To clarify the appropriate therapy on the neurogenic bladder, the innervation and the pathological physiology of the urinary bladder received various injuries on its nervous system was studied, and many works presented from our clinic. On the other hand, it is well known that the pudendal nerve had very important role in the mechanism of micturition, while the blocking of this nerve is recognized as one of the available therapy against the neurogenic bladder.
Here, the histological studies on the innervation of the pudendal nerve, especially the dorsal nerve of penis, on the urethra and the penis, and the origin of that nerve in the spinal cord were performed with the observation of degenerated nerve fibers following the section of various spinal nerves, and the results described below were obtained.
1) In the adult male dog, the pudendal nerve occures in the form of one bundle from the pudendal plexus, and this bundle branches away the dorsal nerve of penis. This nerve branches again into the ramus penis and the rami urethrae posterior, the former extends to the top of the penis along the dorsal part of the penis, while the latter spreads to the somewhat upper part of the prostate along the ventral part of the posterior urethra. These facts reveal the innervation of the pudendal nerve to the posterior part of the urethra.
2) The composition of the myelinated nerve fibers in the pudendal nerve and the dorsal nerve of penis was examined in 20 cases adult male dog. The average number of the total myelinated nerve fibers was 3484 in the main trunk of the pudendal nerve, 1556 in the ramus penis of the dorsal nerve of penis, 405 in the proximal part of the rami urethrae posterior, and 172 in the peripheral part of this rami. While, any of these were composed of the small-sized nerve fibers in 71.5-74.5%, medium-sized in 22.2-24.4%, large-sized fibers in 2.4-4.5%, and maximum-sized fibers in 0.6-1.0%, respectively, and it was remarkable that the innervation of the small-sized nerve fibers was significantly dominant comparing to that of other fibers.
3) After the section of main trunk of the pudendal nerve, 88.1-95.5% of the nerve fibers in the ramus penis and 88.1-96.3% of that in the rami urethrae posterior were degenerated, while 0.1-0.3% of the nerve fibers only in the ramus penis were degenerated after the section of the pelvic or the hypogastric nerve. With these results it was assumed that the most part of the penis and the posterior urethra was innervated by the pudendal nerve, and only a part of the ramus penis was contributed by the pelvic and the hypogastric nerves.
4) With the observation on the degenerated fibers, 86.9-88.9% of the nerve fibers in the ramus penis and 47.5-56.7% in the rami urethrae posterior were originated from the dorsal root of the S_1-3 spinal nerves and corresponded to the pudendal nerve or the dorsal nerve of penis; while, 6.8-8.8% in the ramus penis and 23.3-31.7% in the rami urethrae posterior was originated from the ventral root of the same spinal nerves, respectively. Therefore, it was clarified that the innervation of S_1-3 dorsal root was dominant in the pudendal nerve and the dorsal nerve of penis, especially in the ramus penis; while the innervation of S_1-3 ventral root was significant in the rami urethrae posterior and poor in the ramus penis. And furthermore, the most significant correspondence of innervation of the spinal nerve against the pudendal nerve or the dorsal nerve of penis was found in the 2nd sacral nerve concerning to both the ventral and the dorsal root nerve fibers, and this was followed by the 1st and then 3rd sacral nerves.
5) The centrifugal nerve fibers of the dorsal root in the pudendal nerve and the dorsal nerve of penis was examined by the section of the dorsal root of the spinal nerve, and the degenerated nerve fibers in 4.8-8.2% of the myelinated fibers of these nerves. This results show the existence of the centrifu

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The perineal biopsy for the prostate with the Vim Silverman needle was performed 243 times, during May of 1959 to January of 1963, on 217 cases which were diagnosed by the palpation as the prostatic cancer (40 cases), doubted on the prostatic cancer (34 cases), diagnosed as the prostatic hypertrophy (107 cases), and the prostatitis (36 cases), respectively.
In comparison of the results on the detection of the prostatic cancer by the palpation or the perineal needle biopsy, the cancer was detected by the biopsy in the rate of 71% among the cases which were diagnosed as the cancer by the palpation, while 11.5% of the cases which were doubted on the cancer by the palpation was confirmed as the cancer in the same manner.
Furthermore, 59% of 107 cases which were diagnosed as the hypertrophy by the palpation, was also revealed the same findings, however, the cancer was discovered in the rate of 11.3% of them by the perineal biopsy. While, 77.2% of 36 cases which were diagnosed as the inflammation by the palpation, has showed the same results by the biopsy, but 11.4% of them revealed the cancerous sign by the same way.
The accuracy rate of the diagnosis by the perineal biopsy was examined by the comparison of the histological findings of the specimens which were prepared by the operation of the prostate.
The cancer was proved significantly in the rate of 93.7% of the cases which were diagnosed as the same by the biopsy, while only 2 of 5 cases, which were doubted on the cancer by the biopsy, was confirmd as the cancer.
The latent carcinoma was recognized in 2 of 3 cases which were diagnosed as the same by the biopsy but on the another one case only the findings of the hypertrophy was noticed.
The hypertrophy was confirmed on 41 of 45 cases (91.10), which were diagnosed as the same by the biopsy, however, 2 cases of the latent carcinoma and 2 cases of the inflammation were found by the histological examination of the extirpated prostate through out the operation.

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1) A case report of spontaneous rupture of the malignant tumor of the right kidney in a child is presented. The patient is a girl aged 2 years and 2 months, who had haematuria, fever and a state of shock. Nephrectomy was performed. The size of the removed kidney was 9×6×6cm, and the weight was 105g. Pathological diagnosis was renal cell carcinoma (of embryonal type).
2) Malignant kidney tumor in children is very rare except Wilms's tumor. 36 cases (containing our case) of renal cell carcinoma in children under 15 years old in Japan until 1962 are collected, tabulated and reviewed.
3) Spontaneous rupture of a kidney is uncommon and especially it is extremely rare in a kidney tumor. 36 cases (containing our case) of spontaneous rupture of kidney tumor in Japan, Europe and America, are tabulated.
4) In Japan there have been only 3 cases (containing our case) of spontaneous rupture of kidney tumors, and two of them are children's cases.

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