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Volume 49, Issue 1
Displaying 1-5 of 5 articles from this issue
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Kunisuke Isei1958 Volume 49 Issue 1 Pages 1-11
Published: 1958
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSPolarizing microscope studies on 98 cases of the lower urinary calculi including 82 cases of vesical calculi were made preparing 122 sheets of thin slices to observe the components and constructions of the calculi. Especially, the considerations were made on the nuclei of the vesical calculi.
(1) Chemically, uric acid was the most readily recognized component and calcium oxalate, MgNH4PO4·6H2O, amorphous-like substance (mainly apatite) were followed by polarizing microscope examination. As the components of nuclei, calcium oxalate which might fall in the bladder from the upper urinary tract were most commonly observed.
(2) Although the nucleic substances of the vesical calculi were mainly calcium oxalate and amorphous-like substance, many other substances were also observed as nuclei, so that all of the vesical calculi would not seem to be secondary calculi.
(3) The stages of growth of vesical calculi were mostly identical. They grow gradationally and we have been observed, between each stages of growth, the dissolved space, suggesting naturally dissolved in many cases.
(4) Observations on calculi may be conveniently divided into two places: the nucleus and perimeter. When uric acid and MgNH4PO4·6H2O were observed as nuclei, the same substances were crystalized off at the stages of growth in bladder, while calcium oxalate was found as nuclei, the different substances were produced.
(5) Four cases of foreign bodies stone (clayon, paraffin mass, grass shaft and needle) were observed. In the needle, the main component were CaC2O4·H2O, MgNH4PO4·6H2O and amorphous-like substance, while the rest of them were MgNH4PO4·6H2O and amorphous-like substance.
(6) Nine cases of urethral calculi and 7 cases of prostatic calculi were observed. Two cases of 7 of prostatic calculi were seemed to be consisted of pure apatite crystal.View full abstractDownload PDF (5189K) -
Kunisuke Isei1958 Volume 49 Issue 1 Pages 12-20
Published: 1958
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSThe studies were made on a series of rats with foreign bodies placed in the bladder and the incidence of calculous formation was observed by polarizing microscope and, moreover, the same experiments were made on rabbits and analyzed by X-ray diffraction.
The influence of glucuronic acid upon calculous formation was also studied on rats.
(1) Struvite (MgNH4PO4·6H2O) was observed alone when the fragment of magnesium ammonium phosphate was used as nucleus. When calcium oxalate was used as nucleus, the components of the foreign bodies stones and all other daughter stones were Newberyite. And also, on the cases of uric acid stones, all of them were dissolved, but Newberyite were produced in a few samples.
(2) Calcite was the main component on rabbits vesical calculi, but Struvite was also observed on the case of silk gut nucleus.
(3) The formation of foreign bodies calculi of bladder in rats was prevented by the administration of glucuronic acid, but no effective influences could be expected on human urinary calculi which were used as nuclei.View full abstractDownload PDF (7215K) -
APPLICATION OF CESIUM137 NEEDLES AND YTTRIUM90 COLLOID TO THE MALIGNANT TUMORS OF THE UROGENITAL ORGANSHidekazu Hoshino1958 Volume 49 Issue 1 Pages 21-49
Published: 1958
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSThe author applied the Cs137 needle or Y90 colloid, which were made available by courtesy of the Department of Radiology of our school, to the treatment of genito-urinary tumors and obtained results as follows:
No serious complications were noticed. But irradiation cystitis was innevitable, especially in case of Cs137 stinging. ACTH was found to alleviate the cystitic symptoms and prevented the occurring of fibrosis.
The author observed the histological influences of Cs137 and Y90 on the urinary bladder or prostate of mongrel dogs and counted the distribution of Y90 in the regional lymphatic glands and various organs.
Summarizing the clinical and experimental cases, the principal histological changes with these radio-isotopes are successively, an immediate acute inflammation, hyaline degeneration after a week, fibrotic proliferation in one to three months and later fibrous replacement. Generally speaking, these changes coincide with the report of Berg and Bulkley who used Au198.
It may be concluded, therefore, that the present status of treatment with radio-isotope necessitates its use in combination with operation therapy because of the incomplete distribution of isotopes to the regional cancerated lymphatic nodes.View full abstractDownload PDF (9611K) -
Kunio Azuma1958 Volume 49 Issue 1 Pages 50-73
Published: 1958
Released on J-STAGE: July 23, 2010
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Harushige Nakagome1958 Volume 49 Issue 1 Pages 74-96
Published: 1958
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSOne hundred fifty-nine cases of prostatic calculi in the Japanese literature, including author's nine cases, were reviewed. On the basis of collected cases, much importance should be attached to the history of gonorrhoea and existence of urethral stricture concerning the pathogenesis of this disease. As to treatment, Chute's method of total prostatectomy was recommended, by which the author obtained good results in his all cases.
Normal prostatic tissues obtained from 81 cases, ranging in age from a month to ninety years, were histochemically studied. Corpora amylacea, homogeneous in stain, was found for the first time in a specimen of 16 years boy, while ordinary striated types were demonstrated increasingly with age in specimens of over 32 years. Calcium-deposit was not found in the young homogeneous type, but abundant in the nucleus or concentric striations of the adult type. In all cases D. N. A. was negative and glycoprotein positive.
A series of chemical analysis were undertaken to clarify the structure of prostatic calculi. The results obtained are as follows;
1. The principal constituents of the primary prostatic calculi were Ca3(PO4)2+6 CaHPO4.
2. Spectroanalysis revealed less content of magnesium in the prostatic calculi than urinary calculi. This signifies less participation of inflammation in the development of the former calculi.
3. X-ray diffraction analysis demonstrated less crystallisation of the prostatic calculi.
4. The content of the organic substances in the prostatic calculi was found to bee by far more abundant than urinary calculi. This fact was clearly illustrated on the infrared spectrophotogram.
5. Qualitative analysis of the amino-acids in the calculi was done with the aid of paper-chromatography. Tryptophan and phenylalanin which were not found in the renal calculi were demonstrated in the prostatic calculi.
6. Polysaccharide in the calculi was identified chromatographically as chondroitin sulfuric acid.
On the basis of the findings mentioned above, the author discussed his opinion on the pathogenesis of the primary prostatic calculi and made good a deficiency of Moore's theory which appeared in 1936.View full abstractDownload PDF (6756K)
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