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Volume 64, Issue 10
Displaying 1-7 of 7 articles from this issue
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Experimental Studies on Radioisotope PenogramMasafumi Shirai1973 Volume 64 Issue 10 Pages 779-785
Published: October 20, 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSIn order to establish various conditions for radioisotope penogram, basic experiments were carried out using adult dogs. When 181I-human serum albumin is used as the isotope, a dose of 10μCi/dog in dogs of 10-15 kg body weight appears to be adequate. A collimator specifically designed for this test also seems to be necessary. Regarding the relationship between radioisotope penogram and peripheral nerves, stimulation of pelvic nerves resulted in a marked rise in the penogram curve but stimulation of the central stump after section of this nerve caused no such effect. When erection nerves are organically injured in man, even intense stimulation from the erection center does not cause a rise in the penogram curve, in agreement with this observation. Experimental proof for the usefulness of radioisotope penogram in differentiating between organic and functional impotences was thus provided.View full abstractDownload PDF (3395K) -
Differential Diagnosis between Functional and Organic Impotences by Radioisotope Penogram upon Loading with Visual Sexual StimulationMasafumi Shirai1973 Volume 64 Issue 10 Pages 786-792
Published: October 20, 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSAs the method for objective differentiation between functional and organic impotences, radioisotope penogram with measurement of changes of blood flow through the penis using radioisotope was developed and applied. In the present study, changes of the radioisotope penogram curve were studied upon visual sexual stimulation. In patients with functional impotence, penogram curve rose in response to visual sexual stimulation while in cases with organic disturbance in the nervous system participating in erection including the upper center, penogram curve failed to react entirely despite sexual excitation in response to visual sexual stimulation, making differential diagnosis possible.View full abstractDownload PDF (3157K) -
Takao Osada, Takeo Inoue, Akihiko Hirano1973 Volume 64 Issue 10 Pages 793-801
Published: October 20, 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSIn order to investigate the local immune defense mechanism of urinary tract disease, secretory IgA, which seemed to participate these local defense system, was measured in the urine of patient with lower urinary tract disease. Urinary IgA, IgE, IgG and IgM were estimated simultanously. The single radial immunodiffusion was used for all of the measurement.
The study was done in the patients with acute cystitis, chronic cystitis, acute pyelonephritis, non-infected urinary tract disease and normal adult.
1) Urinary secretory IgA levels showed a high value in most patients with cystitis, both acute and chronic form, but not in acute pyelonephritis.
2) In all of patients with non-infected urinary tract disease, urinary secretory IgA levels were below normal.
3) Urinary secretory IgA levels, in patients with urinary tract tumor, did not show a high value.
4) Furthermore, in urinary IgA, IgE, IgG and IgM, there was no statistical difference among each group, except IgG which was increased in some cases of urinary tract infection, especially chronic cystitis.
From these findings, we suggest that urinary secretory IgA level reflects the antibody response of the lower urinary tract infection.View full abstractDownload PDF (2804K) -
Hideo Hidai, Hiroshi Fukuoka, Tetsuo Murayama, Takeshi Takeda, Katsuak ...1973 Volume 64 Issue 10 Pages 802-807
Published: October 20, 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSTwo cases of bilaterally nephrectomized patients were studied hematologically for serum erythropoiesis stimulating factor (ESF), Hct. value, Hgb. content, reticulocyte count and monthly transfused blood volume, before, during and after administration of testosterone 100-400mg/wk for 7 months. The patients were also investigated on serum ESF in renal, hepatic and peripheral vein blood which were drawn selectively before bilateral nephrectomy.
No ESF was detected in renal, hepatic and peripheral vein blood, drawn preoperatively. Serum ESF was neither found postoperatively nor during androgen administration. No remarkable improvement of their anemia was noted clinically on androgen administration.
Four cases of regularly dialyzed patients were studied in similar way as control. The control group did not show any significant change in their state of anemia after androgen administration as in anephric group.View full abstractDownload PDF (650K) -
Relationship between Structure and Differentiation of Cancer CellsYusuke Fuse, Junichiro Fujieda, Hiroshi Ohmuro, Michito Katsume1973 Volume 64 Issue 10 Pages 808-828
Published: October 20, 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSBiopsied tumor tissues of 23 cases of human bladder carcinomas were histologically and electron-microscopically investigated. The majority of well-differentiated papillary transitional cell carcinomas (Grade I and II) revealed the surface tumor cells accompanied by large granule, degenerative vacuoles and pseudoadenomatous lumina in their surfaces. The well-differentiated cancer cells showed electron-microscopically the various cytoplasmic organelles such as mitochodria, tight junction, desmosomes, endoplasmic reticulum Golgi apparatus and lysosomes.
On the other hand, squamous and glandular metaplastic foci, disappearance of surface tumor cells and an increase of dark cells and exfoliation of tumor cells were observed in poor-differentiated cancers (Grade III and IV). The poor-differentiated cancer cells showed eletron-microscopically a decrease of various cytoplasmic organelles, especially tight junction, desmosome and mitochondria, and an increase of free ribosomes and microvillous cytoplasmic protrusions and intercellular spaces.
The quantity of glycogen and cytoplasmic fibrile of tumor cells were seemed not to be proportional to differentiation of cancer. In the squamous metaplastic foci in bladder cancers were electron-microscopically observed an increase of tonofibrile, desmosome and tonofilament desmosome complex. However, it was unable to identify the presence of typical keratohyalin granules in these foci.
Discussion was also briefly made on the genesis of dark cell, lymphoid reaction in cancer stroma and the direction of tumor growth.View full abstractDownload PDF (30018K) -
Yoshihito Ban1973 Volume 64 Issue 10 Pages 829-836
Published: October 20, 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSBactericidal activity of iodic antiseptic, Isodine, was stuied by a method similar to that of the Phenol Coefficient. In the early stage of the experiments, bactericidal activity was found to be very labile. After many experiments however, it was found that the dark violet color of Isodine was faded by the peptone in the Trypticase-soy-broth and its bactericidal activity was reduced. To avoid the effect of peptone the saline was used to emulsify the colonies on GAM-agar-plate. 1, 000 times diluted Isodine killed P. aeruginosa (8 strains), E. coli (NIHJ JC-2) and S. aureus (FDA 209-P) within one minute. But 5, 000 times diluted Isodine could not kill those bacteria within 15 minutes. No difference of bactericidal activity was observed between 20°C and 37° incubation.
By mixing serum or urine with Isodine, the fading and the reduction of bactericidal activity also occurred. The fading by protein (+++) urine was stronger than that by protein (-) urine. Just as soon as the material was mixed, the fading came to end.
50 times diluted Isodine, faded by urine containing protein (-), (+) (++) and (+++), killed P. aeruginosa (Tsuchijima) within one minute but 500 times dilution could not kill it within 15 minutes. 100 times dilution killed it within 3 minutes when mixed with protein (-) and (++) urine. But the same solution could not kill it within 15 minutes when mixed with protein (+) and (+++) urine.
The degree of fading was examined when 50 times diluted Isodine was used for the bladder irrigations in a man and a woman with protein (-) urine. The fading occurred very strongly in the first and the second irrigation but weakly in the subsequent irrigations. When the bladder of a man with protein (++) urine was irrigated previously with distilled water twice and then Isodine was used, the fading hardly occurred.View full abstractDownload PDF (2722K) -
Minoru Matsuda, Yoshinori Mori, Kouzi Takahashi, Hazime Nagata, Tsuyos ...1973 Volume 64 Issue 10 Pages 837-846
Published: October 20, 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSDISA-Uroflowmeter, a recently developed momentum mass flowmeter, was tested for its accuracy under various conditions. Up to the flow rate of 50ml/sec, the error deviating from the claimed steady flow lineality fell within the range of ±10%. When the stream was shifted from side to side, as in the case of physiological voiding, the application of conical funnel caused fluctuation of flow rate recordings. Thus at a flow rate up to 10ml/sec, the error fell in an extended range between -54.5% and +44.2%. At a flow rate of 10ml/sec or more, the error is somewhat reduced and detected as between -37.0% and +9.8%. The lag time of recording was determined as 0.2 second, and the time interval required for reaching the plateau value was 1.3 second.
In addition, the present paper is concerned with brief introduction of various available uroflowmeters, their accuracy, structural principles and some problems in clinical use. An emphasis is placed on the interpretation of errors arising from the form of urine collecting system, and the importance of skillfull management of any uroflowmeter including enough recognition of its charactaristics and precise correction of its accuracy.View full abstractDownload PDF (3121K)
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