The Japanese Journal of Urology
Online ISSN : 1884-7110
Print ISSN : 0021-5287
Volume 75, Issue 10
Displaying 1-18 of 18 articles from this issue
  • Haruo Ito, Mitsusuke Murakami, Taisei Miyauchi, Hitoshi Naito, Ikuo Mo ...
    1984 Volume 75 Issue 10 Pages 1523-1527
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    We studied whether coagulum renal stone surgery reduces residual stones and true recurrence. Diagnosis of the recurrence was given only to those confirmed by KUB and IVP.
    As to single stone, no residual stone was found in any of 56 cases of pyelolithotomy, 10 cases of coagulum pyelolithotomy and 2 cases of nephrolithotomy. In the cases of multiple stones, residual stones were found in 11 of 26 cases of pyelolithotomy (42%), 9 of 34 cases of coagulum pyelolithotomy (27%). Stones were retained in 3 of 10 cases (30%) of nephrolithotomy and 5 of 16 cases (31%) of coagulum nephrolithotomy performed to remove staghorn stones.
    Recurrences were observed in 9 out of 44 cases (20%) which underwent pyelolithotomy (average observation period-20 months) and 3 out of 28 cases (12%) of coagulum pyelolithotomy (average observation period-23 months).
    True recurrences were noted in 2 out of 9 cases (22%) of nephrolithotomy (average observation period-13 months) and in 2 out of 10 cases of coagulum nephrolithotomy (20%, average observation period-23 months). As to urinary infection or stone composition, there was no difference between the cases in which coagulum was used and those in which it was not used.
    Considering that coagulum was employed both in pyelolithotomy and nephrolithotomy for the cases of complex stones, it is concluded that residual stones and true recurrence were reduced by the use of coagulum.
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  • Shigeyuki Kotera
    1984 Volume 75 Issue 10 Pages 1528-1540
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Electron microscopic observations of the peritubular wall of the seminiferous tubules were made in 18 cases of human cryptorchidism. The peritubular wall was composed of two main layers: the basement membrane and the tunica propria. The basement membrane was composed of the lamina lucida, the lamina densa, and the zona reticularis; the tunica propria was composed of the non-cellular layer and the cellular layer.
    The pathological changes observed in cryptorchids were infolding, irregularity, obscurity, lamellation, pleating, and thickening in the basement membrane, and thickening due to the progressive fibrosis of collagen in the tunica propria. Infolding was seen in subjects aged 3 years or older, irregularity in those aged 4 years or older, obscurity in those aged 3 years or older, and lamellation and pleating in those aged 17 years or older. The thickness of the basement membrane in a 2-year-old subject was 1.5 times that in a healthy boy. The thickening increased with age, so that in adult subjects, the thickness was approximately two to four times that in a normal adult.
    These changes in the basement membrane reflect dysfunction of the Sertoli cells, which make up the basement membrane. Pathological changes were observed in cryptorchids as young as 2 years of age.
    The thickening of the tunica propria in a subject with infantile cryptorchidism was 1.3-1.5 times that in a normal boy. In adult subjects, it was 5 times that in a healthy adult. These changes in the tunica propria were due to progressive collagen fibrosis.
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  • Hideaki Saeki
    1984 Volume 75 Issue 10 Pages 1541-1550
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Ureteral transport of urine is dependent on the ureteral peristaltic rate and the bolus volume.
    The present investigation revealed that ureters in dogs responded to increasing urine flow in one of the following five peristaltic patterns demonstrating the interdependence of rate and bolus volume.
    A: an increase in the rate and a decrease in the bolus volume
    B: an increase in the rate and no change in the bolus volume
    C: an increase in the rate and an increase in the bolus volume
    D: no change in the rate and an increase in the bolus volume
    E: a decrease in the rate and an increase in the bolus volume
    In a gradual increase in urine flow; mostly the rate and the bolus volume of ureteral peristalsis increased, but occasionally the rate or the bolus volume decreased with a compensatory increase of the other.
    In a rapid increase in urine flow by administration of Furosemide; at urine flow lower than 1.0ml/min, a rapid increase of the rate and no change or a decrease of the bolus volume occurred immediately after administration of Furosemide, but in a short time a rapid increase of the bolus volume followed. At urine flow higher than 1.0ml/min, the rate marked a maximun and did not increase further, but the bolus volume increased rapidly.
    The urine flow at the begining of a column of urine and the maximun bolus volume are both larger in cases of gradually increasing urine flow than in cases of rapidly increasing urine flow.
    The rate of ureteral peristalsis at high urine flow was several times more than at low urine flow. On the other hand, the bolus volume at high urine flow was one hundred times more than at low urine flow. This may suggest that the bolus volume plays an more important role in ureteral transport of increasing urine.
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  • Teiichi Motoyama, Takahiko Yamamoto, Shohtaroh Satoh, Osamu Sugita
    1984 Volume 75 Issue 10 Pages 1551-1557
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Several characteristics of alkaline phosphatases (ALP) in cultured embryonal carcinoma cells were studied by cytohistochemical and biochemical methods. The cell lines, ITO and NEC8, were derived from human testicular germ cell tumors.
    A few ALP-positive cells were found in the ITO cell line. Electronmicroscopically, small cells of yolk sac tumor type were positive for ALP. The activity was less heat-stable and more sensitive to L-homoarginine than the late placental ALP, with a marked sensitivity to L-leucine. It was difficult to identify the activity with the well-known isoenzymes in the ITO line.
    Many ALP-positive cells were seen in the NEC8 cell line. The free-surface with microvilli of adult type embryonal carcinoma cells showed the most strong activity. The activity was heat-labile and markedly sensitive to L-homoarginine. The cell extract produced electrophoretically a band compatible to ALP3. These characteristics of the activity were similar to the early placental isoenzyme. The late placental isoenzyme was not detected in both the cell lines.
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  • A Study by Immunohistochemistry and Radioimmunoassay
    Mototsugu Kanokogi
    1984 Volume 75 Issue 10 Pages 1558-1571
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    In order to evaluate the diagnostic and prognostic significance of carcinoembryonic antigen (CEA), an immunohistochemical study, using the peroxidase-antiperoxidase (PAP) method, of localization of CEA on tissue sections in one hundred and forty-six cases with primary tumors of the bladder, ureter, and renal pelvis was performed. In addition, in some of the cases, CEA values in serum, urine, and tumor tissue extract were also examined by radioimmunoassay.
    The following results were obtained:
    1) Immunohistochemically, CEA-positive tumor cells were found in 63 of 127 transitional cell carcinomas (TCC), 3 of 4 adenocarcinomas, and all of 5 squamous cell carcinomas, but not in any other malignant nor benign tumors.
    2) Concerning the primary sites of the tumors, there was no significant difference in the incidence and distribution of CEA-positive tumor cells among TCC of bladder, ureter, and renal pelvis.
    3) In TCC, CEA-positivity in the tumor cells correlated significantly to the histological grade (p<0.005), pathological stage (p<0.005), and occurrence of local recurrence (p<0.025). Therefore, CEA-positivity in the tumor cells seems to be a parameter for the malignant potentiality of the tumor.
    4) In TCC of the bladder, there was no significant correlation between CEA-positivity in the tumor cells and values of serum and/or urinary CEA, showing that these three parameters are independent of each other.
    5) In TCC of the bladder, although both values of serum and urinary CEA were not satisfactory as diagnostic information, the former was elevated significantly in cases with distant metastasis (p<0.05), and the latter in high stage cases with muscular invasion (p<0.05).
    6) CEA was thought to be a more specific tumor marker in urachal carcinoma than in TCC because of its high concentration in the serum and tumor tissue extract. On the other hand, in mesonephric adenocarcinoma it was not detected immunohistochemically. These findings suggest embryologically different pathogeneses of the two adenocarcinomas.
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  • The Role of the Pudendal Nerve on the Dynamics of Micturition in the Decerebrated Dog
    Sadamoto Satoh
    1984 Volume 75 Issue 10 Pages 1572-1582
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    The present study was designed to clarify the role of the pudendal nerve in the dynamics of micturition in the dog. The voiding cycle was studied by measuring the bladder pressure, urinary flow, sphincter EMG, before and after pudendal nerve transection in 16 decebrated dogs.
    The bladder pressure was monitored via a catheter inserted into the bladder, which was connected to a pressure transducer. The urine flow was measured by an electromagnetic flowmeter attached to the external urethral meatus. The EMG of the sphincter was recorded by a needle electrode.
    In the control conditions, highly reproducible reflex micturition was demonstrated. Bladder contraction and spasmodic contraction of the sphincter play an important role in bladder emptying, however bladder emptying is incomplete generally. The patterns of micturition after pudenal nerve transection were divided into three groups as follows. In 9 out of the 16 dogs, reflex micturition was developed after bilateral pudendal nerve transection. In 5 out of the 16 dogs, overflow incontinence was revealed after bilateral pudendal nerve transection. In 2 out of the 16 dogs overflow incontinence was present after unilateral pudendal nerve trasection. Furthermore, after pudendal nerve trasection, the spasmodic contraction of the sphincter was diminished to decrease the efficacy of the bladder emptying.
    It appears that pudendal nerve induces the spasmodic contraction of the sphincter which is neccessary for bladder emptying in decerebrated dogs.
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  • Regenerative Hyperplasia of Rat Urinary Bladder Urothelium after Transurethral Fulgulation
    Hideyuki Akaza, Kiyoo Koseki, Nobuo Moriyama, Toru Suzuki, Tadao Niiji ...
    1984 Volume 75 Issue 10 Pages 1583-1587
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Urothelial regeneration after various mechanical or chemical injuries was studied histologically in relation to the genesis of bladder cancer. In this study transurethral cauterization was performed on female Sprague-Dawley rats to cause a fulgurated ulcer on the bladder mucosa. By light microscopy, the acute changes at the fulguration sites showed bleeding ulcerated lesions followed by infiltration of inflammatory cells. Nodular or papillary regenerative hyperplasia of the urothelium was observed in later stages. By scanning electron microscopy, regenerative urothelial cells with short microvilli on the luminal surface were observed. The regenerative hyperplasia was most prominent on Days 7 and 14, after the cauterization, and disappeared by Day 28. In conclusion, a reversible, regenerative hyperplasia of the rat urothelium was induced by transurethral fulguration.
    This regenerative change may be useful as a model of bladder carcinogenesis.
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  • Koji Hiraishi, Masataka Yonezawa, Shoichiro Nakamura, Shuzo Yamamoto, ...
    1984 Volume 75 Issue 10 Pages 1588-1594
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    We have experienced 24 cases of childhood urolithiasis during 19 years at Tokushima University Hospital. The frequency of childhood urolithiasis ranged from 0 to 3 cases per year, comprising 1.2% of 2080 urolithiatic patients of all ages during the same period. Of the 24 patients, 21 (87.5%) had upper urinary tract stones and 3 had vesical calculi. There were 18 boys and 6 girls with a sex ratio of 3:1. There was no patient under the age of 4 years and 14 patients were between 12-15 years old. The chief complaints were abnormal urine in 9 patients and asymptomatic gross hematuria in 3 patients. Urinary tract infection was found in 12 (50%) patients and proteus species was the predominant bacteria. Factors predisposing stone formation were found in 16 (66.7%) patients. They were metabolic disorders in 9 (37.5%), urinary tract malformation in 4, controlled leukemia in 1 and foreign bodies in 2 patients. The remaining patients included 3 with idiopathic lithiasis and 5 with insufficient metabolic work-up. Seventeen operative procedures including mainly each four of nephrolithotomies, pyelolithotomies and ureterolithotomies were performed on 15 patients, of whom two demonstrated residual stones. Nephrectomy was not done in any case. Stone recurrence was observed in 3 out of 14 patients at more than 1 year after initial therapy (average 63 months). The most common stone component was calcium oxalate.
    Compared with other Japanese reports on childhood urolithiasis, three characteristic findings appear to be notable. First, the age incidence was higher in our series and no patient was under 4 years old. Second, metabolic disorders were most frequently found to be the cause of stone formation. Third, no nephrectomy was experienced.
    When reviewing the European and American literatures on childhood urolithiasis, the epidemiologic difference can be observed in these two regions and we discussed about it.
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  • THE 1ST REPORT
    Kaoru Saito, Hiromi Kato, Yoshinori Komeda
    1984 Volume 75 Issue 10 Pages 1595-1601
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    N-acetyl-β-D-glucosaminidase (NAG) activities in the urine of patients with urinary tract disorders were assayed by a photometric method using NAG test (Shionogi) and a UVIDEC-60 spectrophotometer.
    1) NAG activity in the urine showed a diurnal variation with a peak in 6 to 9a.m.
    2) The mean urinary NAG activity was 6.0±4.6U/L. There was no significant difference between the sex. Aged patients showed a higher NAG level.
    3) Urinary NAG activity was highest in patients with renal insufficiency, and higher with malignant diseases and lower urinary tract obstruction such as benign prostatic hypertrophy.
    4) Urinary NAG excretion was significantly higher in patients with abnormal urinary β2-microglobulin level and low creatinine clearance than in normal subjects.
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  • Evaluation of Renal Function by 99mTc-DMSA Renal Scintigraphy
    Ryuichiro Konda, Seiichi Orikasa, Goro Nakamichi
    1984 Volume 75 Issue 10 Pages 1602-1610
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    The function of 78 kidneys of 52 pediatric patients with VUR was evaluated by 99mTc-DMSA renal scintigraphy.
    A low DMSA renal uptake rate was frequently found out in those with high grade reflux or with abnormalities on IVP, but these findings did not always conincide with the grade of VUR or with the IVP findings. Serious renal dysfunction was noted in 14% of those with low grade VUR and in in 11% of those with normal IVP.
    DMSA renal uptake rate in small kidneys below 2SD of renal ratio ranged from 1.7% up to 21.4% with a mean of 14.3%. It is likely that there was serious renal dysfunction in small kidneys.
    Those with β2-MG urinary ratio as high as over 1.0 tended to show a low DMSA uptake rate, but there was no correlation identified between the two parameters. These results indicated that parameters such as DMSA renal uptake rate, renal ratio and β2-MG urinary ratio reflect the timing of varying renal dysfunction.
    The comparison of renal scintigram with IVP revealed an abnormal renal scintigram in 40% of those with normal IVP and in 76% of those with abnormal IVP. The findings on the renal scintigram and those on IVP did not always conincide with each other, and it was realized that a substantial number of cases with normal IVP were accompanied by nephro-cortical disturbances.
    It was thus found out that neither grade of reflux nor findings on IVP could serve as criteria for assessing renal dysfunction by reflux and that the limit for conservative therapy was thought to be about 1.0 in β2-MG urinary ratio and about 20% in DMSA renal uptake rate. Furthermore, small kidneys were accompanied by serious renal dysfunction, and it is recommended to take adequate measures such as antireflux operation before development of a small kidney.
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  • I. Relationship between Donor Factors or Ischemic Time of the Graft and Reversibility of the Function
    Hideari Ihara, Masaaki Arima, Fumihiko Ikoma, Yasuji Ichikawa, Michio ...
    1984 Volume 75 Issue 10 Pages 1611-1618
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    With the purpose of predicting the reversibility of cadaveric renal allograft function, relationship between donor factors, such as age, sex, cause of death, donor source or ischemic time of the graft and reversibility of the function were studied in 20 cadaveric renal trasplant recipients.
    Although the onset of diuresis was significantly delayed in the grafts from donors who died of cerebral hemorrhage, no significant correlation was observed between the causes of death and the reversibility of the graft function after onset of diuresis. There were no significant correlations between the age, sex of donor, donor source or ischemic time of the graft and the reversibility of the function.
    After the onset of diuresis, significant correlations were observed between the parameters of graft function recovery, such as increment of urine volume (ΔUV), increment of creatinine clearance (ΔCcr) or decrement of serum creatinine (ΔS-Cr) and the short-term prognosis.
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  • II. Prediction of Function Reversibility with Monitoring of Hemodynamics of the Grafts by Ultrasound Doppler Technique
    Hideari Ihara, Masaaki Arima, Fumihiko Ikoma, Yasuji Ichikawa, Michio ...
    1984 Volume 75 Issue 10 Pages 1619-1630
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Measurements of arterial blood flow of the transplanted kidneys by directional ultrasound Doppler technique were performed in 20 cadaveric renal transplant recipients with the purpose of predicting the reversibility of cadaveric renal allograft function and diagnosing acute rejection during posttransplant anuric phase.
    Reversibility of the graft function was predictable by blood flow pattern analysis even within a week after transplantation. Serial measurements of the blood flow made it more predictable. Of blood flow parameters, acceleration time had a good correlation with the reversibility of the graft function.
    Acute rejection episodes in posttransplant anuric patients were able to be diagnosed by this method, demonstrating mainly diminished diastolic blood flow in Doppler flow pattern.
    This method appears to be a useful technique for management of cadaveric renal transplant recipients, especially those with posttransplant anuria.
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  • Hiromitsu Noto, Tadashi Harada, Kimio Sugaya, Takashi Morita, Osamu Ni ...
    1984 Volume 75 Issue 10 Pages 1631-1636
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    A new modified catheter for recording of the electromyogram of the external urethral sphincter through a needle electrode is described. This catheter is a 20 Fr. urethral balloon catheter and has 4 channels, which are for the measuring of bladder and urethral pressure, for infusion of the bladder and for the recording of the electromyogram. The needle electrode is monopolar and 0.2mm in diameter. The channel for electromyography is set to remain in contact with the external urethral sphincter when the balloon is inflated near the bladder neck. Therefore, by inserting the electrode into the channel, we can record the electrical activity of the external urethral sphincter easily and exactly.
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  • Significance of Nuclear Morphologic Grade in Prognosis
    Shoichiro Nakanishi, Akira Kashiwagi, Shigeo Sakashita, Akio Maru, Tom ...
    1984 Volume 75 Issue 10 Pages 1637-1645
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    A clinico-pathological study was performed in 154 patients with renal cell carcinoma experienced during the 14-year-period from 1969-1982.
    The prognosis was correlated with the clinical stage based on Robson's classification and in particular with pathological features such as cell type, structural pattern and nuclear morphologic grade (NMG) as well. By modifying Skinner's grading system, NMG was divided into four subgroups (grade 1 to 4) depending on the differences in nuclear size, oral shape, irregularity, chromatin pattern and nucleoli prominence.
    Results:
    1) The 5-year survival rates were 68.0%, 64.9%, 34.9% and 6.2% for stages I, II, III and IV, respectively. The survival rates and stages were significantly correlated as a whole but the difference between stage I and II was not statistically significant.
    2) Neither cell type nor structural pattern has no relevance to survival, while mixture of spindle cell and sarcomatoid pattern was definitely a poor prognostic sign.
    3) The 5-year survival rates were 80.4%, 71.5%, 33.1% and 7.9% for grades 1, 2, 3 and 4, respectively. As with the stages, there was a significant correlation between the survival rates and grade, although simplified classification by high grade (3 and 4) and low (grade 1 and 2) system is also indicative of poor and favorable prognosis, respectively.
    4) Stages and grades were correlated well in such a way that lower stage tumors were comprised mainly of lower grade ones and vice versa. Although both are of prognostic value in assessing the patients as a group, grades were more indicative of individual prognosis, since death with low stage tumors was found only in patients with high grade tumors and most long term survivors with high stage tumor demonstrated low grade tumor.
    5) MNG was more valuable than the other pathological findings in predicting the subsequent course of patints following nephrectomy, when combined with clinical stage.
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  • Yoji Katsuoka, Toshifumi Kawashima, Miki Shiramizu, Yasuhide Murakami
    1984 Volume 75 Issue 10 Pages 1646-1651
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Approximately one third of patients discovered to have renal cell carcinoma already have distant metastasis at the time of tumor diagnosis. The commonest sites for metastasis are lungs, lymphnodes, and bones. Adrenal metastasis is a fairly common finding in autopsy series with a 7 to 19 per cent incidence reported. Nonetheless, the diagnosis of the metastasis to the adrenal is uncommon during life. In the literature, ipsilateral adrenal involvement has been previously reported to occur in 5.7% of all patients undergoing radical nephrectomy for renal cell carcinoma. In contrast, it seems suprising that metastatic renal cell carcinoma in the contralateral adrenal gland is not found more frequently. A case of a contralateral adrenal metastasis is here presented, and the literature is reviewed.
    A 77-year-old man was admitted to a local hospital on October 1977, with urinary retention and gross hematuria. The patient was referred to our department, where extensive roentogenographic studies were performed. Results of arteriography and vena cavography demonstrated a large hypervascular mass in the upper pole of the kidney and tumor thrombus in the renal vein and vena cava consistent with a renal cell carcinoma. The patient underwent transcather embolization because of massive bleeding, thereafter a right radical nephrectomy an adrenalectomy including inferior vena cava wall resection. One year after discharge a CT scan disclosed a left suprarenal mass in the contralateral adrenal, suggestive of metastatic renal cell carcinoma. A left adrenalectomy was performed for treatment of the solitary metastatic lesion. Histologically, the tumor of the left adrenal was identical to the right renal cell carcinoma. The patient required adrenal cortical steroid (Hydrocortisone) and remained well over a two year follow-up interval.
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  • A REPORT OF 3 CASES
    Hiroaki Masuda, Kazuhiko Fujii, Masahiro Hata, Nobutaka Ohta, Kazuo Su ...
    1984 Volume 75 Issue 10 Pages 1652-1657
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Three cases of renal artery aneurysm are presented.
    One of the 3 cases showed a renal artery aneurysm in a congenital solitary kidney. All the cases were successfully treated by ex vivo surgery (renal artery aneurysmectomy) and renal autotransplantation. The case of renal artery aneurysm in congenital solitary kidney resulted in acute renal failure postoperatively and required hemodialysis 9 times for 3 weeks. Thereafter, the renal function recovered completely. Excellent results were obtained also in the other 2 cases.
    168 cases of renal artery aneurysm including our 3 cases have been reported in the Japanese literatures. Among those cases, renal artery aneurysm in congenital solitary kidney was noted only in 8 cases including the case reported here. As for the treatment, most of the reported cases were treated by in situ excision of the aneurysm or nephrectomy. There have been only 7 cases including the 3 cases of the our present series. We believe that the ex vivo surgery for renal artery aneurysm is not only useful for preservation of the postoperative renal function but also a safe and excellent procedure to remove the aneurysm situated in distal small branches of the renal artery.
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  • REPORT OF TWO CASES
    Seigo Hiraga, Yutaka Uchijima, Junji Kurokawa, Yujin Koyama, Kazunori ...
    1984 Volume 75 Issue 10 Pages 1658-1664
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Case 1: an 8-year-old girl was admitted with chief complaints of recurrent acute pyelonephritis and enuresis to have diagnosed as distal urethral stenosis after clinical examinations including urodynamic study. Transurethral resection of the bladder neck and urethral dilation were carried out. Case 2: a 9 year-old-boy was admitted with chief complaints of turbid urine and intermittent fever attack to have diagnosed as so-called megacystis syndrome proposed by Paquin et al. after various examinations including urodynamic study. Bilateral nephrostomy was performed in this case.
    Both of these cases were found to have severe vesicoureteral reflux and marked hydronephrosis despite the different clinical diagnoses. Urodynamic studies demonstrated an abnormally high intraurethral pressure and the pathophysiology that there was no detrusor-sphincter dyssynergia with a functional urethral obstruction. These findings were interesting in relations to the pathogenesis of congenital passage-disturbance of the lower urinary tract and the importance of urodynamic studies about the lower urinary tract for pediatric dilated ureters was stressed.
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  • Shuhei Onishi, Kazuhiko Nishimoto, Haruhiko Ueda, Haruo Noda, Shigeki ...
    1984 Volume 75 Issue 10 Pages 1665-1669
    Published: October 20, 1984
    Released on J-STAGE: July 23, 2010
    JOURNAL FREE ACCESS
    Except metastatic lesions, germ cell tumor is rarely found outside genital glands.
    A 26-years-old male presented with right lower abdominal dull pain. Physical examination revealed a right lower abdominal tumor and a mass in the left supraclavicular fossa. A needle biopsy of the supraclavicular mass showed embryonal carcinoma with choriocarcinoma. However, there was no malignant finding including burned-out testicular tumor in serial sections of the bilateral testes. Based on pyelography, CT scan and angiography, it was suggested that the germ cell tumor had primarily developed in the retroperitoneal region.
    Concept and treatment of the extragonadal germ cell tumor are discussed.
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