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Volume 68 (2008)
- Issue 6 Pages 307-
- Issue 5 Pages 269-
- Issue 4 Pages 207-
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- Issue 2 Pages 77-
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Volume 68, Issue 3
Displaying 1-9 of 9 articles from this issue
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[in Japanese], [in Japanese], [in Japanese], [in Japanese]2008 Volume 68 Issue 3 Pages 147-149
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (2867K) -
Masanori YOSHIE, Ryu MATSUOKA, Takashi OKAI, Akatsuki KOKAZE2008 Volume 68 Issue 3 Pages 150-154
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe purpose of this study is to evaluate fetal growth restriction (FGR) due to placental dysfunction by measuring oxygenation of the placenta using near-infrared spectroscopy. We selected 221 pregnant women with anterior placentation and a skin-to-placenta thickness of less than 3.5 cm; the subjects were divided into two groups, (1) normal fetal growth (195 patients, 222 cases) and (2) fetal growth restriction (26 patients, 45 cases) . Cases with fetal anomaly, multiple pregnancy and maternal complications were excluded. The measurement of tissue oxygenation index (TOT=oxyhemoglobin/total hemoglobin) was performed using the NIRO 300 model system (Hamamatsu Photonics KK), by attaching a probe to the maternal abdomen. We analyzed the relationship among TOT, placental weight, weeks of pregnancy and fetal weight. (1) TOT values were significantly higher in the FGR group than in the AGA group. TOT had a negative correlation regaiding fetal weight. (2) TOT showed a negative correlation for placenta weight, child birth weight/placental weight. Near-infrared spectroscopy could be used for measuring oxygenation status of the placenta and might help to evaluate placental function and severity of FGR due to placental dysfunction.View full abstractDownload PDF (519K) -
Hiroko ODAGAWA, Nahoko SHIRATO, Masaaki NAGATSUKA, Hiroshi CHIBA, Take ...2008 Volume 68 Issue 3 Pages 155-161
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe symptoms surrounding menstruation in young women have not been sufficiently clarified. To investigate the symptoms concerning menstruation in young women, we performed a quantitative analysis using modified MDQ (mMDQ) scores. Informed consent was obtained from 345 women, 15 to 20 years of age. The content of a questionnaire included background such as height, weight, lifestyle, menses history, and MDQ items regarding seven symptoms which are characteristic of PMS. The modified MDQ score was investigated before, during and after menses. Each item was given 0-3 points, and the total points of 54 items (M point) were applied for evaluation of symptoms surrounding menstruation. We used the Bonferron method for statistical analysis. There were no significant differences among ages. The means of the M point were 27.0 before menses, 36.2 during men-ses, and 9.7 after menses, respectively. The M point after menses showed no significant change with aging and was about 10 points, while the M point before menses increased with aging. We divided the subjects into three groups: 1) N (normal) group, M points before and after menses were under 10; 2) P group, M points showed over 10 points before menses and under 10 after menses; 3) Q group, M points before and after menses were over 10. The M point during menses of the P group (37.2) was significantly higher than that of the N group (14.3) . The percentage of the N group decreased with aging, while those of the P and Q groups increased. It was shown that the MDQ score with symptoms characteristic of PMS was useful for evaluating symptoms surrounding menstruation in young women, and the women with severe symptoms before menses increased in number with age and most likely experienced severe symptoms during menses.View full abstractDownload PDF (756K) -
Hikaru IZAWA, Hironobu UMEZAWA, Masaya FUJISHIRO, Yasuhiro ISHIWATA, T ...2008 Volume 68 Issue 3 Pages 162-174
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTo date, the absorption-elution test has been widely used for ABO blood grouping of bloodstains, hairs, nails, and teeth. Bloodstains found at a criminal scene are often diluted and hemolyzed with water. Few papers dealing with the accuracy of the absorption-elution test in such stains have been published. In this study, a semiquantitative analysis of the absorption-elution test was performed using bloodstains made by dropping whole blood and blood dilute with various solvents onto filter papers, cotton, silk, nylon, polyester, polyestercotton, linen, wool, and rayon. When blood samples obtained from 30 different (group A: 10, group B: 10, group AB: 10) adults were diluted with normal saline or distilled water and dropped onto filter papers, detection limits of group A antigen for the absorption-elution test were 8-fold or 16-fold dilution with either solvent; those of group B antigen, 16-fold or 32-fold. When the same blood (group A, B, AB: leach) was diluted with normal saline or distilled water and dropped onto various materials, detection limits of group A antigen for the test were 4-fold or 8-fold dilution with either solvent for all 9 materials; those of group B, 16-fold or 32-fold dilution. When the same blood (group A, B, AB: leach) was diluted with various solvents and dropped onto filter papers, detection limits of group A antigen for the test were 4-fold or 8-fold dilution with all 9 solvents; those of group B, 16-fold or 32-fold dilution. The use of papain-treated red cells instead of non-treated cells improved the detection limit of group A antigen for the absorption-elution test into 32-fold dilution with normal saline and improved the detection limit of group B antigen into 64-fold dilution. When bloodstains were stored for up to 6 months under indirect illumination at room temperature, the detection limits of group A antigen for the test decreased to 2-fold dilution with the saline 6 months after storage; those of group B antigen, to 4-fold dilution.View full abstractDownload PDF (3273K) -
Masaya FUJISHIRO, Hideaki SOBUE, Rikuro TAIRA, Takeyuki OHTAWA, Hirono ...2008 Volume 68 Issue 3 Pages 175-181
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSHumans and great apes do not possess urate oxidase (uricase) : hence, uric acid (UA) is the main end product of purine metabolism in these species. Based on the facts described above, a single determination of UA has been widely used for identification of human urinary stains. However, Dalmatians excrete a large amount of UA because the reuptake of UA in urinary tubuli is disturbed in dogs. Fecal stains of birds usually contain a large amount of UA since it is their final product of protein metabolism. Therefore, the single determination of UA is not reliable for identification of human urinary stains. To establish a more reliable method, creatinine (Cre) was chosen as an indicator of the concentration of urinary components. Simultaneous determinations of UA and Cre were carried out in experimentally prepared stains of human and animal urine; human body fluids along with feces of birds were performed using high performance liquid chromatography (HPLC) . The UA /Cre quotients in human urinary stains were 0.61-2.19 (mean±standard deviation, 1.06±0.32), whereas those in other mammals including Dalmatians were under 0.44, and those in fecal stains of birds were over 15. Stains of other human body fluids tested gave extremely small peaks of UA and Cre on HPLC chromatograms; the quotients were over 4.0. From the results obtained, it is reasonable to assume that human urinary stains give values of between 0.5 and 2.5 of the UA/Cre quotients, and that stains with such values are urinary stains of humans or great apes. The present method requires only a small amount of stains, approximately 5 by 5 mm, and conventional HPLC. Since this method is simple, reliable and inexpensive, it would seem to be useful for forensic science practice.View full abstractDownload PDF (746K) -
Michiari KAWAMO, Takumi ABE, Hitoshi IZUMIYAMA2008 Volume 68 Issue 3 Pages 182-191
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn patients with brain hemorrhage, the entire visualized pyramidal tract was established as an area of interest (ROT) . Its Fractional Anisotoropy (FA) value was determined by diffusion tensor analysis (DTA), and its relationship to motor function at the onset and three months later was investigated. In 30 patients with brain hemorrhage accompanying paralysis, MRI was performed during the subacute phase (6-14 days after onset) . In addition, using a workstation, DTA was performed in order to visualize the pyramidal tract. The FA of the ROT was measured on the affected and unaffected sides, and as previously reported, the ratio of FA in the affected and unaffected sides was calculated. Subsequently, we examined the relationship between the FA ratio and motor function prognosis. Motor function prognosis was assessed based on the sum of the Brunnstrom stage at the onset and three months later. A strong correlation coefficient existed between the FA ratio of the entire pyramidal tract and the sum of the Brunnstrom stage three months after onset (0.74, p<0.001), and prognosis of motor function tended to improve in patients with FA ratios of 0.95 or higher. Patients with mild paralysis were identified in order to ascertain the degree of improvement in paralysis, and a significant correlation between the FA ratio of the entire pyramidal tract and the degree of improvement in the Brunnstrom stage was observed (correlation coefficient 0.77, p<0.001) . When compared to putamen hemorrhage, the FA ratio affected the prognosis of paralysis more in thalamic hemorrhage. The results suggest that in patients with an FA ratio of 1.0, the recovery rate of paralysis three months after onset is markedly high. In brain hemorrhage patients, a reduction in the FA ratio of the entire pyramidal tract was correlated with the functional prognosis of motor paralysis, and in thalamic hemorrhage, it may be possible to predict motor function based on FA ratios. Hence, the DTA of the pyramidal tract in brain hemorrhage patients appears to be useful for predicting function.View full abstractDownload PDF (4843K) -
Masaomi FUKUZUMI, Takeo TEDORIYA, Masahiro OHNO, Masaya OI, Takahisa O ...2008 Volume 68 Issue 3 Pages 192-198
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn spite of non-thrombogenic coating, the patency of smalldiameter vascular prosthesises not determined the kinetic property of natural or synthetic vascular grafts is considered one of the most important factors for patency, but accurate measurement of this property is an elusive goal. In order to measure the vascular kinetic property in vivo, we developed a novel contact-type vascular shape sensor. The displacement of vascular shape is transmitted to slender probes and is sensed by eddy current sensors outside the body. Another feature of this sensor is the precise measurement in two dimensions using two pairs of probes and sensors. We simultaneously measured blood pressure and a cross section area of the porcine carotid artery in vivo using this device. In addition to the native artery, an interposed femoral vein graft and expanded polytetrafuluoroethylene (ePTFE) graft were assessed. When the pressure / sectional area ratio for the vessels was plotted, hysteresis loops reflecting viscoelasticity were observed. Elasticity was assessed by compliance, so distensibility was calculated from systolic / diastolic pressure and the sectional area gradient. Viscosity was estimated as the area within the hysteresis loop. Results showed distensibility to be 19.6×10-4 mmHg-1 in the artery, 8.9×10-4 mmHg-1 in the venous graft, and 2.2×10-4 mmHg-1 in the ePTFE graft. Areas within the loop were 0.114 mmHg for the artery, 0.037 mmHg for the venou graft, 0.062 mmHg for the ePTFE graft. Thus, the native artery showed not only higher compliance but also higher viscosity than the natural or synthetic vascular grafts. We succeeded in assessing vascular viscoelasiticity quantitatively using the sensor.View full abstractDownload PDF (3091K) -
Keiichi IEZUMI, Atsuko MASUNAGA, Toshiyuki MITSUYA, Mikio MASUDA, Syui ...2008 Volume 68 Issue 3 Pages 199-203
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe describe a rare pulmonary tumor of a 73-year-old Japanese man. The tumor was located in the left upper lobe and measured 35×25×25 mm. The histological diagnosis was lymphoepithelioma-like carcinoma (LELC) on routine HE-stained sections, whereas the tumor cells did not prove to possess the EBV genome using in situ hybridization for EBER-1. Although this case was not classified into the LELC category based on 2004 WHO classification, a few Caucasian cases reported from Western countries were all EBV-negative LELC before publication of the 2004 WHO classification. Our case must represent the same pattern of these Caucasian cases. Moreover, our case showed tumor-infiltrating lymphocytes possessed the EBV genome. There are no reports of tumor infiltrating lymphocytes of pulmonary LELC with the EBV genome. However, there are some reports of tumor-infiltrating lymphocytes possessing the EBV genome in pulmonary carcinoma of other histological typings. On the other hand, some reports have demonstrated EBV genomes in the tumor cells of pulmonary non-LELC. Therefore, we conclude that histological formation of pulmonary LELC does not require the EBV genome, although EBV might be related to tumorigenesis of some cases of pulmonary carcinoma.View full abstractDownload PDF (5827K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2008 Volume 68 Issue 3 Pages 204-206
Published: June 28, 2008
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (298K)
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