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Volume 15 (1955 - 195･･･
- Issue 6 Pages 369-
- Issue 5 Pages 333-
- Issue 4 Pages 247-
- Issue 3 Pages 181-
- Issue 2 Pages 99-
- Issue 1 Pages 1-
Volume 15, Issue 4
Displaying 1-9 of 9 articles from this issue
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Ryoji Uchimura, Susumu Nakazawa1955 Volume 15 Issue 4 Pages 247-252
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
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Shunji Ota, Kenichi Hirose, Tomosaburo Kono, Kiyoshi Aizawa, Hana Ishi ...1955 Volume 15 Issue 4 Pages 253-263
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe authors investigated the relationship between the absorption of histamine and the motility of colon. As the results, they learned that the combined application with histamine chloride of the drugs which promote the absorption of histamine in the large intestine excepting some of the aromatic carbonic acid preparations, accelerates the motility of colon induced by histamine application.View full abstractDownload PDF (16395K) -
Harunori Asakawa1955 Volume 15 Issue 4 Pages 264-266
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSSubjects: The subjects for this experiment were 3 cases of Degree I patients, 7 cases of Degree II and 3 cases of Degree III.
Method of Experiment: The subjects were requested to step up and down a platform of 30 cm high at a rate of 18 times per minute. The expired air was taken into the Douglas bags once before and even during the exertion and 3 times after the exertion. The samples of air were analysed by means of Haldane's apparatus. The pulse rates were also taken on those occasions. The rates of energy metabolism (ER) were determined by the following formula in order to omit personal factors.
ER=O2 intake during exertion-O2 intake in repose/O2 intake in basal metabolism
Results of Experiment: 1) The rates of energy metabolism (ER) in the mild cases may, in general, rapidly increase with the initiation of the exertion and decrease suddenly with the termination of the exertion. However, severe cases show low rates of energy metabolism during the exertion, but show high rates after the exertion on the contrary with delayed recovery. 2) The rate of fluctuation in the pulse rate may progress similarly to that of the rate of energy metabolism.View full abstractDownload PDF (391K) -
Harunori Asakawa1955 Volume 15 Issue 4 Pages 267-271
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESS1. In the present paper, by means of the respiration curves, the pattern of the respiratory function was investigated on 36 patients, which were diagnosed as pure silicosis.
2. The amplitude at rest and the maximal amplitude at exertion in the mild cases demonstrates roughly an equal value to that in the healthy subject, while they become larger in the severer cases.
3. The time required for the recovery after the termination of exertion is prolonged in the severe cases.
4. The fluctuations in the pulse rate and blood pressure generally coincides with those in the respiration curve.
5. When observed from the product of the average amplitude of the curve in each one minute and its respective pulse rate, the increase in the value due to exertion is smaller and the value at rest is recovered in relatively short period of time in the healthy persons and in the initial stage of silicosis. However, as the severity of silicosis progresses, the increase in the value becomes larger and the time required for the recovery of the normal value is prolonged.View full abstractDownload PDF (573K) -
Masao Yatagai1955 Volume 15 Issue 4 Pages 272-288
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe author investigated the sulfuric acid conjugation of vanillin, bromovanillin methylprotocatechualbarbituric acid and bromomethylprotocatechualbarbituric acid, in rabbit, and further investigated the influence of the hypnotica (barbital and phenobarbital) on the sulfuric acid conjugation. He also investigated the behavior of barbital and phenobarbital on the glucuronic acid conjugation of bromovanillic acid. From the histological findings of liver of the rabbit treated with the above various substances, the author attempted to learn the extent of the toxicity of vanillin and its derivatives. The followings are the results of the investigation.
Vanillin, bromovanillin and their barbituric acid derivatives conjugate sulfuric acid or glucuronic acid without demonstrating any general symptoms inn the rabbits. However, a minor part of the above substances are excreted as vanillic acid after oxidation. On the other hand, the histological damage in the liver of the rabbits progresses in a relatively mild manner.View full abstractDownload PDF (5285K) -
Tomotaka Katada1955 Volume 15 Issue 4 Pages 289-309
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn the present paper, the author investigated the influence of various splenic components of various animals on the agglutinin production in the rabbits. Further, the author conducted similar experiments with aromatic aldehydes, furan aldehydes, and a few aminoacids, which possess inhibitory action against the damages in the liver, thereby attempted to elucidate the significance of the combined administration of the splenic components and various substances described in the above, which had been conducted by various workers.
As the results of the above experiments, the presence of the agglutinin production promoting substances in the spleen of various animals, especially of cattle and hog, was confirmed, though the isolation of the fraction exercising a particularly strong action was unsuccessful. Nevertheless, it was learnt that, combined administration of alcohol-soluble and -insoluble fractions of cattle spleen and the leucine-like substance isolated from the same spleen most remarkably promotes the active immunization. Furthermore, in view of the fact that dl-leucine, 1-tyrosine, salicylaldehyde, benzaldehyde, vanillin, acetyl-oxymethylfurfural possess the active immunization promoting action, the administration of splenic components combined with these substances was considered to have a specific significance to the living subjects.View full abstractDownload PDF (2352K) -
Shoich Nishinoiri1955 Volume 15 Issue 4 Pages 310-315
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn an attempt to observe, from the view point of the functions of reticuroendothelial system, the influence of the environment of the daily life and the conducts of life execrised on the disease resisting functions, the author investigated the fuluctuation in the carbon particle phagocytosis of neutrophile leucocytes before and after the routine works by the general industrial labourers as well as the experimental muscular exertions of approximately 7.5 in terms of R.M.R. for 30 minutes.
The followings are the outline of the results thus obtained.
1. when observed during a week, the degree as well as the rate of phagocytosis reached the maximum in the middle of a week, and showed a gradualy diminishing trend toward the end of a week. In the daily observation, they showed a gradual rise from 8 a.m. and reached the maximum at 4 p.m., demonstrating a gradually diminishing trend until 8 p.m.
2. In the case of a light work not exceeding 20 in terms of R.M.R., no change in the phagocytosis was recognized if the work-amount was less than 400, while a remarkable diminution was demonstrated when the amount of work exceeded 500. Therefore, the disease resisting function observed from the above phase was considered to have been suppressed.
3. In the case of a precision work, which is liable to induce a distinct lowering in the level of cerebral excitement, the disease resisting function seemed to be much more distinctly affected compared with the case of muscular work when observed from the view point of phagocytosis of leucocytes even if the intensity and the amount of work was small.
4. In the case when the intensity of work was approximately 7.5 in terms of R.M.R., the phagocytosis of leucocytes was found affected even when the workamount was less than 400.
5. As to the comparison of the phagocytosis of leucocytes in the corpulent and slender subjects, it seemed that corpulent subjects, who are burdened with more exertion, are more seriously affected than slender subjects are affected even if they are undertook an equall degree of work.View full abstractDownload PDF (739K) -
Takeshi Iwasawa1955 Volume 15 Issue 4 Pages 316-330
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSIn the present work, nutritionally well taken care of rats were fed with food containing sodium fluoride. In some cases, CaCO3, Vitamin D, Methionin etc. were further added. On these occasions, the morphological changes occurred in the oral glands, especially in the lingual glands and its relation to the growth and body weight were investigated. In the serous glands, among the oral glands (Ebner's gland), vacuolar degeneration, dissociation, fusion and atrophy of glandular epithelium were noted, but the atrophy and degeneration found in the efferent duct were mild. In view of the above findings, in the present experiment the regressive changes in the lingual glands were found generally more distinct in Ebner's glands than in Weber's glands (mutinous glands) . However, in the cases of the addition of CaCO3 alone, the influence could not be regarded consistent, though, when the histological findings were qualitatively studied, slightly more cases highly affected were found among those in the group without CaCO3, and higher loss in the body weight was noted in the group without CaCO3. From the above observations, the author presumed that the combination with CaCO3 acts against the harmful action of sodium fluoride as neutralizer and buffer.
In the cases of the addition of Methionin combined with CaCO3, the changes in the epithelium of the Ebner's gland were found extremely mild up to 7 ppm of NaF, but the changes suddenly became severe at the concentration of 10 ppm of NaF. The above fact is suggesting that the harmful action of NaF is inhibited by the combination with the threshold at 7 ppm.
Furthermore, the increased appearance of mast cells at the focus of fusing changes in the Ebner's glands suggests a correlationship to the formation of the secretion which possesses fusing action, thus makes the author to consider that it has a significant relation to the regressive changes, especially the fusing changes due to the toxic action of fluorine.View full abstractDownload PDF (4856K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1955 Volume 15 Issue 4 Pages 331-332
Published: September 30, 1955
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (280K)
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