The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
Volume 56, Issue 12
Displaying 1-5 of 5 articles from this issue
  • PART II. SELECTIVE RENAL ANGIOGRAPHY IN VARIOUS UROLOGICAL DISEASES
    Ryuichi Kitagawa
    1965 Volume 56 Issue 12 Pages 1271-1285
    Published: December 20, 1965
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    One hundred and twelve trials of selective renal angiography were carried out during September 1963 to April 1965 with the failure of 11 times (10%). Main causes of failure were for tortuous aorta and iliac artery due to arteriosclerosis and for stricture of renal artery.
    The contrast media utilized were mainly 60% Conray which had low viscosity available for the rapid injection.
    In this paper presentation is concerned to various renal diseases especially to renal tumor cases, showing the interesting films and discussing the characteristic findings and diagnostic features.
    Abundant pathological vessels, A-V fistulas and pooling were usually demonstrated in malignant renal tumors. Tumor stain in nephrographic phase was irregular and in which pathological artery and pooling were evidently remained. Rapid appearance of venous phase was common.
    Benign renal tumors on the contrary, showed no pathological vessels. In nephrographic phase filling defect with well defined borders was characteristic.
    Nephrogram in renal cyst revealed beak-shaped appearance (Fig. 18, 20) and in polycystic kidney revealed wormeaten cortex (Fig. 22, 25).
    Early changes of renal tuberculosis detectable in pyelography were not evident in angiogram.
    However, angiograms were useful in visualizing renal contour and in judging the parenchymal impairment in end stadium cases of hydronephrosis, contracted kidney, motal kidney and so forth.
    In discussion the author stressed the prevalence of selective renal angiography in the diagnosis of renal artery disorders and renal parenchymal changes especially in early diagnosis of renal tumors because of better visualization of small arterioles and nephrograms than in hithertofore abdominal aortography.
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  • I. EXPERIMENTAL AND CLINICAL OBSERVATIONS ON BLADDER REGENERATION
    Tetsuo Omoto
    1965 Volume 56 Issue 12 Pages 1286-1301
    Published: December 20, 1965
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Regenerative ability of the bladder was studied experimentally and the review of the literature about the clinical application of the bladder regeneration was presented.
    In the group of the subtotal cystectomy, a new bladder was reconstructed from the trigone which had been left in place and no influence of the procedure on the kidney function was observed.
    In the group of the total cystectomy, regeneration of a new bladder was not noticed and in all survivor the formation of urinary fistula, incontinence and disturbance of kidney function occured.
    On the review of Japanese literature, only 5 successful cases of eighteen were reported after subtotal cystectomy, 2 of 20 after total cystectomy. These results were similar in the world literature.
    According to the above-mentioned experimental and clinical results, this procedure should not be applied clinically as bladder substitution at present, even if the bladder has a regenerative ability after subtotal cystectomy.
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  • 1. THE FIBRINOLYTIC ACTIVITY OF HAEMATURIA
    Hajime Sugiura
    1965 Volume 56 Issue 12 Pages 1302-1314
    Published: December 20, 1965
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    The fibrinolytic activity in haematuria, especially the effect of blood component on fibrinolytic activity of urine were investigated. The fibrinolytic activity in urine were determined by means of unheated and heated fibrin plates prepared by “method of Astrup and Müllertz”. The fibrinolytic activity of crude extract of urine is called as “FA in urine” and that of the extract of urine absorbed by 2M KSCN is called as “Act in urine”.
    The results are summarized as follows:
    1) In normal human blood both Act and FA were not determined.
    2) Act in urine were not recognized in normal urine but some FA in urine were determined.
    3) Urine samples were obtained from two patients with prostatic hypertrophy, two bladder tumors and one essential renal bleeding.
    4) In each case, the level of the FA in urine were relatively high within normal limit.
    When haematuria developed, the level of FA in urine were decreased; but as soon as urine became clear, the value of that converted to the patient own level.
    5) Whereas, Act is urine were not recognized in the urine if the urine is not haematuria, but it immediately appears upon haematuria.
    6) In one patient, who had bladder tumor followed by the uremia with generalized tumor metastasis, there had been no FA in urine, but some Act is urine for 7 days just before his death. These phenomena were unable to be explained with the fact of haematuria.
    7) On the haematuria by ureteral catheterization, especially Act in urine elevates than the usual elevation of the values of FA in urine.
    8) In the whole blood is added into the urine, the level of FA in urin decreases slightly, conversely Act in urine developes.
    9) Addition of euglobulin to normal urine made a same effect with whole blood.
    10) From those facts, it is thought to me that proactivator and activator in the blood would be activated and would produce active activator and active plasmin.
    Therefore we must consider the influence of blood components for the estimation of the fibrinolytic activity in haematuria.
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  • 2. THE FIBRINOLYTIC ACTIVITY IN URINE BY SEPHADEX GEL FILTRATION
    Hajime Sugiura
    1965 Volume 56 Issue 12 Pages 1315-1322
    Published: December 20, 1965
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    In this paper fractionations of optical density of 280mμ. and fibrinolytic activity by Sephadex gel filtration in human urine are studied.
    The results are summarized as folows:
    1) Optical density of normal urine, haematuria and normal urine added with whole blood were determined and that could be divided into three main peaks respectively.
    2) Fibrinolytic activity of normal urine and haematuria could be divided into apparently two different main patterns. The first pattern of fibrinolytic activity of normal urine was weaker than the second pattern, but in haematuria the first pattern was stronger than the second pattern.
    3) Fibrinolytic activity in the normal urine added with the whole blood of same person gave a single pattern and it was not divided into two patterns.
    4) If some blood is mixed with urine, this blood change a proper fibrinolytic activity of urine, so fibrinolytic activity in the urinary tract is influenced with the condition of the urinary disease.
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  • I. ON CONNECTION BETWEEN “BRADYKININ” AND FIBRINOLYTIC ENZYM SYSTEM
    Namio Kono
    1965 Volume 56 Issue 12 Pages 1323-1332
    Published: December 20, 1965
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    I have previously reported some clinical and experimental studies on the participations of fibrinolytic enzym to the nonspecific urinary tract infections.
    On the development of non-specific urinary tract infections, it is very important that we consider the various endogenous conditions prepared on a side of the host alike the activity of bacterium.
    Therefore, I taked up a problem around bradykinin which may be related to the inflammations.
    “Kinin” is a general term for the peptide having a biological activity which is developed by the action of proteolytic enzym to the plasma α-globulin, and kallikrein, plamin and trypsin are regarded as the representative substances of kinin releasing enzym.
    But a problem on these releasing mechanism and biological meaning and the balance of these enzym system still remain to be explained.
    I consequently studied on the effects of bradykinin as a typical kinin to the fibrinolytic system and the developing mechanism of urinary tract infections in the rabbits.
    1. In case of the administration of bradykinin over 10γ in Freund's incomplete adjuvant, the plasminogen increased or the inhibitor decreased. Bradykinin produced some effects on the fibrinolytic enzym system.
    2. The experimental urinary tract infections maintained by the sensitizing treatment with bradykinin.
    3. Any immunoreaction with bradykinin could not be demonstrated by the serum, precipitin and complement reactions.
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