The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
Volume 78, Issue 8
Displaying 1-21 of 21 articles from this issue
  • Masatoshi Moriyama
    1987 Volume 78 Issue 8 Pages 1295-1305
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    To elucidate the specific chromosomal abnormality and its role in human bladder carcinogenesis, chromosomal analysis by Qbands staining method was performed.
    Two human bladder cancer cell lines, T-24 and MGH-Ul, and tumor cells from 7 patients with transitional cell carcinoma of the bladder were analysed.
    Abnormalities of number 1 chromosome, as 1p+, 1p- and 1q- in T-24 cells, 1p- or 1q- in MGH-Ul cells were observed in all karyotypes analysed. Abnormalities of number 1 chromosome, as 1p-, 1q- and monosomy, were also shown in tumor cells from all bladder cancer patients analysed. Other anomalies, such as trisomy and tetrasomy, were found in some of chromosomes. Marker chromosomes were also found but their origin was not clear.
    These results suggest that the abnormality of number 1 chromosome might be associated with the carcinogenesis of human bladder cancer.
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  • Koji Suzuki, Chisho Yamaguchi, Katsuhito Miyazawa, Toshinori Taniguchi ...
    1987 Volume 78 Issue 8 Pages 1306-1310
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    The inhibitory effect of sodium copper chlorophyllin (SCC) on the formation, growth and aggregation of calcium oxalate crystals were estimated by the use of Coulter counter TAII in the dilute and whole urine system.
    In the dilute urine system, inhibitory activity of aggregation and growth was calculated from the change of the number and volume of crystals by seed crystal method. 1% volume of urine inhibited the aggregation and growth of added crystals at the final concentration of 0.01-1.0μg/ml.
    In the whole urine system after determining the metastable limit, the formation and growth of crystals precipitated in response to a load of sodium oxalate (30μM) were quantified. SCC had a strong inhibitory effect on the formation and growth at the concentration of 10-100μg/ml. 1% volume of urine after the load of SCC markedly increased the inhibitory activity of aggregation and growth of calcium oxalate.
    SCC therefore might have the possibility of treating the recurrent stone formers.
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  • A study of 133 surgically removed bladders by mapping
    Masao Kuroda, Eitetsu Kou, Hitoshi Hamada, Shigeru Saiki, Toshiaki Kin ...
    1987 Volume 78 Issue 8 Pages 1311-1318
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    One hundred and thirty three cystectomy specimens obtained between 1978 and 1984 during treatment of cancer of the urinary bladder were analyzed by mapping. From gross and microscopic examinations, the growth pattern, grade, stage, mode of spread and intramural vessel invasion were found to be closely related with each other.
    Most cystectomy specimens had evidence of diffuse epithelial abnormalities ranging from dysplasia to carcinoma in situ in areas adjacent to and/or distant from visible tumors. Carcinoma in situ associated with overt carcinoma was seen in 35 of 49 (71%) papillary tumors and in 30 of 48 (63%) nonpapillary tumors. Carcinoma in situ was more frequently seen in bladders containing high grade tumors than those containing low grade tumors. Dysplasia was frequently seen in bladders containing papillary tumors and was usually associated with carcinoma in situ; this suggests that dysplasia may develop to carcinoma in situ, also raises the suspicion that dysplasia may develop to papillary tumor without developing to carcinoma in situ.
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  • Hiroshi Hashimoto, Sunao Yachiku, Masayuki Nishihara, Shigeru Arima, S ...
    1987 Volume 78 Issue 8 Pages 1319-1322
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    The histochemical detection of prostate specific antigen (PA) was performed in three cases with primary or metastatic tumors to determine whether the origin of the tumor was prostate or not.
    case 1: There was adenocarcinoma in biopsy tissues from both prostate and bladder. Both tissues were PA-positive, indicating that the origin of the tumor was the prostate.
    case 2: There was adenocarcinoma in both prostate and bladder as in case 1. Both tissues were PA-negative, indicating that the origin was probably the bladder. Total cystectomy was performed and the pathological finding, mainly transitional cell carcinoma, supported the previous diagnosis.
    case 3: There was metastatic adenocarcinoma in biopsy tissue from inguinal lymphnodes. The tissue was PA-positive, indicating that the origin was prostate.
    The above mentioned, the histochemical detection of PA is a valuable adjunct to conventional histopathology in cases with a tumor extending in both prostate and bladder or a metastatic tumor.
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  • Shoji Hirano, Mitsuo Ohkawa, Haruo Hisazumi
    1987 Volume 78 Issue 8 Pages 1323-1329
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Freshly voided urine and four-hour-standing urine samples from five stone-formers associated with infection of the upper urinary tract were collected to investigate the possible role of urinary infection in agglomerating urinary crystalloid substances. A control group consisted of seven simple stone-formers and seven recurrent and multiple stone-formers of the upper urinary tract. The urine sample was filtered through a nuclepore filter, and then the agglomerates obtained were studied under scanning electron microscopy. Crystal agglomerates were small in size and number in the simple stone-formers. The sizes and numbers of crystal agglomerates in the recurrent and multiple stone-formers were bigger than those in the simple stone-formers. In the stone-formers associated with urinary infection, crystal agglomerates were combined with erythrocytes, fibrin, other organic substances and bacteria. And crystal agglomerates were larger than those of the control group. Bacteria seemed to play a special role as an adhesive agent for crystal agglomerates and/or organic substances.
    The results obtained suggest that urinary infection acclerates crystal agglomeration in the urine of stone-formers mainly through bacterial adherence or cohesion.
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  • A Scanning Electron Microscopic Study
    Shoji Hirano, Mitsuo Ohkawa, Haruo Hisazumi
    1987 Volume 78 Issue 8 Pages 1330-1336
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    To elucidate the role of bacteria in the stone growth, various kinds of surgical threads were immersed for four hours in urine samples of four upper urinary tract stone-formers associated with urinary infection. A control group consisted of three healthy volunteers, four simple stone-formers and four multiple and/or recurrent stone-formers. Compared with healthy volunteers and simple stone-formers, crystal and/or organic substances were markedly adhered to the threads in multiple and/or recurrent stone-formers. In urine samples of the stone-formers associated with urinary infection, a larger amount of crystals and/or organic substances had a tendency to stick more quickly to the threads. The adhesion of bacteria to the threads preceded that of crystals and/or organic substances.
    The results obtained suggested that bacteria could be one of the significant promoters in the stone growth by virtue of their adherent property.
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  • Part 1: A Functional Study
    Kei Matsuoka, Shogo Ueda, Hirosi Kunimi, Masami Murakami, Sinsi Noda, ...
    1987 Volume 78 Issue 8 Pages 1337-1344
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    To study the effects of percutaneous nephroureterolithotomy (PNL) on the kidneys, renal function was evaluated before and after PNL in 56patients (60kidneys) treated at our department.
    Renal function tests included determinations of NAG and BMG in separate urine samples, the clearance test, RI-dynamic study, and renal arteriography.
    Changes in urinary NAG, BMG, and differential Ccr showed that reversible glomerular and renal tubular disturbances were induced during the 6-hour period after PNL but disappeared after 12 hours to 1 week. The RI-dynamic study revealed no persistent impairments 1-2months postoperatively. In patients with obstructive stones complicated with hydronephrosis, renal function recovered after PNL. Renal arteriography showed no changes in the major vascular system. Though the evaluation period was relatively short, these results suggest that PNL is a safe procedure without serious effects on renal function.
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  • Yoshinori Mori, Masaaki Arima, Kenji Shimada, Hiroki Shima, Tomoyoshi ...
    1987 Volume 78 Issue 8 Pages 1345-1353
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Twenty patients with T2-T4 invasive bladder cancer and without distant metastasis were treated with combined cisplatin and radiation therapy. Total cystectomy after combined therapy was performed in 10patients and in another 10patients total cystectomy could not be performed due to various reasons. In cases of preoperative treatment combined therapy of 40Gy radiation and intravenous cisplatin administration (20mg/m2×5days) was performed. In non-cystectomy group combined therapy of 60Gy radiation and same dose of cisplatin as in cystectomy group. Pathological examination of cystectomized bladder in 10patients revealed down-staging (P<T) in 70% and no tumor (P0) in 40%. This results are better than those obtained with preoperative irradiation alone. Although the followup periods in noncystectomy group are insufficient for evaluation of this combined therapy, no recurrence of the tumor in the bladder is noted in 50% of the patients during the followup period of 3months to 2years and 3months. Side effects were not severe and well tolerated. This combined therapy of cisplatin and radiation was effective in the local control of the tumor but it was not so effective in the prevention of a distant metastasis because 35% of our cases developed distant metastasis after the treatment.
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  • Report 7: Dynamic cavernography
    Yasuo Kawanishi, Akio Imagawa, Susumu Kagawa, Kazuo Kurokawa
    1987 Volume 78 Issue 8 Pages 1354-1360
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    To diagnose the venous impotence, we performed a dynamic cavernography on 103patients with impotence. Almost all of them also underwent an erectilc function test with NPT an/or AVSS, a PBl calculation and a papaverine test. The results were as follows.
    1) In theree patients out of the 103 the test was terminated bccause of chest pain or discomfort in the penis. In llpatients out of the remaining 100, intracavernous infusion till 200ml/min failcd to produce an erection. In the remaining 89, satisfactory erections were achieved at flow rates of between 40 to 200ml/min and were maintained at 5 to 160ml/min.
    2) In 20 patients out of 98, a cavernography did not visualize any venous systcm after ercction, but did in the remaining 78. The average flow rate to produce and to maintain an erection in the former was significantly lower than the latter (Fig. 1). Because the veins were apparent not only in patients with high flow rates but also in men with low flow rates, the findings of cavernography alone were not useful for diagnosis of venous impotence, but could reveal the location of venous abnormalities.
    3) The patients who were evaluated as functional impotent by an erectile function test had lower flow rates than those who were evaluated as organic impotent (Fig. 2, 3).
    4) The flow rates of the patients who achieved satisfactory erection by intracavernous papaverine injection were sign4fficantly (p<0.001) lower than that of those who did not (Fig. 4, 5). The aecragc flwo rate and standard deviation to produce and maintain erection in the former were 80.8±29.25ml/min and 21.9±15.02ml/min, respcctivcy. We calculated the normal flow rates [NFR<(avcrage flow rate+2SD)] using these results. The normal flow rate to produce an erection was less than 140ml/min, and that to maintain it was less than 50ml/min. In 41 men out of 100, the flow rate to produce and/or to maintain were beyond the normal range, and we diagnosed them as venous impotent.
    5) No correlation was seen between the findings of dynamic cavernography and the results of PBl calculation.
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  • Takeo Kariba, Atsushi Toyoshima, Hidetoshi Satoh, Hitoshi Tsuchida, Ke ...
    1987 Volume 78 Issue 8 Pages 1361-1364
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Results of optical internal urethrotomy (OIU) on 64 patients during the last 42 months were reviewed. The patients subjected were all male and OIU alone was done on 28 patients and OIU combined with either TUR-P or TUR-Bn on 36 patients. The former group ranged in age from 17 to 82 years old(mean 47.6). The stenotic sites were bulbomembranous region in 23 patients. pendulous region in 2 and both regions in 3. Etiology was traumatic or iatrogenic in 7 patients, postinflammatory in 11 and congenital in 10.21 patients improved by OIU alone, 1 improved by metal sound dilatation following OIU and 2 with traumatic stenosis necessitated TUR following OIU and 4 remained in unfavorable condition. The latter group ranged in age from 44 to 88 years old (mean 65.9). The stenotic sites were bulbomembranous region in 27 patients and extensive (from membranous to pendulous) in 9. Etiologywas iatrogenic in 1 patient, postinflammatory in 29 and congenital in 6.26 patients improved by OIU alone and 9 patients necessitated metal sound dilatation. The remainder was not improved. In general neither postoperative deterioration nor intraoperative complications were encountered.
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  • I) Cases of Transitional Cell Carcinoma of the Prostate
    Kazuhiro Takai, Tadao Kakizoe, Ken-ichi Tobisu, Keiichi Matsumoto, Kiy ...
    1987 Volume 78 Issue 8 Pages 1365-1371
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Three cases of transitional cell carcinoma arising in the prostate were reported.
    Case 1 was a 66-year-old man, who was thought to be with multiple transitional cell carcinoma in the urinary tract. Cystoscopy showed no tumorous lesions in the urinary bladder, but two synchronous tumors were found in the distal urethra. Cystoprostatourethrectomy with pelvic lymph nodes dissection was performed, but he died of pulmonary metastasis seven months later, despite irradiation and chemotherapy. The pathologic diagnosis was transitional cell carcinoma in the prostate, pT4N3M0, grade 3.
    Case 2 was a 76-year-old man, presumably with primary transitional cell carcinoma of the prostate. Cystourethroscopy showed no paticular tumorous lesions. Cystoprostatectomy with pelvic lymph nodes dissection was conducted and the pathology revealed transitional cell carcinoma in the prostate, pT4N4M0, grade 2 with concominant undifferentiated adenocarcinoma of the prostate. He was additionally treated by chemotherapy but died of cancer two months after the operation.
    Case 3 was a 56-year-old man, who was supposed to be with prostatic involvement by transitional cell carcinoma of the urinary bladder. He had been previously treated for superficial bladder cancer at another institution but at the time of diagnosis at this hospital, no tumor was found in the urinary bladder. Cystopostatectomy with pelvic lymph nodes dissection was performed and pathology revealed transitional cell carcinoma in the prostate, pT4N0M0, grade 3 with carcinoma in situ in the prostatic urethra. He underwent urethrectomy eleven months later because of urethral recurrence but at present he lives without any evidence of disease.
    The findings in these three cases and adenocarcinoma of the prostate were compared.
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  • II) Cases with Prostatic Involvement of Transitional Cell Carcinoma of the Urinary Bladder
    Kazuhiro Takai, Tadao Kakizoe, Ken-ichi Tobisu, Keiichi Matsumoto, Kiy ...
    1987 Volume 78 Issue 8 Pages 1372-1378
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Primary transitional cell carcinoma of the prostate and the prostatic involvement by the transitional cell carcinoma of the urinary bladder are sometimes difficult to differentiate even in terms of histology. Moreover, the prostatic involvement by transitional cell carcinoma of the urinary bladder is more frequently observed than the primary transitional cell carcinoma of the prostate. Therefore, in this report, the characteristics of the prostatic involvement by transitional cell carcinoma of the urinary bladder was examined in 173 cystoprostatectomized specimens for bladder cancer.
    The prostatic specimens were examined by step sectioning and were divided into “no malignancy” group and “prostatic involvement” group.
    Significant clinical and pathological findings in the “prostatic involvement” group were; (1) dysuria was more frequently observed, (2) invasive carcinoma was more prominent, (3) urethral recurrence was more frequently seen. The above findings were also coincident with the charactristics of the primary transitional cell carcinoma of the prostate. From the case reports in the first report and their comparison with adenocarcinoma of the prostate, and transitional cell carcinoma of the urinary bladder, the origin and development of transitional cell carcinoma of the prostate, and the relationship with transitional cell carcinoma in the urinary bladder as well as multiple urothelial carcinoma in the urinary tract were discussed from the anatomic, embryonic and carcinogenic standpoint. From the practical, therapeutic view point, we admit the concept of primary transitional cell carcinoma of the prostate, but at the same time we must also think about the possibility that the case is a special type of transitional cell carcinoma in the urinary bladder or prostatic involvement by multiple urinary tract cancer. The most suitable treatment appears to be cystoprostatectomy with or without urethrectomy and pelvic lymph nodes dissection. When one-stage urethrectomy is not performed, it is mandatory to periodically check the possibility of reccurence in the urethra in these cases.
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  • I. Incidence, Symptoms and Laboratory Findings
    Yoshiaki Satomi, Yutaka Senga, Momokuni Fukuda, Mitsuru Nakahashi, Mas ...
    1987 Volume 78 Issue 8 Pages 1379-1387
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Clinical observations were done on 333 patients with renal cell carcinoma who visited us from January 1965 to December 1982. The results were as follows;
    1. The incidence of renal cell carcinoma doubled during these 10 years. The tumor was rare until the decade and marked the maximum incidence, about 2/3 of all cases, in the sixth and seventh decades (average age 59.4 years old). The tumor affected males more frequently than females with a sex ratio of 2.4:1.
    2. Gross hematuria was found in 226 of our cases (67.6%), microscopic hematuria in 34 cases (10.2%), pain in 74 cases (22.2%) and tumor in 145 cases (43.5%). The incidence of the triad of symptoms was 7.2% (24/333). Non-specific symptoms in the patients were fever in 97 cases (29.1%), weight loss in 51 cases (15.3%) and general fatigue in 39 cases (11.7%). Metastatic symptoms were seen in 40 cases (12.0%) and valicocele in 6 cases (2.6%).
    3. Elevated E.S.R. was found in 160 of 288 cases (55.6%), positive CRP in 186 of 308 cases (60.4%), elevated α2-globulin in 170 of 286 cases (59.4%), elevated LDH in 24 of 266 cases (9.0%), elevated AL-P in 50 of 285 cases (17.4%), hypercalcemia in 4 of 150 cases (2.7%), anemia in 53 of 318 cases (16.7%) and polycythemia in 2 of 318 cases (0.6%). Positive urine cytology was revealed in 22 of 170 cases (12.9%).
    4. Patients with weight loss, general fatigue, GI upset, elevated E.S.R., positive CRP, elevated α2-globulin, fever, anemia and no hematuria were classified more frequently to stage IV renal cell carcinoma than those without them. Therefore, these symptoms were considered as the signs of poor prognosis.
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  • II. Radiographic Appearance
    Yoshiaki Satomi, Yutaka Senga, Momokuni Fukuda, Mitsuru Nakahashi, Mas ...
    1987 Volume 78 Issue 8 Pages 1388-1393
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    A clinical and statistical study was made on radiographic appearance in 333 patients with renal cell carcinoma who visited us from January 1965 to December 1982. The results were as follows; 1. Of 298 cases of renal cell carcinoma, 26 (8.7%) contained rentogenographically visible calcium. Most pattern of calcification was nonperipheral type (21/26), and peripheral or combination type was rare. Five year observed survival rate in patients with calcified renal cell carcinoma was 43% and no significant difference existed in survival rates between patients groups with calcified tumors and those with noncalcified ones. 2. The commonest type of deformity on IVP in renal cell carcinoma was compression and/or displacement of calyces (200/294 cases). A non-functioning kidney was noted in 47 cases (16%). The tumor size of the non-functioning kidney tended to be large. The 5 year survival rate in patients with non-functioning kidney was not less than that with functioning kidney. 3. There were 221 cases (89%) with angiographically hypervascular tumors, 19 cases (8%) with hypovascular tumors and 7 cases (3%) with avascular tumors. The cases with avascular tumor were devided into low grade papillary type tumor (3 cases) and histological grade 4 tumor (4 cases).
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  • III. Operations, Operative Findings and Results
    Yoshiaki Satomi, Yutaka Senga, Momokuni Fukuda, Mitsuru Nakahashi, Mas ...
    1987 Volume 78 Issue 8 Pages 1394-1402
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    A clinico-statistical study was made on surgical operations performed in a total of 333 cases that were encountered over the period of 18 years from January 1965 through December 1982. The conclusion drawn from this study may be summarized as follows:
    1) Nephrectomy was performed in 284 (85%) and not performed in 42 (13%) of the 333 cases. In 7 cases (2%) the operation was unsuccessful, ending in failure to excise the organ for various reasons including adhesions of the organ. There were 6 operative deaths (2%). 2) Translumbar nephrectomy was performed in 87 (31%), transperitoneal nephrectomy in 172 (61%), thoracoabdominal nephrectomy in 22 (8%) and partial nephrectomy in 3 cases (1%). No significant difference existed in long-term results between patients undergoing translumbar and those undergoing transperitoneal nephrectomy, suggesting that a transperitoneal approach is not invariably nessary and that translumbar operation may suffice in some cases. 3) In 10 cases (3%) there was lymph node involvement of N1 Mo or N2 Mo, and it was ipsilateral in all cases. This has led us to believe in the validity of lymphnode dissection performed on the affected side alone. 4) In 42 cases (13%) there was invasion of the renal vein or inferior vena cava. This incidence figure is much lower than most of those reported previously, presumably because of our inadvertency in examining the organs resected. 5) Only 3% of the total tumors studied were what may reasonably be considered early tumors less than 3cm in diameter. Staging according to Robson's criteria showed that the tumor was 5cm or longer in diameter in the majority (74%) of stage I cases, contrary to the prevailing notion that stage I is tantamount to early cancer. It appears, therefore, that Robson's classification system is not appropriate for the staging of renal cell carcinoma.
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  • Teruhisa Ohashi, Takafumi Akagi, Shin Irie, Tsuneaki Obama, Yasutomo N ...
    1987 Volume 78 Issue 8 Pages 1403-1408
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Prostatic acid phosphatase (PAP), γ-seminoprotein (γ-Sm) and prostatic specific antigen (PA) were determined by double antibody radioimmunoassay and enzyme immunoassay in 97 patients with prostatic cancer (the untreated: 35, the treated: 62), 316 with prostatic hypertrophy, 41 with bladder cancer and 138 with other benign urological diseases to assess the clinical usefulness as a tumor marker.
    Positive rates of PAP, γ-Sm and PA levels were 74.3%, 73.1% and 79.4%, respectively, in patients with untreated prostatic cancer, while those were 2.8%, 12.5% and 12.3%, respectively, in patients with prostatic hypertrophy. Although the highest sensitivity was found in PA levels, the highest specificity was shown by PAP levels.
    A slight correlation was found between PAP and PA, but no significant correlation was present with γ-Sm.
    The positive rate in untreated prostatic cancer patients increased by the combination assay of these three markers, and moreover, different variations of these markers were noted with various therapies in prostaitc cancer patients. These data suggested that the combination assay of these markers was useful for diagnosis and monitoring of prostatic cancer patients.
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  • Hiroyuki Mitsuhashi, Akio Maru, Tomohiko Koyanagi
    1987 Volume 78 Issue 8 Pages 1409-1416
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    The findings of cytogenetic observation of exfoliated cells of bladder cancer patients was related to their clinical course.
    The exfoliated cells were obtained from bladder barbotage, then chromosomal observation was perforemed by direct method or short incubation method. Banding analysis with Quinacurine was also made for observation of structural changes when adequate chromosomes were available.
    Aneuploid cells were found in exfoliated cells from 6 of 11 patients who had the history of bladder cancer but with no visible current tumor. Three of these 6 patients were proven to be with histopathologically transitional cell carcinoma of the bladder in a few months period. The other 3 patients were observed closely.
    On the other hand aneuploid cells were found in the exfoliated cells from 7 of 10 patients with obviously visible tumor. All of these 7 patients were diagnosed histopathologically as having transitional cell carcinoma of the bladder. The other 3 patients were diagnosed histopathologically as having benign diseases.
    Banding analysis sucseeded in about 30% patients, and proved that apparant structural changes existed in chromosomes obtained from exfoliated cells. This result suggested that aneuploid cells obsereved in exfoliated cells were originated from cancer tissue.
    Our study suggests the possibility that this method could well serve as a new diagnostic tool for detecting bladder cancer in its preclinical stage.
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  • Tadahisa Matsuda, Masahito Saitoh, Masahiro Abe, Tetsuya Hashimoto, Hi ...
    1987 Volume 78 Issue 8 Pages 1417-1422
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Selective renal biopsy for renal tumor was performed in 10 cases in our clinic during the last 4 years. These cases were difficult to diagnose by the conventional procedures such as CT scan, sonography and renal angiography. Selective renal biopsy using interventional ultrasound revealed 6 cases of renal cell carcinomas, one case of papillary renal cell carcinoma, one case of transitional cell carcinoma, one case of angiomyolipoma and one case of membranoproliferative glomerulonephritis, providing important informations for the treatment. Neither needle tract seeding nor complication was caused by biopsy in the series.
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  • REVIEW OF 125 CASES
    Akira Wakatsuki, Shunji Nisio, Osamu Kamei, Tsuyoshi Oda, Kazuo Nakasu ...
    1987 Volume 78 Issue 8 Pages 1423-1428
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    We describe 125 cases of a percutaneous approach to stones at our hospital for the 2 years between June 1984 and July 1986.
    As a rule, we performed these procedures in one session, but, several procedures were necessary in 34 cases. Open surgery was performed on 11 cases (in 5 cases firmly impacted ureteral stones could not be extracted, in other 5 cases nephrostomy construction failed and in the last one case nephroscope deviated from the nephrostomy tract in the procedure). Although residual stones were found in 15 cases (9-caliceal stones and 6-small stones), target stones were successfully treated in all cases.
    We described in the first report that some ureteral stones could not be treated by percutaneous approach when they firmly impacted in the ureter. In our series, however, ureteral stone patients occupied 71 of the 125 cases. Therefore, it was very important how to extract ureteral stones. Thirty-two ureteral stones were easily moved into the renal pelvis (in 12, by only ureteral catheterization and in 20, by flushing through the ureteral catheter). But, because stones were firmly impacted in other 39 cases (basket catheter or other forceps was used in 29 cases and ultrasound destruction was done in 10 cases).
    Before the use of the ureterorenoscope, we performed open surgery to extract firmly impacted ureteral stones. But we have become to be able to extract such a stone, using the ureterorenoscope through the nephrostomy tract.
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  • Miki Shiramizu, Noboru Nakajima, Hideshi Miyakita, Yoji Katsuoka, Teii ...
    1987 Volume 78 Issue 8 Pages 1429-1434
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Multilocular cystic nephroma (MCN) is an uncommon manifestation of renal mass, and its pathogenesis is unclear and has been debated. We treated an adult female case of MCN which was by enucleation of the cystic mass. In the literatures many cases of MCN had been undergone nephrctomy, because of difficulty to confirm the preoperative diagnosis or to distinguish from malignant tumor. MCN has the unique gross appearance, therefore it is not so difficult to make the diagnosis using recently developed diagnostic imaging technique. However, there are few reports of MCN associated withmalignancy. Since MCN is essentially a benign lesion, it is appropriate and reasonable to manage by conservative surgery as far as possible.
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  • A CASE REPORT
    Masayuki Maruoka, Takehiko Miyauchi, Tadao Nagayama, Takeichiro Kuwaha ...
    1987 Volume 78 Issue 8 Pages 1435-1437
    Published: August 20, 1987
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    A case of omental-mesenteric myxoid hamartomas is reported.
    An eleven year-old girl was admitted with abdominal mass. Ultrasonography and CT demonstrated a movable abdominal tumor of 87×87×60mm. During operation, multiple nodular tumors of omentum, mesentery and Douglas cul-de-sac were found. The largest tumor extirpated weighed 280g. Pathological diagnosis was omental-mesenteric myxoid hamartomas.
    This disease was characterized by multiple nodular tumors of omentum and-mesentery with good prognosis.
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