The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
Volume 50, Issue 9
Displaying 1-5 of 5 articles from this issue
  • Keiichi Matsumoto
    1959 Volume 50 Issue 9 Pages 865-901
    Published: September 20, 1959
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
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  • Toshiyuki Matsumura
    1959 Volume 50 Issue 9 Pages 902-937
    Published: September 20, 1959
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
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  • Shigefumi Nishikawa
    1959 Volume 50 Issue 9 Pages 938-966
    Published: September 20, 1959
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Not a few cases of urologic diseases encountered demand us more precise analysis of individual renal function, when ICT and IVP are the only means available at the present time for this purpose. Various renal clearance tests with their appreciation of total kidney function have been thought to apply to serve to evalute individual renal function only to fail because of the difficulty in obtaining separate urine. There are some reports concerning the study of unilateral renal function using Garceau or Woodruff catheter and others.
    Here I introduce now method, balloon catheter I have devised and named to solve the problem obtaining pure separate urine, and present the results of renal clearances measured on normal and diseased kidneys with the aid of this catheter,
    1) The average values of individual renal clearance on normal kidney are CSTS R. 49.6ccm/min. L. 53.1ccm/min., C creatinin R. 45.7ccm/min. L. 49.8ccm/min., CPAH R. 255.4ccm/min. L. 269.9ccm/min., CPSP R. 245.9ccm/min. L. 252.5ccm/min. and F.F. 0.19 in both side, in adult male, CSTS R. 45.2ccm/min. L. 46.7ccm/min., C creatinin R. 44.7ccm/min., L. 46.8ccm/min., CPAH R. 230.6ccm/min. L. 235.1ccm/min., CPSP R. 224.4cc/min. L. 230.5ccm/min. and F.F. 0.19 in both side, in adult female.
    In the urinary tract obstruction, RPF and CPSP are often decreased greater than GFR, and they decreased in parallel to each other when urinary infection was complicated. Elimination of passage disturbances was usually followed by recovery of clearance especially RPF and CPSP, although the recovery of GFR was less rapid in the passage impairement at the upper urinary tract than at the lower portion.
    3) In the cases of the upper urinary tract calculi, the clearance of healthy kidney suffered little iufluences from the diseased kidney and the decrement of GFR was greater in ureteral stone than in renal stone.
    4) Staghorn stone caused a significant decrease in clearance especially of RPF and CPSP except GFR in which the degree of decrease was not as great.
    5) Post operative recovery of clearance in pyeloplastied hydronephrosis was more or less under influence of compensatory function by the healthy kidney, however, Hinmann's theory on renal counter balance should not be placed too great an emphasis preoperatively.
    6) Parenchymal damage of the kidney manifested in general decrease of clearance, and in case of renal tuberculosis its decrease was in parallel with the extent of the lesion, and the clearance of the healthy kidney was influenced by the condition of the diseased kidney.
    7) Movable kidney revealed lowering in clearance especially the values of RPF and CPSP. Essential renal bleeding showed a decrease in RPF.
    8) Renogram of the separate kidney showed a high correlationship between RPF and 15min. value of PSP, RPF and TmPAH, TmG and Fishberg's urine concentration test, a relative correlationship between RPF and TmG, and TmPHA and TmG, no correlationship between RPF and 60min. value of PSP.
    9) Individual renal clearance test was more sensitive than ICT and IVP, and enough information was obtained by our method to establish accurate diagnosis and management.
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  • PART 1. THE DETERMINATION OF TOTAL NITROGEN AND AMINO ACIDS OF THE PROSTATIC EXTRACTS
    Junichi Omura, Eiichi Maruo
    1959 Volume 50 Issue 9 Pages 967-977
    Published: September 20, 1959
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Concerning the natures of the prostatic gland, our great interestings from the standpoint of research are (1) hormone dependence (2) secretory ability (3) easy growth of neoplasms.
    In this studies, the authors have undertaken a study of the chemical changes of the prostatic gland inquiring into whether there is any relation between hyperplasia and carcinoma.
    To make this study more comprehensive, the first, the authors made several extracts from the prostate gland by using water, ether, acetone and alcohol, and then, the second, the effects of hormones on the nitrogen contents was investigated.The total nitrogen was determined by Kjeldahl method and amino acids were also determined by paperchromatography, and the results were as followed.
    1. In hypertrophy of prostate, total nitrogen was 4.83-2.81mg (3.74mg) per 100mg wet tissue weights with no hormone therapy, 4.01-3.14mg (3.66mg) with dihydrostilbestrol therapy, 3.85-2.74mg (3.22mg) with testosterone propionate and androgen suspension therapy, 4.62-4.29mg (4.46mg) with diethyldioxystilben diphosphate therapy.
    2. In carcinoma of prostate, the total nitrogen was 3.94-2.18mg (3.08mg) with no hormone therapy, 4.18mg with castrayion and diethyldioxystilben diphosphate therapy.
    3. Solubility of extracts was also studied and found good results with water (over 10%), no solubility with ether and acetone, and much less with alcohol than water.
    4. Amino acids patterns were mostly the same in hypertrophy as well as in carcinoma of prostate, but the effects of castration on amino acids patterns could be found obviously and reduced amino acids were recovered by the administration of hormones.
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  • Yasushi Toyoda
    1959 Volume 50 Issue 9 Pages 978-999
    Published: September 20, 1959
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
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