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Volume 47, Issue 3
Displaying 1-3 of 3 articles from this issue
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2. ON THE DISTRIBUTION OF NUCLEIC ACID WITHIN THE KIDNEY PARENCHYMAHiroshi Takahashi1956 Volume 47 Issue 3 Pages 143-150
Published: 1956
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSThe author studied on the kidney parenchyma, especially on the nucleic acid within it, by means of the histochemical method and obtained the following results.
1. In the relative fresh caseous focus of tuberculous kidney, many fragments of nucleus, which are constituted with high molecular DNA, exist separately in the state of granule and the focus simultaneously contains a few DNA of low-molecule.
2. The increase of DNA in the tuberculous tissue of kidney depends upon the nuclei of Langhans's giant cells, epitheloid cells, lymphocytes, plasma cells and fibroblasten, based on the tuberculous changes of tissue, and also upon the DNA within caseous focus itself.
3. Desoxy-ribo-nucleic-acid-cylindroids of which Feulgen's reactions were strong or weak positive were recognized in the ratio of about 20% of the total of tuberculous kidney. These cylindroids, in the fresh case, reveal the nuclei of destructed cells but, in later, disclose the reduction of quantity of nucleic acid and the homogeneous weak-positive reaction which has lost the specific stainability of nucleus.View full abstractDownload PDF (5891K) -
II. REPORT; RENAL EXTRACTION RATIO OF SODIUM PARA-AMINO HIPPURATE AND SODIUM THIOSULFATEHiroshi Kobayashi1956 Volume 47 Issue 3 Pages 151-164
Published: 1956
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSIn 75 kidneys of 53 patients with urological renal diseases, renal function was evaluated by measuring renal extraction ratio of PAH (EPAH) and STS (ESTS) by means of renal vein catheterization.
The results were as follows:
1) The mean of EPAH and ESTS of 20 normal kidneys was 88. 86±2. 99% and 25.21±4.08% respectively, which revealed nearly constant normal EPAH (82.3 to 94.6%, whereas widely ranged normal ESTS (19.4 to 33.8%)
2) The average of EPAH and ESTS of eight normal right kidneys was 90.7±2.4% and 24.6±3.94% respectively, that of 12 normal left kidneys being 87.6±3.7% and 25.6±4.2%, and thus revealing no statistically significant differences between right and left side. Sufficiently deep left renal vein catheterization was proved to enable to measure a reliable extraction ratio.
3) The average of EPAH and ESTS in pathological cases was as follows: In the first degree of damage of renal function, EPAH 76.9±9.59%, ESTS 18.6±5.3%: In the second degree of damage of renal function, EPAH 62.9±22.8%, ESTS 18.4±6.6%: In the third degree of damage of renal function, EPAH 13.9±12.4%, ESTS 10.8±6.9%. Contrast medium is not visible on intravenous pyelogram in cases where EPAH and ESTS are lower than 30% and 10% respectively. Accordingly this measurement of extraction ratio is most suitable in cases where intravenous pyelogram fails to show any excretion of contrast medium.
4) The measurement of the extraction ratio enables not only to show the degree of impairment of renal function, but also to establish a plan of treatment.
5) This method is also able to disclose the function of anuric kidney.
6) This is one of the most useful clinical tests which can demonstrate the separate renal function exactly.View full abstractDownload PDF (5259K) -
Seizo Horiuchi1956 Volume 47 Issue 3 Pages 165-195
Published: 1956
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSDownload PDF (9135K)
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