All issues
Successor
Predecessor
Volume 64, Issue 5
Displaying 1-7 of 7 articles from this issue
- |<
- <
- 1
- >
- >|
-
1. The Changes of the Action Potentials after Ureteral Operation in the Mongrel DogsShuhei Sasaki1973 Volume 64 Issue 5 Pages 363-375
Published: 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSFor the studies on the recovery of ureters from immotility after operation, 24 dogs were used.
Twelve ureters of 10 dogs were incised 1cm long at the center along the direction of the urinary flow, and 14 dogs had 18 ureters sectioned transversely at the center. Immediately after suturing, the incisions were bound side to side, and the sections were sutured end to end. Their peristaltic movements were recorded by taking the uretero-myograms with 2 sets of the bipolar leads made of platinum wire 0.5mm thick, accoding to Kubo et al. Both were implanted into the wall of the ureter; one 1cm upward and the other 1cm downward, each apart from the operational wound.
Whithin one minute after the operation, all but 2 ureters examined showed some waves of the normoperistalsis found in the part proximal to the wound, and in the distal parts of them no wave of the peristalsis.
A half hour later, 70% of ureters examined showed some movements of peristalsis in the distal part, whereas those of the anti-peristalsis were found 2.5 times more frequently than as those of the normoperistalsis.
The waves of the anti-peristalsis in the distal part were taken for 5 days after the incision and for 14 days after the section. Those action potentials recorded had great difference in the discharge intervals from those in the proximal part.
In the course of the observations, 100% of ureters with the wound sectioned and 75% of those with the incisioned had the urinary fistula formed by the wound.View full abstractDownload PDF (3065K) -
2. The Passing-over Rate of Peristalsis along Dog's Ureter after Complete Recovery in Operated SiteShuhei Sasaki1973 Volume 64 Issue 5 Pages 376-382
Published: 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA half of 18 ureters recovered from the operation described in a previous paper showed hydronephrosis.
From the diameter of each ureter in the parts proximal and distal to the operational wound, the cases of hydronephrosis were classified into two groups, mild one (5 cases) and severe (4 cases).
The rate of peristalsis passing over from the proximal part to the distal part along the ureter was analyzed by the uretero-myogram: In the group of non-hydronephrosis, it was 74.2% to the mean value (52 to 100%). In the mild case, it was 37.9% (28.5 to 48.5%). In the severe cases, it was 6.1% (0 to 13.2%).
From the above results, it was suggested that, if the passing over rate of peristalsis did not reach 50%, hydronephrosis may develop.View full abstractDownload PDF (2811K) -
Noriko Sasaki1973 Volume 64 Issue 5 Pages 383-396
Published: 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSThere are various theories concerning the relationship between malignant tumors and bloodclotting, fibrinolytic enzyme system and peptides associated with these enzymes.
1. A dose of 0.02ml/head/day of N-butyl-N-butanol (4)-nitrosamine (BBN) was administered orally to eight-week-old Wistar-Imamichi strain male rats for twelve weeks and then these animals were divided into three groups.
One group was not treated (control group), and the other groups received either low-molecularweight dextran (LMW-dextran), which shows lipoprotein-lipase activity and fibrinolytic activity (LMWdextran group), or p-amino-methyl-benzoic acid (PAMBA), which shows antifibrinolytic activity (PAMBA group), each three times intraperitoneally.
These animals were sacrificed at the ninth week after completion of BBN administration.
2. Incidence of experimentally induced bladder tumor in the control group, LMW-dextran group and PAMBA group were 76.5% (13 out of 17 rats), 60% (three of five) and 56% (five of nine) respectively.
3. When the group suffering from bladder tumor was compared with the other without tumor, the former had a tendency of increase in fibrinogen and fibrinolytic activity and of decrease in antifibrinolytic activity in plasma.
4. The tumor tissue had a tendency to have larger amount of fibrinogen, tissue thromboplastinlike substance and higher fibrinolytic activity than non-tumor tissue.View full abstractDownload PDF (6524K) -
Masuhiro Noda, Yoshiyuki Hashimoto1973 Volume 64 Issue 5 Pages 397-401
Published: 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSCarcinogenic effect of N-butyl-N-butanol (4) nitrosamine (BBN) and its acetate (BBN-Ac) was studied in ACI/N rats. The possibility of iso-transplantation of the cancer thus formed was also studied.
Fifty-seven male rats were divided into 5 groups as follows;
Group A: 20ml of 0.01% BBN was given daily for 25 weeks.
Group B: 4ml of 0.05% BBN daily and 20ml of water twice a week for 25 weeks.
Group C: 20ml of 0.05% BBN daily for 25 weeks.
Group D: 20ml of 0.06% BBN-Ac daily for 25 weeks.
Group E: 20ml of water daily as a control.
Thirty-eight to forty weeks after the beginning of the administration, urinary bladder, kidney, liver, lung and lymph nodes were examined histologically.
In groups A, C and D, papillomatous tumors of the urinary bladder were found in all of the animals and 27%, 90% and 100% of them were identified as cancer, respectively. The nature of the cancer was the transitional cell carcinoma in most cases and some of them were accompanied with squamous cell metaplasia.
In the group B, hyperplasia of mucous membrane, papilloma and papillary cancer of the urinary bladder were seen in 4, 8 and 1 (8%) cases, respectively. The low rate of the development of the cancer in this group seems to be contrary to the expectation that a limited water supply would result in a greater rate of the development of bladder cancer owing to a long retention of concentrated urine in the bladder.
The bladder carcinomas were transplanted subcutaneouslly into ACI/N rats. Palpable tumors developed in one week and the recipients died in 12 to 117 days.
Sub-transplantations were all successful and 5 lines of transitional cell carcinoma and 2 lines of transitional cell carcinoma accompanied with squamous cell metaplasia were thus established.
One of the transitional cell carcinoma with squamous cell metaplasia was transplanted intraperitoneally. A similar successful result was obtained.View full abstractDownload PDF (1928K) -
Report 1. Classification of Escherichia Coli Isolated from Urine by Multiple Rabbit Antiserum for Pathogenic Escherichia ColiShiro Kawano, Motohiro Iihoshi, Hiroyuki Hashimoto, Shiro Yarimizu, Yo ...1973 Volume 64 Issue 5 Pages 402-407
Published: 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSIt is well known that the most common causee of urinary tract infection is Escherichia coli. Since 1943, serological classification of E. coli dependent upon O and K antigens has been established by Kauffman and some other workers. It has been demonstrated in intestinal infection that there were some specific relationships between serological character of E. coli and its pathogenicity. However, little is known about serological characteristics of E. coli in urinary tract infection. The purpose of the present study is to investigate on the relationships between serological types of E. coli isolated from urine and therapeutic results in urinary tract infection.
E. coli isolated from the urine of 124 cases with uncomplicated infection of the urinary tract were classified into four types, serotype 0, I, II and III, according to the results of agglutination reaction for three kinds of multiple rabbit antiserum for pathogenic E. coli prepared at the Kitazato laboratory (Table 1). Relationships between these serotypes of isolated E. coli and clinical results of chemotherapy according to the authors' criteria were also observed.
The results obtained were as follows.
1) The most frequent type of E. coli which was seen in 71 of 124 cases (57.2%) was serotype 0, which showed no positive reaction to all of three kinds of antiserum. Serotype I which showed positive reaction to antiserum I was seen in 43 cases (34.7%). Serotype II reacting to antiserum II was seen in only 2 cases (1.7%) and Serotype III reacting to antiserum III was seen in the remaining 8 cases (6.6%).
2) Agglutination test by single antiserums revealed that 42 of 43 strains of serotype 0 were O86aK62 and the other one was O86aK61, both 2 of serotype II were O119K69, and of 8 serotype III strains, 4 were O28acK73, 2 were O44K74 and the other 2 were O125K70.
3) Of 71 cases with serotype 0 E. coli, 59 (83.1%) were cured by chemotherapy. In the cases with serotype I, 28 of 43 cases (65.1%) were cured. Both of 2 cases with serotype II were not cured and 7 of 8 cases with serotype III were cured.
4) The results suggest that some pathogenic E. coli in the intestinal tract may be the cause of urinary tract infection.View full abstractDownload PDF (795K) -
Kimio Fujita1973 Volume 64 Issue 5 Pages 408-411
Published: 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA 67-year-old man was admitted to a neighboring hospital, complaining dysuria, and received retropubic prostatectomy under the diagnosis of benign prostatic hypertrophy on Feburary 9, 1972. The report was not conclusive but suggested leiomyoma mass attached to normal prostate. Several months later dysuria developed again. He was first seen at this clinic in August 1972. He had a large intrapelvic tumor, which was noted at the region of seminal vesicle on rectal palpation. Radical surgery was impossible. Ileal conduit was formed and colostomy was done on August 24.
Histologically, the biopsy specimen showed the appearence of leiomyosarcoma. The cells were highly pleomorphic, and many giant cell forms were present. The nuclei were hyperchromatic and numerous mitotic figures were present.
The patient was treated with tele-cobalt radiation therapy. He improved considerably and was discharged. He shows no evidence of metastasis at present time.
In a review of the literature in 1941, Prince and Vest stated that leiomyosarcoma is the solwest growing and least malignant sarcoma of the prostate, and must be a well difined entity. Study of recorded cases in this country and re-evaluation of world wide cases shows poor prognosis of sarcoma of this type like other types of prostatic sarcoma. But some cases suggest that radiotherapy and chemotherapy is effective at times. The primary treatment, as a rule in all malignancies, must be radical excision in early stage.
There are two hypotheses for its histogenesis. One is that they arise from the muscle fibers in theprostate; the other is from the embryonal remnant neighboring or in the prostate. In most cases the precise origin could not be determined. In this case the origin is, at least, not same as that of benign hypertrophy.View full abstractDownload PDF (2170K) -
Atsuo Kondo, Hajime Torii1973 Volume 64 Issue 5 Pages 412-414
Published: 1973
Released on J-STAGE: July 23, 2010
JOURNAL FREE ACCESSA case of incomplete subsymphyseal epispadias is reported, which is the first report in Japan. The patient was a four-year-old boy, whose penis was spade-like-shaped and with an accessory urethra ending blind in the subsymphyseal portion besides the mormal urethra and urethral orifice. Fistulectomy was carried out; urinary incontinence was not observed before and after the operation. A few hypotheses on the formation of epispadias were discussed.View full abstractDownload PDF (1705K)
- |<
- <
- 1
- >
- >|