with no intrasubstance. As for the imaging method, T2-weighted images were employed and the oblique coronary section, which is parallel to the scapula, was used as a imaging plane. From the results of the variation of the MRI signal intensity in the tendon, it was found that the signal intensity increased to 80% in the rupture of the bursal surface and 93.3% in the rupture of the articular surface. As for sites where the signals in the tendon increased, these were found at the bursal side in 83.3% of rupture at the bursal surface, and at the articular side in 100% of rupture at the articular surface. From these findings, the MRI-diagnostic criteria of partial thickness tears of the rotator cuff was defined as those cases which show a localized increase in signal intensity on the oblique coronary surface of T2 weighted images, but not in whole layers of the tendon. A high diagnostic rate with these criteria could be obtained with a sensitivity of 82.0%, specificity 90.9%, accuracy 84.7%, and positive predictive value 95.3%.View full abstractDownload PDF (5612K) -
Makoto YOSHIMURA2000 Volume 60 Issue 3 Pages 371-383
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMorphometry of the anterior cruciate ligament of 19 embalmed cadaveric knees was carried out. Insertions of the femoral side and the tibial side were investigated. An area on the photograph was measured using the ZEISS Company IBAS (Interaktives Bild-Analysen System) . The maximum width of the intercondylar notch was measured using slide calipers. The angle of torsion of the Anterior cruciate ligament was examined by investigating the fiber of the Anterior cruciate ligament from the insertion of the femoral side to the tibial side. Both the shape of insertion of the femoral side and the tibial side varied with each example. A fixed tendency was not recognized in the ratio with the width and the sagittal length of the midsubstance section and the insertion. The ratios of the sagittal length of the anterior cruciate ligament and the width varied. When the area on the femoral side became wide, the area on the tibial side became wide again, and the area of the ACL midsubstance became wide when the area of the femoral side insertion became wide as well. The angle of trusion of the anterior cruciate ligament was measured in the location to extend the geniculum completely the average was 84.5°.View full abstractDownload PDF (4250K) -
Norio SUZUKI, Masaaki NAGATSUKA, Hiroshi CHIBA, Hiroshi SAITO, Takumi ...2000 Volume 60 Issue 3 Pages 384-390
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSInsulin-like growth factor (IGF) is one of the important factors in the regulation of pubertal growth. Serum levels of IGF binding protein-3 (IGFBP-3), a major binding protein of IGF-I, and the proteolysis of IGFBP-3 modulate bioactivity of IGF-I. To investigate the effect of growth hormone (GH) on pubertal growth, IGF and IGFBP-3, immature female rats were hypophysectomized and GH was administered. Methods: Thirteen immature female rats (Wistar) at 28 days were hypophysectomized (Hx) . Recombinant hGH (0.4U/100g body weight) was administered daily for 2 weeks (Hx+GH group; n=5) . As contrasts, a sham operation was performed on 8 rats. Body weight was measured weekly and at 49 days, rats were sacrificed and blood samples were collected. Tibia length was measured. Serum IGF-I concentrations were measured by the RIA method and relative intensities of intact- and proteolysed IGFBP-3 expressions were measured by Western immunoblot (WIB) . Results: Body weight, tibia length and serum IGF-I levels were significantly decreased (p<0.05) by Hx. Administration of GH fully restored tibia length and IGF-I levels, while the body weight was not completely restored with the dose used. Relative intensity of intact IGFBP-3 in the Hx group was decreased significantly with augmentation of proteolysed IGFBP-3. In contrast, GH administration to Hx rats significantly increased intact IGFBP-3, and decreased proteolysed IGFBP-3. Conclusions: In the present study, the restoration of body growth, tibia length and serum IGF-I levels by GH administered to hypophysectomized immature female rats was demonstrated. Analysis of IGF-I, IGFBP-3, and proteolysed IGFBP-3 indicated that proteolysis of IGFBP-3, a potent modulator of IGF-I action, might be regulated by GH-IGF-I axis and plays an important role in pubertal development.View full abstractDownload PDF (1579K) -
Yoshisada SATO, [in Japanese], [in Japanese], [in Japanese], [in Japan ...2000 Volume 60 Issue 3 Pages 391-398
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThis study investigated the biomechanical stiffness of Anterior Lumbar Interbody Fusion (ALIF) with an interbody fusion cage. The objectives of this study were to clarify the changes of segmental stiffness after insertion of interbody cages anteriorly. The interbody fusion cage was packed experimentally with bone graft and inserted between the vertebral bodies through either an anterior or a posterior approach. Ten fresh frozen and thawed juvenile pig cadaveric lumbar L3-4, L4-5 osteoligamentous spines were used. The segmental stiffness and laxity after implantation of the interbody cages were studied and the direction of placement and the number of cages were compared.Mechanical properties were determined by testing lumbar verteral motion segments in flexion, extension, lateral bending and torsion. The five simulated conditions were, (A) an intact, (B) a single cage placed centrally and anteriorly, (C) a single cage placed laterally, (D) a single cage placed anterolaterally and, (E) two cages inserted anteriorly. There were significant effects of ALIF (surgery) on the configuration for each loading of flexion, extension, or lateral bending. The results indicate that under torsional stress, the stiffness of the (B) and (C) groups was less than that of the intact condition. The stiffness of the (D) and (E) groups was greater than that of the intact condition for all loading modes. A single cage placed anterolaterally had greater stiffness for all loading modes and had an effective configuration. Under stress of sagital and lateral bending and further torsion, the stiffness was greatest in the two cages inserted anteriorly.View full abstractDownload PDF (3038K) -
Toshihiro ANDOU, Osamu NAMIKI, Ethuo FUJIMAKI2000 Volume 60 Issue 3 Pages 399-406
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIt is commonly known that rheumatoid arthritis involves the elbow joint with joint destructive change. However, the natural history of the elbow joint and surgical indications based on this course is not well recognized yet. The goals of the present study were to document the natural history of the elbow joint in patients who have rheumatoid arthritis and to determine the stage at which the natural progression should be interrupted by surgical treatment. Methods : . We randomly reviewed the medical records and radiographs of the 296 (17.2%) elbow out of 1725 patients who have rheumatoid arthritis ; we could follow the natural history of 28 elbows of 22 patients in a long clinical term. Twenty-eight elbows could be categorized into one of three groups : Group A, No radiological progression at elbow joint (50.0%) ; Group B, Chronic and slowly development (over 6 years) of elbow joint destruction (17.9%) ; Group C, Acute or subacute development (Grade 0 to Grade 4, 5 in Larsen classification during 3-6 years) (32.1%) . Coronoid Height Ratio (CoHR) of the ulnar Coronoid process and Curvature Radius (R) of the ulnar sigmoid notch were measured radiologically. Results : There were no significant differences of the Coronoid Height Ratio in groups A and B. Acute or subacute progression of joint destruction was seen in the elbow that had a CoHR of over 60%. These findings were most frequent in group C. There was no relationship of Curvature Radius of the ulnar sigmoid notch between groups A, B and C. The Coronoid Height Ratio could be classified as stage I (<50%), II (50-59%), and ID (≥60%) . The results indicated that natural history of the rheumatoid elbow could be classified into stage I which could be recognized as almost normal, stage II which has a high risk of progression, and stage III which needs surgical treatment. Conclusions: Rheumatoid arthritis of the elbow joint commonly has the potential to progress rapidly, resulting in severe joint destruction. The Coronoid Height Ratio, one of the valuable parameters of the natural history, provides useful diagnostic information, particularly prognosis for progression of joint destruction. Through knowledge of the natural history is essential in the planning of appropriate and timely treatment to prevent progression of joint destruction and functional disturbance.View full abstractDownload PDF (3041K) -
Ayako FUJIMAKI, Taku TSUKAGOSHI, Fumio OHKUBO, Yoshiaki HOSAKA2000 Volume 60 Issue 3 Pages 407-412
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn 1997, we examined the DNA-synthesis stage cells of the cleft palate produced by Vitamin A. We have made a comparative study of 3 groups since then. Group VE: On days 7 and 8 of pregnancy, Vitamin E 12.5mg/100g weight was administered on days 9 to 11; Vitamin A 10, 000I.U./100g weight was done for 30 mother rats. Group VA: Vitamin A alone administered for 30 mother rats. Group C: 25 mother rats were the control. On the 21st day of pregnancy, the mother rats were sacrificed after the administration of BrdU to observe the 65 fetuses as samples of DNA-synthesis stage cells under a microscope. The incidence rate of cleft palate in this examination was 47.0% in the VE group, 73.5% in the VA group and 0% in the C group. The effect of Vitamin E on incidence control of the cleft palate produced by Vitamin A was 64.0%. Subsequently, the average of DNA-synthesis stage cell positive rate in the VE group was 16.0‰, 85.2‰ in the VA group and 7.7‰ in the C group. The effect of Vitamin E is anti-oxidant and is thought to restrain the incidence of cleft palate by preventing the production of the oxide of Vitamin A (=retinol acid) . In conclusion, we hypothesize that retinol acid disturbs the increase of cells although we could not determine the mechanism in this study.View full abstractDownload PDF (4280K) -
Toshihiro FUJIOKA, Shinichiro KAMEYAMA, Masahiko MURAKAMI, Hirohisa KA ...2000 Volume 60 Issue 3 Pages 413-418
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2000 Volume 60 Issue 3 Pages 419-421
Published: June 28, 2000
Released on J-STAGE: September 09, 2010
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