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Volume 51 (1991)
- Issue 6 Pages 601-
- Issue 5 Pages 487-
- Issue 4 Pages 369-
- Issue 3 Pages 249-
- Issue 2 Pages 131-
- Issue 1 Pages 1-
Volume 51, Issue 2
Displaying 1-16 of 16 articles from this issue
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Kazuo KATOH, Keiichiro YONEYAMA, Makoto ISHII1991 Volume 51 Issue 2 Pages 131-137
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTranscatheter arterial embolization (TAE) was performed for the treatment of hepatocellular carcinoma (HCC) in 26 patients with encapsulated HCC, defined by observations with angiography and the therapeutic effects were compared among subclassified types, truly-encapsulated and pseudo-encapsulated types. The tumor size was significantly larger in HCC with pseudo-encapsulated type than with the other type, and the reduction rate in tumor size after TAE was higher for HCC with truly-encapsulated type. However, there was no correlation between tumor size and reduction rate in the respective types. In only 3 of 12 patients with truly-encapsulated HCC, incompletely obstructed forms of tumor thrombosis were found in the 2nd branches of portal vein alone and all patients with pseudo-encapsulated HCC had complete or incomplete forms of tumor thrombosis in the 2nd branches of the portal vein. The reduction rate in tumor size after TAE was related only to the presence or absence of tumor thrombosis and to the complete or incomplete forms in the 2nd branches of the portal vein. We concluded that tumor size and tumor thrombosis in the portal vein should be examined to determine clinical indications for the treatment of HCC with TAE.View full abstractDownload PDF (722K) -
—SPECIAL REFERENCE TO MUSCLE COMPONENTS—Masaki MATSUDA, Junji ITO, Yoshikazu KOMURO1991 Volume 51 Issue 2 Pages 138-150
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMeasurements were made of the total cross-section of the abdominal area at the level of the 4th lumbar vertebral section by X-ray CT image. Cross sectional areas of subcutaneous fat, abdominal cavity (peritoneal and retroperitoneal spaces), vertebra and muscle were measured to assess their differences and correlation by sex, age and body type. Muscles were classified into rectus abdominis, transversus abdominis, obliquus internus abdominis, obliquus externus abdominis, quadratus lumbolum, psoas major, iliocostalis, long-issimus and spinotransversarius. Subjects were 78 healthy adults, 44 males and 34 females, at ages 30 to 70, averaging 52.3 years. The body types were classified into A, C and D by the Rohrer Index, and correlations were assessed by Pearson's product-moment correlation coefficient. The following results were obtained: 1) The actual measurements of subcutaneous fat, abdominal cavity, peritoneal cavity, retroperitoneal space and vertebrae increased with age. 2) There was significant correlation between total cross-sectional area and abdominal cavity (γ=0.81675), or subcutaneous fat (γ=0.84128) . 3) Muscular areas decreased with age in males, except transversus abdominis and spinotransversarius. In females, the muscles decreased with age except the lateral abdominal muscles. 4) There was correlation between total muscular cross-sectional area and each area of abdominis lateralis and iliocostalis in males ; and psoas major, quadratus lumborum and longissimus in females. 5) The propotion of abdominal cavity was largest in all body types in males, and the proportions of subcutaneous fat in A type and abdominal cavity in C and D types were largest in females. 6) In both sexes, the proportions of each muscle increased in the order of A, C and D type, but there was no correlation between Rohrer Index and muscles.View full abstractDownload PDF (2543K) -
Kanetoshi OOHARA1991 Volume 51 Issue 2 Pages 151-158
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMyofibrous organization in human hamstrings (m. biceps femoris caput longum ; BFL, caput breve ; BFB, m. semitendinosus ; ST and m. semimembranosus ; SM) were analyzed, and their functions were discussed. Materials were obtained from 17 humans (11 males and 6 females, average 61.4 years) . Sections, which were embedded in celloidin, were stained with hematoxyline and eosin. Results were summarized as follows. Muscle weight of m. biceps femoris was largest and occupied about 40% in hamstrings. SM and ST occupied about 35% and 20%, respectively. Cross-sectional areas in BFL and SM were more than two times as large as those of the other two muscles. The total number of muscle fibers in each muscle was about 200 thousand and the difference between muscles was small. The mean fiber size in the SM, was largest in hamstrings, and the BFL which belongs to the same muscle group had relatively large muscle fibers in human muscles. Fiber sizes in ST and BFB were smaller than those of SM and BFL and belonged to the small muscle fiber groups. The results suggest that SM and BFL are more developed in human hamstrings and have strong functions for knee flexion, and the ST and BFB act to assist or support the knee joint.View full abstractDownload PDF (882K) -
Masahide IWANAMI, Ken TAKEDA1991 Volume 51 Issue 2 Pages 159-166
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe examined the role of C-kinase and GTP binding protein in interferon-γ (IFN-γ) induced differentiation of human monocytic leukemia U-937 cells by using various agents that modulate both proteins. Differentiation of U-937 cells into cells with macrophage characteristics such as NBT reducing activity, Fc receptor activity, cell surface phenotype expression (CD11b, CD14), non-specific esterase activity and morphological maturation was induced by IFN-γ. The C-kinase inhibitor, H-7, did not inhibit IFN-γ-induced differentiation. The C-kinase activator, 1-oleoyl-2-acetylglycerol (OAG), did not induce differentiation of U-937 cells, but, in combination with IFN-γ, it did enhance differentiation. Thus, C-kinase may not be involved in the effectors stimulated by IFN-γ. As the number and dissociation constant of IFN-γ receptors on U-937 cells were not changed by treatment with OAG, OAG might enhance the IFN-γ-induced differentiation by modulating post-receptor events. Cholera toxin or pertussis toxin, which catalyse the transfer of ADP ribose to GTP binding proteins and lead to change of the protein functions, did not induce differentiation. However, when combined with IFN-7, cholera toxin remarkably enhanced, and pertussis toxin inhibited IFN-γ-induced differentiation. The results of intracellular cAMP concentration after treatment with IFN-γ, cholera toxin or pertussis toxin suggested that certain effectors other than adenylate cyclase might be involved in IFN-1-induced differentiation of U-937 cells.View full abstractDownload PDF (2450K) -
Seishi MATSUI, Takako UEDA1991 Volume 51 Issue 2 Pages 167-171
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe effects of brain irradiation (10 Gy) on the activity of superoxide dismutase (SOD) were examined in the cerebrum of male rats. The SOD activity was significantly decreased immediately after irradiation and returned to control level one hour later. The SOD activity was significantly decreased, two hours after irradiation, again and returned to control level three hours after irradiation. No siginificant change of the SOD activity was observed between the 1 st and 14 th days. These results indicate that 60Co γ ray irradiation affects SOD activity transiently within 3 hours after irradiation. When rats were treated with intraperitoneal injection of 10 mg bovine SOD one hour before irradiation, no significant decrease of SOD activity was detected. Exogenous SOD may prevent the decrease of endogenous SOD activity after irradiation.View full abstractDownload PDF (555K) -
Sadao NAKAYAMA, Akihiko YURA, Shunsuke IMASAKA, Hideyuki KURISHIMA, Ma ...1991 Volume 51 Issue 2 Pages 172-178
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe investigated changes of serum lipoproteins and pathological observations of the liver in rats with chronic liver injury induced by carbon tetrachloride (CCl4) . Male, Sprague-Dawley, 6 week old, 150-170g rats were used in the experiment. CCl4 was dissolved in olive oil, and 2 ml/kg body weight was given to each animal. Chronic liver injury was produced in rats by oral administration of 0.5 ml/kg CCl4 twice weekly for 10 weeks. Rats were sacrificed after 5 (5W-CCl4) and 10 (10W-CCl4) weeks of CCl4 administration, and the serum and livers were collected. In the 5W-CCl4 group, these was increase of high density lipoprotein subfractions (HDL1, HDL2, HDL3) and low density lipoprotein (LDL) . Increased HDL1 and LDL, and decreased very low density lipoprotein (VLDL) were also evident in the 10W-CCl4 group. The lipid content in HDL and LDL fractions were increased by CCl4 and the total protein (TP) content was decreased in the HDL. Decrease of lipid and TP content in VLDL, were also evident in the 10W-CCl4 group. Increases of total cholesterol and triglyceride, and decrease of phospholipid (PL) in the liver were observed in the 5W-CCl4 group. PL in the liver was also decreased by 10W-CCl4. Pathological examination of the livers revealed that CCl4 caused the formation of septum and pseudolobules by the proliferation of connective tissue. Lipid deposition in the pseudolobule of the liver was caused by 5W-CCl4. Loss of cytoplasm and nuclei, vacuolation and necrosis in the pseudolobular hepatocytes, but no lipid deposition were caused by 10W-CCl4. The results suggest that the increase of HDL and LDL by 5W-CCl4 was due to damage of lipoprotein metablolism in the liver associated with liver injury, and decrease of VLDL and increase of HDL1 and LDL by 10W-CCl4 were due to defective lipoprotein metabolism, and lipoprotein formation.View full abstractDownload PDF (3036K) -
Shuji MORIYA1991 Volume 51 Issue 2 Pages 179-185
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTo investigate the growth of nose and maxilla in cleft lip and palate, each angle between the nasal dorsal line, the auricular attaching line and the auricular long axis line was measured and analyzed. The subjects of the study were 3 month old infants and 69 cleft lip and palate, preoperative, 3 month old patients, and some 5-10 months old. The result were: 1) The order of the angle between the auricular attaching line and the nasal dorsal line was normal infant>unilateral cleft lip>unilateral cleft lip and palate>bilateral cleft lip and palate. Significant predominance was recognized in each other.2) The angle between the auricular attaching line and auricular long axis line decreased with increase in cleft width. Significant predominance was only between normal infants and bilateral cleft lip and palate. 3) The angle between the auricular long axis line and the nasal dorsal line had the same tendency, but there was no significant predominance between normal infants and unilateral cleft lip, nor between unilateral cleft lip and unilateral cleft lip and palate. Conclusion: In cleft lip and palate, maldevelopment of the maxilla was greater especially in cleft palate, and the auricular long axis line was not adequate for base line.View full abstractDownload PDF (678K) -
Koichi KOBAYASHI1991 Volume 51 Issue 2 Pages 186-196
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSMyofibrous organization was studied in human quadriceps femoris muscles (rectus femoris ; RF, vastus lateralis ; VL, vastus medialis ; VM, vastus intermedius ; VI) in 10 human subjects (5 males and 5 females, ages 44-86 years) . Muscle samples were embedded in celloidin and sections were stained with hematoxylin and eosin. The following results were obtained. 1) Muscle weights and cross-sectional areas were most predominant in VL, followed in order by VM, VI and RF. 2) Number of muscle fiber per sq mm was most predominant in RF (758), followed by VL (562), VM (474) and VI (461) . There was no difference between males and females. 3) VL had the most fibers in cross section, followed by VM, RF and VI. 4) Fiber sizes in VI, VM and VL were about 1300 μm2 and differences among those muscles were small. Fibers in RF (about 1000 μm2) were smaller than those in the other three muscles. Quadriceps femoris muscle had larger muscle fiber size than other human muscles. 5) Density of muscle fibers was highest in RF (71%), and in other muscles were about 60%. The results suggest that VL, which had the largest cross-sectional area and total fiber number, functions most predominantly for knee extention.View full abstractDownload PDF (920K) -
Koshi ICHIHASHI, Hiroshi HOSHINO, Hideki KOBAYASHI, Kenji MINOGUCHI, S ...1991 Volume 51 Issue 2 Pages 197-205
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTo investigate whether Ibudilast (3-isobutyryl-2-isopropyl pyrazolo [1, 5-a] pyridine), which is reported to be antagonistic to leukotriene (LT) C4, D4 and PAF, inhibits late bronchial response (LBR) in ovalbumin (OA) sensitized guinea pigs or not, the following studies were carried out. Twenty guinea pigs were actively sensitized by inhalation of OA at days 1 and 8. At day 15, OA challenge was performed under cover of 10 mg/kg mepyramine (i.p.), and the respiratory resistance (Rrs) was measured by the oscillation method for 96 hrs after the OA challenge. Immediate bronchial response (IBR) was observed within a few minutes and this was followed by 2 or 3 phase LBR that peaked at 6-8 hrs and 24 hrs after the OA challenge. The histamine concentration of bronchoalveolar lavage fluid (BALF) was significantly increased during the IBR after the antigen challenge (p<0.05) . Airway responsiveness to inhaled acetylcholine (ACh) was increased significantly 48 hrs after the OA challenge (p<0.01) . Pretreatment with Ibudilast inhibited the increased airway responsiveness to ACh at 48 hrs after the OA challenge (p<0.05) and increased histamine concentration of BALF during IBR (p<0.1) . The results suggest that Ibudilast inhibits airway hyperresponsiveness 48 hrs after OA challenge in OA sensitized guinea pigs.View full abstractDownload PDF (2760K) -
Thomas B. CHIANG1991 Volume 51 Issue 2 Pages 206-215
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSStastical analysis of the relations between blood group, cigarette smoking, and development of cleft lip and/or palate was undertaken. Primary cheiloplasty and/or primary pala-toplasty of 583 patients was followed up by the plastic and reconstructive surgical department of Showa University in the ten year period from 1979 to 1989. The result revealed that for male patients with cleft palate, the severity of the cleft defect was significantly associated with the blood group. It was also found that females with cleft lip and palate had significantly higher frequency of complete cleft defect if either one or both of the parents smoked cigarettes. There was no other significant association between the type and severity of the cleft defect, blood group and parental cigarette smoking.View full abstractDownload PDF (1320K) -
Hiroki TAKEDA, Makoto ARAI, Hiroyuki SUGIMOTO, Yuri HAYASHI, Hitoshi F ...1991 Volume 51 Issue 2 Pages 216-220
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA 39-year-old female was referred to our hospital for further evaluation of a severely tender lower abdominal fist-sized tumor. Laboratory data showed moderate anemia, leukocytosis and positive CRP. Morphological examination including ultrasonography, CT scan and radiography of the small and large intestines revealed that a 6×7 cm tumor compressed the small intestine. On laparotomy, the tumor was conglomerated with most of the small intestine and some of the sigmoid colon. Histological findings were compatible with desmoid tumor originating from the mesentery. Desmoid tumor of the mesentery has rarely been reported. Although surgical resection is considered to be preferable, recurrence after operation is not rare. Clinical analysis of long term follow up cases may clarify the clinical features of mesenteric desmoid tumor and suggest reasonable and appreciable treatment, including establishment of pre- and post-operative management.View full abstractDownload PDF (3719K) -
Masashi FURUKAWA, Yoshiaki HOSAKA, Kazuhisa HARAGUCHI, Masahiro HAYASH ...1991 Volume 51 Issue 2 Pages 221-225
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDermoid cyst of the helix is a rare disease, with 1 case having been reported in the world in the past 20 years. We experienced a case of dermoid cyst of the helix combined with cryptotia. An 8 month-old-girl was admitted to our hospital with the chief complaint of right ear deformity. During the operation for cryptotia, we chanced to find a tumor near the base of the helix and excised it. We then corrected the cryptotia deformity by the method that Hosaka had previonsly reported. Histopathology revealed tumor to be a dermoid cyst. Three years after the operation, the shape of the ear remained good and the dermoid cyst has not recurred. This was an interesting case of dermoid cyst that seemed to have caused cryptotia.View full abstractDownload PDF (5516K) -
Hiroko IWAI, Kimio NAMATAME, Tadaaki IKEDA, Mikio MAKUUCHI, Masahiko O ...1991 Volume 51 Issue 2 Pages 226-230
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSReports of gastrointestinal arteriovenous malformation are increasing as angiography develops. Among arteriovenous malformations, pancreatic arteriovenous malformation is rarely observed. We and our colleagues experienced two cases of gastric varices that were associated with arteriovenous malformation of the pancreatic head. In one case, gastric varices were observed in endoscopic examination and arteriovenous malformation of the pancreatic head was confirmed by angiographic examination. The patient had no history of liver cirrhosis and the varices were presumed to have developed from the occurrence of portal hypertension, caused by arteriovenous malformation. In another case, gastric varices were observed during close examination for hematemesis and sclerotherapy was conducted on gastric varices. The varices were presumed to be caused by A-P shunt due to arteriovenous malformation. Aggressive operative therapy on pancreatic arteriovenous malformation has been reported. However, in both of the present cases, no symptom attributable to arteriovenous malformation were observed, and a tendency to decrease wedge pressure of the hepatic vein was observed with embolization of the feeding artery. No later increase in varices was observed, and observation is continuing in outpatient clinic. We report these 2 cases including discussion and references.View full abstractDownload PDF (3748K) -
Susumu SHIMIZU, Yukio KATUMURA, Hidehiko OHTUKA, Hajime TAKAGI, Takano ...1991 Volume 51 Issue 2 Pages 231-235
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSA 59-year-old male was admitted with chief complaints of a slight fever and dry cough, and was hospitalized since an image of pneumonia was observed in his chest X-ray. No effect was obtained from administration of an antibiotic or antituberculous treatment, and organizing pneumonia was diagnosed by transbronchial lung biopsy (TBLB) . The symptoms were alleviated once by corticosteroid hormone treatment but recurred. A diagnosis of bronchiolitis obliterans organizing pneumonia (BOOP) was established by an open lung biopsy. An abnormally high value of CA19-9 was observed, though the symptoms were allayed again by corticosteroid hormone treatment, and pancreatic carcinoma was diagnosed by ERCP. Well differentiated adenocarcinoma was seen in the pancreas.View full abstractDownload PDF (5030K) -
Kenichi FUNO, Takuya UMEZAWA, Tomoki AIZAWA, Etsuko YOSHIDA, Toshiaki ...1991 Volume 51 Issue 2 Pages 236-241
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThree cases of rare of arterio-venous malformation (AVM) of the pancreas were reported with clinicopathological and pathomorphological studies. In case 1, the patient was a 48 year-old-man with marked portal hypertention, and AVM was present at the head of the pancreas, case 2 was a 61 year-old-man with AVM at the body, and case 3 was a 44 year-old-man with AVM at the tail. Histopathologically these AVM lesions were composed of various of blood vessels showing arterial, venous and intermediate structures. In case 2, arterial type blood vessels were more predominant, and in case 3, venous type were prominent.View full abstractDownload PDF (4650K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1991 Volume 51 Issue 2 Pages 242-247
Published: April 28, 1991
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (706K)
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