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Volume 71, Issue 3
Displaying 1-9 of 9 articles from this issue
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I. Comparative Studies Between Water-Cystometry and CO2 CystometryToshiyuki Mizuo, Takehisa Ushiyama, Hirohisa Takeda, Seigo Hiraga, Hir ...1980 Volume 71 Issue 3 Pages 223-231
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSCO2 cystometer (DISA 21G45 cystograph) was used in 153 patients for about one year and 6 months. 23 patients of them was compared with the results obtained with fill water cystometry and rapid fill CO2 cystometry. In 21 patients the cystometric pattern was the same for both methods. In 2 patients we found uninhibited contraction with watercystometrogram but not with CO2 cystometrogram. The medium volume at first desire to void was larger in watercystometrogram than in CO2 cystometry in the normal type of the bladder, but in cases of the spastic type the volume was almost the same for both methods. Bladder volume was larger in watercystometry than in CO2 cystometry in the normal and flaccid types, but in cases of the spastic type the volume was the same. We concluded that the CO2 cystometry was safer, simpler and more time-saving than watercystometry.View full abstractDownload PDF (4553K) -
I. Their Relationship to Renal FunctionsNamio Kono, Takashi Mizokami, Akira Wakasugi1980 Volume 71 Issue 3 Pages 232-238
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSWe have already reported that platelets and/or cell elements originating from platelets are always involved in urine of normal and sick persons. (The small bodies were termed “platelet-like bodies in urine”-U-PLB). Transmission electron micrographs of the small bodies fixed with glutaraldehyde and osmium often showed the dense body which is considered as the storage organelle of 5-hydroxytryptamine (5-HT).
There is not an article on the separate determination of 5-HT in the urinary sediment and supernatant, nor an article on the relation between 5-HT in urine and blood and the renal function.
In 32 cases having various renal functions (Ccr; 68.8±31.7, range; 126.9-11.2ml/min) the endogeneous creatinine clearance test (Ccr) for 24 hours was done and the values of 5-HT in daily urine and blood were assessed.
The average values of 5-HT in the urinary sediment and the supernatant were 57.88μg/dl and 33.35μg/dl respectively and in 23 cases out of 30 cases (77%) the former was higher than the latter. These examinations of 5-HT suggested that platelet-like body is present in urine.
The average values of 5-HT in the whole blood and the platelet rich plasma (PRP) were 11.71μg/dl and 23.94μg/dl respectively and were lower than those in the urinary supernatant. The values of Ccr were significantly related to the values of 5-HT in the urinary supernatant and the daily excretion values of 5-HT in urine, and the values of 5-HT in the whole blood were significantly related to the values of C5-HT. In 4 cases out of 32 cases (12.5%) the values of 5-HT in the whole blood were higher than those in the urinary supernatant, and all of them were suffering from chronic glomerulonephritis. Therefore, we should give carefull consideration of the renal function to the investigation of 5-HT in urine. The values of urinary 5-HIAA were significantly related to the urine volumes, but those were not related to the values of 5-HT in urine and in blood and the renal functions.View full abstractDownload PDF (913K) -
Asymptomatic Bacteriuria of Schoolchildren in Chiba City and Urinary Tract Infection in Outpatient Children of Department of Urology Chiba UniversityKosaku Yasuda, Takashi Katayama, Hiromi Iwama, Toshiki Hama, Tomoyuki ...1980 Volume 71 Issue 3 Pages 239-247
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSThe clinical and laboratory features of urinary tract infection were studied on symptomatic as well as asymptomatic children.
Among 77950;, 68(0.09%) had significant bacteriuria in asymptomatic schoolchildren in Chiba City in 1977. E. coli was found to be the main cause. Radiological examination was performed in 13 of the 68 children. Vesicoureteric refluxes and neurogenic bladder dysfunction were found in 8(61.5%) children. Follow-up study six month later revealed that 56 children were under medical care and 47(84%) were free from infection.
On the other hand, symptomatic urinary tract infections were studied on outpatient children visiting the Department of Urology, Chiba University, during the period of 1975 to 1977. Among total 1327 outpatient children, 215(16.2%) revealed to have urinary tract infections (cystitis: 82, vesicoureteric reflux: 24, pyelonephritis: 22, vulvitis: 19, neurogenic bladder dysfunction: 14, urolithiasis: 14, etc). Various organisms such as E. coli: 21, Krebsiella: 5, Enterobacter: 3, Proteus: 2, Staphylococcus: 2 were isolated from these patients.View full abstractDownload PDF (2749K) -
Instillation of Ethanol into the Pituitary on Advanced Prostatic CarcinomaShinichi Takeuchi, Kiyonobu Tari, Fumikazu Takeda, Taku Fujii, Ryuji T ...1980 Volume 71 Issue 3 Pages 248-256
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSChemical hypophysectomy—Instillation of ethanol into the pituitary—was carried out according to the method of Moricca with slight modification in 6 patients with prostatic carcinoma; once for 5 patients and twice for another.
All of them had suffered from intractable pain caused by widely spread bony metastasis.
Ethanol in total amount of 1.6 to 2.4ml was injected into the pituitary through less than three needles which were previously confirmed as being introduced into the sella turcica via a nostril route under televised fluoroscopy in lateral and AP views.
The results of chemical hypophysectomy were successful; complete relief of pain in 3 patients and marked improvement of pain in other 3 patients. The pain relief continued for 4 to 16 months.
The effect of the treatment on carcinoma tissue itself was monitored by serum acid phosphatase, which transiently increased in most patients immediately after the treatment and then markedly decreased in 4 patients, and normalized in one of the 4 patients. There were neither lethal side effects nor complications.
One of the major side effects was diabetes insipidus caused by destruction of posterior pituitary, but this was well controlled recently by indomethacine administration.
In conclusion, chemical hypophysectomy is obviously effective for improvement of clinical conditions, but the effect of the treatment on carcinoma tissue itself remains to be studied.View full abstractDownload PDF (5846K) -
Masao Osafune, Hiroshi Ito, Masaaki Arima, Minoru Matsuda, Shutaro Miz ...1980 Volume 71 Issue 3 Pages 257-263
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA case report of primary carcinoma in situ of the bladder is presented.
A 63-year-old man with complaints of urinary frequency and dysuria was seen at the Osaka University Hospital in January, 1978. The patient gave hematuria on a microscopic test, but no distinctive abnormality in the urinary tract on X-ray examination except mucosal hyperemia at the left lateral wall of the bladder on a cystoscopic test. TUR biopsy of the bladder was done because a urinary cytological test showed persistently positive results. On histological examination, denuded surface, submucosal edema, teleangiectasis and marked cellular infiltration were observed. These findings were suggestive of chronic cystitis.
Although the patient continued to give the positive cytology test, there was no abnormality on X-ray and cystoscopic tests even after a 4 months follow-up. However, histologic proof of carcinoma in situ of grade IV transitional cell carcinoma was established after analysis of the repeatedly biopsied specimen, and total cystectomy with ileal conduit urinary diversion was performed on the 12th of July, 1978.
Histological examination of the dissected bladder revealed carcinoma in situ in almost all area of the bladder mucosa and in the prostatic urethra. Section of the prostate revealed intra-ductal and intra-acinal involvement by the malignant cells that were similar to those seen in the bladder, and the prostatic stroma was also partially infiltrated. The cancer cells infiltrated through the basement membrane of the prostatic acini, but not directly through the bladder mucosa.
Reviewing the literature on the bladder carcinoma in situ, the present case seems to be different from the type found in visible bladder cancer. Therefore, we propose to name it a “primary” carcinoma in situ of the bladder. The “primary” carcinoma in situ has a tendency to infiltrate into the prostate through the prostatic ducts, prior to its invasion to the basement membrane of the bladder, and is characteristic of developing directly from the stage O to the stage D.View full abstractDownload PDF (4921K) -
Report of a CaseTsuneharu Miki, Masao Kuroda, Hisakazu Kiyohara, Michiyuki Usami, Taka ...1980 Volume 71 Issue 3 Pages 264-272
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA case of primary prostatic carcinoid tumor is reported.
A 61-year-old man was hospitalized in October, 1976, because of dysuria, urinary frequency and perineal pain. There was no history of diarrhea, abdominal discomfort or flushing.
Physical examination revealed an enlarged, stony hard prostatic gland that was irregular in contour and consistency, giving the impression of carcinoma of the prostate. However, carcinoid tumor was diagnosed following examination of transrectal prostatic needle biopsy material.
Radiographically, a retrograde urethrocystogram demonstrated a trabeculated bladder and narrowing prostatic urethra, but the chest, skeletal system and entire alimentary tract were normal.
Routine laboratory data were within normal limits except for the serum serotonin level which was 345μg/l (normal level is under 125μg/l).
Pelvic evisceration with construction of an ileal conduit and preternatural anus was performed on November 11, 1976, and iliac lymph nodes were dissected.
Grossly, the tumor was solid and localized in the prostate, and there was scarcely normal prostatic tissue. Histologically, the tumor was composed of nodular solid nests, rossete-like structures and peripheral pallisading. Lymph nodes dissected showed the same structures. Histochemically, the tumor cells were positive for the argyrophil reaction by Glimelius silver stains, but negative for argentaffin reaction by Masson-Fontana silver stains. Electronmicroscopically, the tumor cells had characteristic secretory granules.
As a result, the pathological diagnosis of this tumor was determined as a primary carcinoid tumor of the prostate.
The patient received intravenously 5-FU for about one month after the operation. However, the clinical course of the patient was rapidly downhill, and he died of cachexia four months after the operation. Autopsy was not performed.
To our knowledge, this is the first case of primary prostatic carcinoid tumor reported in Japan.View full abstractDownload PDF (6724K) -
Yutaka Uchijima, Motohide Akutsu, Koichi Okada, Motoharu Komase1980 Volume 71 Issue 3 Pages 273-282
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA case of retrocaval ureter belonging to group V. by Nielsen's classification is reported. A 37-year-old man was admitted to our clinic with asymptomatic hematuria and proteinuria. The diagnosis of the retrocaval ureter was established by IVP, RP and venacavography. Excision of the posterior cardinal vein was performed. The postoperative course was uneventful. And, in our case, there was the hemiazygos vein as a continuation of the anomalous IVC, which ultimately entered the azygos vein. Confirmation of the retrocaval ureter requires techniques that simultaneously delineate both the ureter and the vena cava. Inferior venacavography combined with ureteral catheterization is usually employed. Computed Tomography enables us to demonstrate a retrocaval ureter. In many cases this simple noninvasive technique may eliminate the need for the more invasive methods formerly used.View full abstractDownload PDF (7860K) -
Report of a CaseMasao Kuroda, Tsuneharu Miki, Hisakazu Kiyohara, Michiyuki Usami, Taka ...1980 Volume 71 Issue 3 Pages 283-288
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA 38-year-old male who had urolithiasis due to partial deficiency of adenine phosphoribosyltrans-ferase was presented.
The patient who had a past history of urolithiasis was admitted with complaints of left flank pain in January 1978. Plain X-ray films revealed no calcific shadow. Intravenous pyelography and retrograde pyelography showed radiolucent stones in the left upper urinary tract.
On January 18, 1978, left ureterolithotomy was performed. Stone analysis with the infrared spectrum, the ultraviolet spectrum, the mass spectrum and the X-ray diffraction spectrum showed that these stones were composed of 2, 8-dihydroxyadenine. Erythrocyte hemolysate activity of adenine phosphoribosyltransferase in the patient was about 30% of normal. Our case seemed to be a heterozygote for adenine phosphoribosyltransferase deficiency.
In literature three cases of 2, 8-dihydroxyadenine stone accompanied with complete deficiency of adenine phosphoribosyltransferase have been reported. No case of 2, 8-dihydroxyadenine stone accompanied with partial deficiency of adenine phosphoribosyltransferase has been reported.
It is said that deficiency of adenine phosphoribosyltransferase was inherited as an autosomal trait. Erythrocyte hemolysate activities of adenine phosphoribosyltransferase in the patient's family are under investigtaion.
The patient is maintained under administration of allopurinol 300mg per day. There is no recurrence of urolithiasis a year after operation.View full abstractDownload PDF (2237K) -
Kazuo Suzuki, Atsushi Tajima, Kimio Fujita, Yoshio Aso, Satoshi Hiruma ...1980 Volume 71 Issue 3 Pages 289-294
Published: 1980
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA 41-year-old male was admitted with complaints of back ache and easy fatigability. Blood pressure was 150/60. Central obesity and buffalo hump were observed. Urinary 17-OHCS and 17-KS were increased. Endocrinological and roentgenological studies suggested left adrenal cortical cancer. Left adrenalectomy with para-aortic lymph node dissection was performed on October 19, 1977. The tumor was removed together with left kidney. It measured 12.5×18.0×7.5cm and weighed 1, 190g. Postoperatively the patient improved temporarily. Metastases to lung and liver, however, developed and he died four months after the operation. Electron microscopic examination of the tumor revealed poorly developed smooth surfaced endoplasmic reticuli and decreased number of mitochondria with sparse short tubular cristae. This finding is different from that of cells in normal fascicular and reticular zones which have abundant smooth and rough surfaced reticuli and mitochondria with vesicular cristae. It was suggested that each tumor cell had less steroid producing ability compared with normal adrenocortical cell, although the whole tumor was producing a large amount of steroids. Slow production of steroids in the tumor might have delayed the diagnosis of the disease, while the tumor itself had already grown up to invade the adjoining organs. The authors assume that the activity to produce steroids in the tumor is not paralleled with its growing or invading activity.View full abstractDownload PDF (2078K)
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