The electropotentials of the human urinary bladder were recorded by means of one needle electrode, which was transurethrally thrust into the bladder musculature under direct vision.
The recording of the action potentials was obtained by an electrocardiograph connected to push-pull pre-amplifier.
1) The unipolar needle electrode method which was used was easier to apply, and gave less artefact than other methods in which bipolar blunt electrodes were used.
2) Electropotential changes in the normal urinary bladder were found to be constant in frequency (regularly 3 per minute). There was observed a wave which consisted of diphasic slow potential (i. e. A and B), like the one which Boyce obtained.
When the electrode was thrust into the bladder muscle at a point 1cm above and 1cm medial to the ureteral orifice, the duration and the electromotive force of this diphasic wave were:
A. 1.2-1.9 seconds (average 1.4 seconds) 0.27-0.38mV (average 0.32mV).
B. 2.0-4.2 seconds (average 3.1 seconds) 0.27-0.43mV (average 0.35mV).
B was larger than A both in electromotive force and in duration. Changing the point of inducement caused some deviation of the wave form, but the frequency of the wave was not changed.
In the recording of the same person with the same inducement, the variations of electromotive force and duration were small.
3) This diphasic slow potential had no direct relation with the peristaltic movement of the ureteral orifices.
4) By stimulation with parasympathomimetic drugs (such as Urecholin), the waves became more frequent and increased their electromotive forces, while sympathicolytic agents (such as Banthine) or lumbar anaesthesia reduced the bio-electric activity of the bladder.
5) (a) In the hypertonic neurogenic bladder, the rhythm of the waves was increased and very irregular, and in electromotive force, A wave was often larger than B. The variety of the wave form in the same person was remarkable, especially in the autonomous neurogenic bladder.
(b) In the hypotonic neurogenic bladder, both frequency and electromotive force were reduced. Only one or two waves occurred in 3-5 minutes recording, and the apparent diphasic wave became difficult to observe. In the cases of bladder paralysis after radical operation for rectal or uterine cancer, the same results were observed.
6) In the obstruction of the lower urinary tract (prostatic hyperplasia and other diseases), It was found that increase and decrease of frequency and electomotive force were variable according to the state of the detrusor muscle which was compensatory hypertrophic or atrophied, but the variety of the wave form in the same person was not found.

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In paper I of this series, it was reported that the function of the autonomic nervous system examined with the pharmacodynamic tests and mechanical tests, was in the state of hypertonia of para-sympathetic nervous system and hypotonia of sympaticotonic state two weeks after the removal of tuberculosis kidney.
In the present paper, serum calcium and potassium, which have been considered to have close relation with the function of the autonomic nervous system, were estimated in 20 renal tuberculosis patients before and three weeks after the removal of tubeculous kidney. The results were as follows:
1) In healthy adults (male: 10, female: 10), amount of serum Ca was 10.41±0.16mg/dl, K, 18.98±0.54mg/dl and K/Ca, 1.80±0.02.
2) In unilateral renal tuberculosis patients (male: 7, female: 13), Ca was 9.27±0.64mg/dl, K, 21.84±0.88mg/dl and K/Ca, 2.40±0.19.
With the advance of tuberculous changes in the kidney, serum Ca tended to decrease, on the other hand, K ahd K/Ca, tended to increase. Three weeks after the removal of tuberculous kidney, serum Ca returned to the normal amount, and K and K/Ca approached to the normal degree.
3) In renal tuberculosis, serum Ca tended to increase, on the other hand, K and K/Ca tended to decrease by the injection of adrenalin, and these changes were more conspicuous three weeks after the removal of tuberculous kidney. When pirocalpin was injected, serum Ca tended to decrease both before and after, irrespective of the removal of tuberculous kidney. However, K/Ca tended to decrease before the removal and to increase after it.
4) In many of genito-urinary tuberculous patients, those who had a higa K/Ca were more likely to have vagotone adrenalin reaction on the curve of the blood pressure after adrenalin injections, and those with a low K/Ca were more likely to have sympathikotone adrenalin reaction.

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Activity of serum cholinesterase (abbreviated to ChE) was estimated on 14 unilateral renal tuberculosis patients (male: 10, female: 4, ages: 17-58), 5 tuberculous epididymitis (ages: 15-40) and 20 healthy persons (male: 9, female: 11, ages: 20-37) as the controle group by means of modified Michel's method. The results were as follows:
1) Serum ChE activity in healthy persons varied from 0.7 to 1.1 and had an average value of 0.86±0.06.
2) Serum ChE activity in renal tuberculosis patients varied from 0 to 1.1 and had an average value of 0.55±0.22. It was normal only in 21.4% of the patients and was extremely low (less than 0.3) in 42.9% of the patients.
It seemed to decrease as a result of the influence of the destruction of tuberculous kidney, disturbance of the renal function, increase of the blood sedimentation rate and secondary disturbance of the liver function.
3) Three weeks after removal of the affected kidney, 64.3% of renal tuberculosis patients had normal activity of serum ChE and no case showed less than 0.3 of ChE activity. Parallel relation was observed between restoration of renal function and that of serum ChE activity.
4) Serum ChE activity of renal tuberculosis patients was not influenced by the injection of epinephrin, but apparently decreased by the injection of pilocarpin.
5) 40% of tuberculous epididymitis patients had normal activity of serum ChE and the remaining 60% of them showed a slight decrease of it. The average value was 0.76±0.17.

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Comparing retropubic with suprapubic prostatectomy, when a person with adequate skill performs the retropubic, it brings more satisfactory result from the point of view of the complications, convalescence and operative intervention.

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