巻号一覧
18 巻, 1 号
選択された号の論文の71件中51～71を表示しています
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大平 睦郎, 大宮 朗, 広瀬 政雄, 伊勢 泰原稿種別: 本文
1982 年 18 巻 1 号 p. 118-120
発行日: 1982/02/20
公開日: 2017/01/01
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原稿種別: 付録等
1982 年 18 巻 1 号 p. 121-
発行日: 1982/02/20
公開日: 2017/01/01
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武 豪, 木村 厚, 西田 茂, 平野 裕, 石原 通臣, 宗像 敬明, 東 義治, 富永 幹洋, 岡部 郁夫, 森田 建原稿種別: 本文
1982 年 18 巻 1 号 p. 123-127
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーIn the past 35 years, we have experienced 355 cases of HTPS, and about half of them, GER was found simultaneously by upper G.I. series. In the present study, in order to clarify the interrelationship between HTPS and GER, measurements of LESP including its gastrin response were done by open tip method. Control patients were consisted of 10 infants who had neither HTPS nor GER. THE following results were obtained. 1) GER(+) group; 6 cases were studied. The free and gastrin responces of LESP were lower than the control. But they increased markedly after pyloromyotomy. 2) GER(-) group; 10 cases were studied. There was no difference in free LESP, but the response to gastrin was lower than the control. However, it become to normal range after the opration.抄録全体を表示PDF形式でダウンロード (570K) -
森川 康英, 遠藤 昌夫, 横山 穣太郎, 鎌形 正一郎, 中野 美和子, 勝俣 慶三原稿種別: 本文
1982 年 18 巻 1 号 p. 129-133
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーEsophageal dysfunction has been reported after successful repair of esophageal atresia. Recent work has been focused on the function of the lower esophageal sphincter in view of gastroesophageal reflux (GER). This work was initiated to assess the long term result of esophageal surgery in children with special reference to the function of the lower esophagus. 25 children including 12 after esophageal atresia repair and 8 after successful surgery for esophageal stenosis were evaluated by upper GI sereise, measurement of mean lower esophageal sphincter pressure (LESP) in combination with pH measurement and endoscopy. 11 children who did not receive surgical treatment for esophagus were also evaluated. LESP less than 10cmH_2O was noted in 4 out of 5 GER cases. pH measurement demonstrated positive acid reflux in 5 and esophagitis of various degree was detected in all of them. Tetragastrin gave 27.4±18. 3cmH_2O of contraction to LES in these GER cases as well as non-GER cases. The response to atropine sulfate was significantly weak in GER cases, which was 3.4cmH_2O of decrease of LESP, although others showed marked relaxation of LES (13.4±5.9cmH_2O). Esophageal motility was tested by blowing up balloon in the esophagus at various position. Stimulus to the upper esophagus failed to initiate the relaxation of LES though mid-or lower esophageal stimulation resulted in the rise of intraesophageal pressure below stimmulating site and definite fall of LESP. Most GER cases (4/5) had end-to-end anastomosis for over 2.5cm of distance. As a result of this study, any single method was found to be insufficient in evaluating GER. The combination of manometry, pH study, GI sereise and endoscopy made the evaluation of GER more accurate and reliable. It should be stressed that a care has to be taken for end-to-end repair for "long gap" at the risk of GER.抄録全体を表示PDF形式でダウンロード (477K) -
高田 佳輝, Geraldine Kent, Robert M. Filler原稿種別: 本文
1982 年 18 巻 1 号 p. 135-139
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーCircular myotomy is useful method for bridging the gap in the case of esophageal atresia with wide gap. But its indication is still unclear because the maximal permissable tention for safe anastomosis and precise effects of circular myotomy on length and tention at anastomosis are not known. This study was undertaken to answer these questions. In 18 piglets that thoracic esophagus was excised from Ocm to 6.5cm, approximtion force between both ends was measured by dynamometer prior to anastomosis. When the approximation force was greater than 75 grams, anastomotic leak and marked scar formation was likely to occur at anastomosis. In piglets and neonate cadavers study, the upper third of esophagus was stretched by application of the traction force of 0-150 grams. At each traction force, the length of upper esophagus was measured before and after circular myotomy. Circular myotomy increased esophageal length by about 5mm for any traction force. To know the actual approximation force at the time of esophageal atresia repair is very helpful to make a decision for circular myotomy. If greater than 75 grams of force is necessary to approximate each ends, circular myotomy is indicated.抄録全体を表示PDF形式でダウンロード (414K) -
内藤 春彦, 佐々木 文章, 秦 温信, 内野 純一, 葛西 洋一原稿種別: 本文
1982 年 18 巻 1 号 p. 141-146
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーThe synchronizing effect of the combination chemotherapy of vincristine (VCR) and cyclop-hosphamide (CPM) on C-1300 murine neuroblastoma was investigated in vivo. A synchronizing effect of intraperitoneally administered (i.p.) VCR was observed by flowcytometry using Fried's formula for analysis and autoradiography. VCR (0.1 mg/kg) i.p. induced a G_2+M phase accumulation after 6 hours and an S-phase accumulation 9 to 18 hours later. The combined treatment with VCR (0.1 mg/kg) followed by CPM (100 mg/kg) after 12 hours weekly caused remarkable inhibition of the tumor growth during 4 weeks. The improvement of the animal survival rates were not to good as the tumor growth inhibitory effect. This may be because of the timing of injection of CPM, which may induce an S-phase accumulation of normal bone marrow cells and increased animal toxicity. To use a synchroniation method in vivo, it is important to know the cell cycles of both tumor and normal cells.抄録全体を表示PDF形式でダウンロード (431K) -
坂崎 由紀夫, 角岡 秀彦, 山川 洋右, 加藤 浩, 舟曳 純一, 長縄 伸幸, 加藤 敬純, 正岡 昭, 加藤 泰治原稿種別: 本文
1982 年 18 巻 1 号 p. 147-153
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーInvestigation of maturation provocative therapy in murine neuroblastomas was performed with dibutyryl cAMP, prostaglandin E_1 and papaverine or BL 191, but the results were not so satisfactory for the clinical application. It was lately found, however, that a protein factor obtained from the culture medium of glioblasts was rather promising effect for this kind of the therapy in Neuro2a, NS-20Y and NIE-115. This was different from the glial factor of Monard et al [Proc. Nat. Acad. Sci. 70: 1894, 1973] and was named glia-derived growth inhibitory factor (GDGIF), because of its inhibitory activity on cell division besides promoting morphological differentiation and inhibiting DNA synthesis in vitro. The factor, though only partially purified yet, had an apparent molecular weight of 100,000 and an isoelectric point of 5.0-7.5, and the activities were susceptible to protease digestion and inactivated by heat. The factor did not elevate the intracellular levels of cAMP and cGMP, and did not show any effect on glial cell lines, suggesting that its actions are highly specific to neuronal cells via cAMP-independent system. A significant prolongation of survival time was also noted in the neuroblastoma bearing A/J mice when the tumor cells were treated with the factor either before or after the inoculation.抄録全体を表示PDF形式でダウンロード (1929K) -
中平 公士, 竹内 敏, 塩川 智司, 玉手 信治, 山田 忠治, 梅田 耕作, 門脇 宏原稿種別: 本文
1982 年 18 巻 1 号 p. 155-159
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーMagnetometries of costal and abdominal wall movements during REM and NON-REM sleep were made in sixty normal children under two years of age to study the compensatoy costal respiration. It was confirmed that in the newborn infants their respirations are entirely abdominal in type and adult-type respiratory movements of rib cage and abdominal wall first develop at about four to five months of age. These physiological evidences imply that the newborn infant with unilateral phrenic nerve paralysis may need a respirator support for four to five months. However, such a long-term respirator care carries a considerable potential risk. The authors recommed a early operative plication of the paralytic diaphragm when nerve paralysis did not recover after a few weeks of respirator care.抄録全体を表示PDF形式でダウンロード (518K) -
草島 勝之, 伊黒 隆, 稲岡 正己, 浅井 康文, 長谷川 正, 小松 作蔵原稿種別: 本文
1982 年 18 巻 1 号 p. 161-164
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーDuring 22 years from 1959 to 1981, 422 sternal turnover operation for funnel chest have been experienced. A couple of technical modification have been developed. 1. High transsection of sternum is done, preferably at first or second intercostal space. 2. When either side of rib is transsected, attempt is made to leave posterior portion of periostium in the anterior mediastinum. Turned over sternum is placed on this remaining perostium, which is expected to promote bone union. 3. The sternum is turned over at 180 degree with rectus abdominal muscle attached to xyphoid process, which is expected to maintain blood supply.-Pedicle sternal turnover-this technique can be done without affecting the merit of standard sternal turnover operation. At least there is no demerit in employing this technique. 4. From cosmetic stand point, transverse skin incision is made for those of which deformity configuration is localized mainly in central and lower portion of sternum.抄録全体を表示PDF形式でダウンロード (718K) -
花松 正寛, 望月 泉, 大井 龍司, 葛西 森夫原稿種別: 本文
1982 年 18 巻 1 号 p. 165-168
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーIn 26 corrected cases with biliary atresia, we examined and compared a histology of the liver specmen taken at the time of radical operation and closure of the jejunal stoma. The following findings were seen in the second biopsy specimen: 1. In most of the cases, fibrosis of the liver progressed. 2. Proliferated bile ducts in the portal area reduced in number. It is of interest that on bile ducts can be seen in portal area in 8 cases. 3. Persistent round cell infiltration was noted in about a half of cases. 4. Bile stasis, characteristic giant cells and foci of extramedullar hematopoiesis in the liver were completely disappeared, 5. Liver cell cords and limiting plates showed marked improvement from previous disarrangement.抄録全体を表示PDF形式でダウンロード (441K) -
安藤 久実, 伊藤 喬廣, 杉藤 徹志, 長屋 昌宏, 弥政 洋太郎原稿種別: 本文
1982 年 18 巻 1 号 p. 169-174
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーOperative cholangiography were perfomed in six patients and PTC in eleven patients. These patients were classified into two groups according to the radiological findings. Group I: The intrahepatic bile duct was filled with Urographin. Cholangiogram demonstrated that the lumen of these intrahepatic bile ducts were irregular and obstructed partially. Eight patients consisted the group I. Group II: The intrahepatic bile duct was recognized with negative shadow by cholangiography. Nine patients were included in this group. It seems that lymph vessels were vissuarized. Communication between the intrahepatic bile duct and lymph vessels was demonstrated in a patient.抄録全体を表示PDF形式でダウンロード (1415K) -
長屋 昌宏, 伊藤 喬広, 山田 昂, 渡辺 芳夫, 弥政 洋太郎原稿種別: 本文
1982 年 18 巻 1 号 p. 175-184
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーEsophageal manometric studies, 24-hrs esophageal pH monitoring, and measurement of serum gastrin concentration were carried out in fourteen cases with congenital hypertrophic pyloric stenosis to investigate the esophago-cardiac function before and after operation. The results were as follows: 1. Manometric studies; The tone of high pressure zone (HPZ) at the distal esophagus before operation was significantly lower than that after operation, (78±52.5 versus 111±38.0 mmH_2O. p<0.01). There was no difference in the length of HPZ before and after operation. The end expiratory pressure in the esophagus before operation was higher than that in the stomach, whereas after operation, the esophageal pressure was lower than the gastric pressure. 2. 24-hrs pH monitoring of the distal esophagus; The percent time of pH<4 for the total period (24 hrs) before operation was 12.5±4.74% and that after operation was 0.95±0.96%. The difference was statistically significant. The number of reflux episodes before operation was significantly more than that after operation. (123±60 times versus 18±18, p<0.05). 3. The serum gastrin concentration; The mean of serum gastrin concentration before operation was 60.4±23.6 pg/ml, whereas after operation, that was 122.4±60.4 pg/ml. the difference was statistically significant (p<0.05). But, there was no statistical correlation between the tone of HPZ and the serum gastrin concentration. These results indicate that the esophago-cardiac function of congenital hypertrophic pyloric stenosis before operation is impaired.抄録全体を表示PDF形式でダウンロード (718K) -
大川 治夫, 澤口 重徳, 山崎 洋次, 坂庭 操, 石川 詔雄原稿種別: 本文
1982 年 18 巻 1 号 p. 185-191
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーUsing the canine models, the mode of activation of the pancreatic enzymes contained in the pancreatic juice was studied. Firstly, by an experiment of simple mixture of 1 ml of the fresh pancreatic juice and 15ml of the bile, it was observed that trypsin and elastase activities were completely negative after 3 hours' storage in the gallbladder and after 24 hours' incubation in 37℃in vitro, while the amylase value was preserved constantly around or over 10,000 IU/l. In the models of pancreatico-choledochostomy without enterokinase in the bile, the activation of trypsin and elastase was observed in all of 8 adult and 4 puppies except in one adult dog. The daily and hourly measurements of enzymic activity in the representative models revealed a constantly high level in amylase and simaltaneous activation of trypsin and elastase. The etiology of the disorders of hepatic and biliary systems in this anomaly was discussed in relation to the activation of the refluxed pancreatic enzymes into the biliary tract.抄録全体を表示PDF形式でダウンロード (566K) -
片山 修, 馬淵 原吾, 倉光 秀麿, 織畑 秀夫原稿種別: 本文
1982 年 18 巻 1 号 p. 193-203
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーIn literature, twenty three patients of fetus-in-fetu were collected and reviewed in Japan. Most patients were found in the neonatal period or in early infancy, but two were stillborn babies. Sixteen patients were male and seven female. Most fetus were found in the retroperitoneal space of the host, but Kakizoe reported a case with the fetus located in the scrotal sac and Shimada a case in the cranium. The capsule (amnion) and the cord (umbilical cord) were identified in many cases but the chorion and the placenta were not observed. The skin, hair, brain, bone, cartilage, muscle and intestine were found in many fetus. The sex of the fetus was almost always same as that of the host. All fetus had several defects such as anencephalia, polydactylia, oligodactylia, syndactylia or loss of extremities. All patients under-gone operation did well. In conclusion, a fetus-in fetu is a monster included in a normal fetus.抄録全体を表示PDF形式でダウンロード (963K) -
島田 憲次, 森 義則, 生駒 文彦原稿種別: 本文
1982 年 18 巻 1 号 p. 205-215
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーIn the past 8 years, 20 children with congenital urethral valve have been managed. All valvular structures were endoscopically confirmed as Young's type I. Clinical findings included retention, UTI with fever, failure to thrive, urge incontinence, enuresis, and in rare cases, palpable kidneys and urine ascites. Five neonates showed the lower abdonimal mass. As the associated anomalies, hypospadias was seen in 7 children. By the urographic examinations, vecico-ureteral reflux was seen in seven and prevesical ureteral atenosis in seven. In these who showed a marked dilatation and/or a prolongation of the posterior urethra with prominent bladder neck on MCU, grossly dilated upper urinary tracts due to reflux or stenosis were observed. By the cystometric examination, hypertonic intravesical pressure was observed in four of eight boys. An uninhibited contracture was seen in four children. The renal function was impaired in five boys with severe dilatation of the bilateral upper tracts. As the treatment the valve was transurethrally resected in all boys. Continuous incontinence was observed in two of four children who had been operated on for the bladder neck. There was no spontaneous improvement of the refiux after valve ablation. The histologic finding of the non-functioning kidney with massive refiux was dysplasia. The results of the management of the dilated ureters through valve resection, temporary diversion or uretero-vesiconeostomy were not all satisfactory. As the temporary diversion, the ring ureterostomy was most effective. This method requires no indwelling catheter, and the operative procedure is relatively easy for younger children. Some pathway for urine fiows to the bladder remains, which prevents the bladder from defunctionalization. Because of the thickness of the bladder wall and the hypertonic intravesical pressure it is emphasized, that neostomy is not the initial choice of operation in this entity.抄録全体を表示PDF形式でダウンロード (2529K) -
渡辺 芳夫, 伊藤 喬広, 杉藤 撤志, 長屋 昌宏, 新実 紀二, 山田 昂, 石黒 士雄, 古川 博通, 奥川 恭一朗, 堀沢 稔, 鈴 ...原稿種別: 本文
1982 年 18 巻 1 号 p. 217-222
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーEsophageal atresia with the proximal tracheoesophageal fistula is very rare. Two cases have been experienced at our hospitals. In the first case who died of pneumonia on the 9th day after admission, a proximal tracheoesophageal fistula was discovered at autopsy. In the second case, there were no specific symptom and sign suggesting the proximal tracheoesopageal fistula. Only mild degree atelectasis in the right upper lobe had been seen until severe pneumonia occured at the third month. The proximal tracheoesphageal fistula was demonstrated by esophagography. A transcervical ligation of the fistula was performed immediately after diagnosis. In contrast, 6 cases of esopageal atresia without fistula (Gross's A type) in our experience had never suffered from pneumonia or atelectasis before the radical operation. So, when pneumonia occures in a case with esophageal atresia without fistula, the proximal tracheoesophageal fistula shoud be examined by either esophagography or bronchoscopy. Ligation of the fistula seems less dangerous by transcervical approach than transthoracic approach. An adequate exposure of the fistula located above T-2 vertebra is possible by transcervical approach but an attention must be payed not to injure the recurrent laryngeal nerve.抄録全体を表示PDF形式でダウンロード (1400K) -
松岡 潔, 三原 康生, 伊藤 保憲, 岡野 和雄, 浜脇 光範, 大村 勉, 岩田 克美, 徳岡 裕文原稿種別: 本文
1982 年 18 巻 1 号 p. 223-230
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーA newborn male infant with a fist-sized anterior neck mass bulging to the right side, was admitted to our hospital soon after birth. He was spontaneously delivered after 35 weeks of gestation with a birth weight of 2,650g. There was no evidence of hydroairnios. Because the baby presentad with severe respiratory distress and marked cyanosis, intratracheal intubation was performed at once, and mechanical ventilation was started. Roentgenography showed a cervical mass of soft tissue nature without calcification, which caused no tracheal deviation. A thyroid scintigram demonstrated marked swelling of the right lobe of the thyroid gland including a cold area in it, suggesting a diagnosis of thyroid neoplasma. Laboratory data were within normal limits, and α-fetoprotein was normal under 1,000 ng/ml. CT scanning revealed several intracranial low density areas that seemed to have caused the respiratory distress. The mass was nodulated, partly solid and firm, partly cystic to palpation, and increased gradually in size. Operation was performed on the 23rd day after birth, and the mass was located in the right lobe and isthmus of the thyroid gland, and was easily enucleated. The patient's recovery was uneventful. Microscopic examination revealed multiple types of tissue representing the three germinal layers, including squarnous epithelium, glial tissue, bone and columnar epithelium. He has grown normally now, one year after operation. Twenty one cases of teratoma including ours were reviewed from the Japaneses literature.抄録全体を表示PDF形式でダウンロード (1353K) -
伊藤 寛, 岸川 輝彰, 山川 洋右, 可児 淳朗, 冨重 博一, 戸田 孝, 中島 龍夫, 上 敏明, 吉崎 聡, 荒井 昌之, 津田 洋 ...原稿種別: 本文
1982 年 18 巻 1 号 p. 231-237
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーA case of Klippel-Trenaunay-Weber disease in a 7 year old boy who presented with chronic ulcer and hypertrophy of the left leg, congenital arterio-venous fistula, elevated 0.2 saturation of venous blood, and hemangioma was reported. After recision of chronic ulcer and hemangioma, the cutaneous and subcutaneous defect was filled up with gastrocnemius muscle flap and was covered by skin graft. Postoperative course was uneventful with normal function of the left leg. The pathological diagnosis of this case was hemangioendothelioma, although the hemangioma of Klippel-Trenaunay-Weber disease usually shows a simple or cavernous hemangioma. The muscle flap technique which was preserved the cooperating skeletal muscle, is a useful method in children to expect the complete healing healing of chronic leg ulcer.抄録全体を表示PDF形式でダウンロード (2271K) -
原稿種別: 付録等
1982 年 18 巻 1 号 p. 238-
発行日: 1982/02/20
公開日: 2017/01/01
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日本小児外科学会悪性腫瘍委員会原稿種別: 本文
1982 年 18 巻 1 号 p. 239-262
発行日: 1982/02/20
公開日: 2017/01/01
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原稿種別: 表紙
1982 年 18 巻 1 号 p. Cover3-
発行日: 1982/02/20
公開日: 2017/01/01
ジャーナル フリーPDF形式でダウンロード (353K)