Nippon Shokakibyo Gakkai Zasshi
Online ISSN : 1349-7693
Print ISSN : 0446-6586
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Volume 103, Issue 7
Displaying 1-9 of 9 articles from this issue
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Review article
Monthly report; Colorectal and small bowel cancer risk in patients with inflammatory bowel disease
Original article
  • The study of the autopsies of six patients with progressive esophageal cancer to investigate complications caused by esophageal stents
    Yuya NAKAMURA, Masaho OTA, Yosuke IZUMI, Nobuaki FUNADA
    2006 Volume 103 Issue 7 Pages 812-818
    Published: 2006
    Released on J-STAGE: July 05, 2006
    DOIhttps://doi.org/10.11405/nisshoshi.103.812
    JOURNAL FREE ACCESS
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    Endoscopic placement of metal stents are used widely for patients with esophageal obstruction and fistula due to progressive esophageal cancer, but cause high rate of severe complications associated with the immediate causes of death. To determine severe complications caused by stents, we studied clinical data and autopsy of six patients who had been treated with stents for inoperable progressive esophageal cancer. Occording to the clinical records only two patients had severe complications due to stents. But at autopsy, three patients had massive hemorrhage in the stent placement, one patient had mediastinitis, and one patient were in imminent danger of perforation whose stent had been incorporated into the adventitia of the wall. More severe complications were revealed than those expected clinically. Endoscopic placement of metal stents have a great deal for the improvement of quality of life. But we should carefully decide the indication because endoscopic placement of metal stents could cause severe complications associated with the immediate causes of death.
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  • STI571 for GIST
    Masayoshi NAKANISHI, Akinori NOGUCHI, Hiroki TAKESHITA, Yusuke YAMAMOT ...
    2006 Volume 103 Issue 7 Pages 819-826
    Published: 2006
    Released on J-STAGE: July 05, 2006
    DOIhttps://doi.org/10.11405/nisshoshi.103.819
    JOURNAL FREE ACCESS
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    Since the effectiveness of STI571 for GIST was reported, therapy for GIST has changed markedly, and the disease has attracted attention. We have treated 19 patients with GIST since 2000 by 19 resections (local resection in 14 patients, total gastrectomy in 2 patients, distal gastrectomy in 2 patients, and hepatectomy in 1 patient), and administered STI571 to 5 patients with unresectable or recurrent GIST. Of these 5 patients, 2, 1, 1, and 1 had PR, SD, PD, and inevaluable disease, respectively, with a response rate of 50%. The disease was controllable in 80% of the patients. All patients had palpebral and crural edema as side effects, which were not severe, suggesting the safety of the drug. It is important to tailor therapy (STI571 or surgery) to the patient.
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Case Report
  • A case of gastric endocrine cell carcinoma with liver metastasis showing rapid growth during pregnancy and marked reduction by systemic chemotherapy after delivery
    Akemi SHIRADO, Hirofumi UTO, Kazunori KUSUMOTO, Joji KUROGI, Hidemori ...
    2006 Volume 103 Issue 7 Pages 827-832
    Published: 2006
    Released on J-STAGE: July 05, 2006
    DOIhttps://doi.org/10.11405/nisshoshi.103.827
    JOURNAL FREE ACCESS
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    A 28-year-old woman was given a diagnosis of gastric endocrine cell carcinoma with multiple liver metastases in 1997. Chemotherapy was administered for treatment after a distal gastrectomy and hepatic tumor resection, and she had shown no sign of relapse after 2002.
    In February 2004, she was in the third month of pregnancyC and experienced recurrent liver metastasis. Although the tumor grew rapidly from 3cm to 10cm during her pregnancy, its size was significantly reduced with systemic chemotherapy after delivery. This is a rare case in which a liver metastasis of a gastric endocrine cell carcinoma grew during the course of pregnancy.
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  • A case of gastric hamartomatous inverted polyp (submucosal tumor type) accompanied by gastric cancer
    Shoji HIRASAKI, Masahito TANIMIZU, Junichirou NASU, Junro KATAOKA, Min ...
    2006 Volume 103 Issue 7 Pages 833-838
    Published: 2006
    Released on J-STAGE: July 05, 2006
    DOIhttps://doi.org/10.11405/nisshoshi.103.833
    JOURNAL FREE ACCESS
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    Endoscopic examination of a 39-year-old woman revealed a flat-elevated submucosal tumor (SMT) in the upper third area of the stomach and a IIc lesion in the anterior wall of the lower third of the stomach. Endoscopic ultrasonography findings suggested an aberrant pancreas. Both lesions were resected by distal gastrectomy. Histological examination of the SMT revealed the dilated glands with cyst formation and proliferation of smooth muscle bundles in the submucosal layer, and it was diagnosed as a gastric hamartomatous inverted polyp. The IIc lesion was a signet ring cell carcinoma. Cases of gastric hamartomatous inverted polyps coexistent with gastric cancer have been rarely reported in Japan.
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  • A case of alcoholic liver cirrhosis associated with intramuscular hematoma
    Hideki TOZAWA, Shinya KOBAYASHI, Azuma MURAMATSU, Chihiro HASEGAWA, To ...
    2006 Volume 103 Issue 7 Pages 839-843
    Published: 2006
    Released on J-STAGE: July 05, 2006
    DOIhttps://doi.org/10.11405/nisshoshi.103.839
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    We reported a rare case of spontaneous intramuscular hematoma associated with alcoholic liver cirrhosis patient. A 60-year-old man with alcoholic liver cirrhosis was admitted to our hospital for pneumonia. It was improved by conservative treatments, howeverC he was complaint of severe pain in right hip and thigh. MRI revealed intramuscular hematoma at acute phase. Resting and anticoagulant therapy reduced it, but liver functions were not improved. After a few months, he received another intramuscular hematoma in the left thoracic muscles, and then died because of liver failure. It seems important to consider intramuscular hematoma as a complication of alcoholic liver cirrhosis.
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  • A case of pancreatic intraductal papillary-mucinous carcinoma with penetration to the stomach and splenic abscess.
    Kazuyuki KANEMASA, Yoshio SUMIDA, Shigeyoshi IMAMURA, Naho KATOH, Shun ...
    2006 Volume 103 Issue 7 Pages 844-850
    Published: 2006
    Released on J-STAGE: July 05, 2006
    DOIhttps://doi.org/10.11405/nisshoshi.103.844
    JOURNAL FREE ACCESS
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    We report the case of an 80-year-old man given a diagnosis of pancreatic intraductal papillary-mucinous carcinoma (IPMC) and early gastric cancer. He refused surgery, therefore endoscopic mucosal resection (EMR) for gastric cancer and careful observation were performed. Penetration of the IPMC to the stomach was observed 3 months later. Ten months after the initial diagnosis, he was found to have a splenic abscess and was subsequently treated by antibiotics and percutaneous drainage, and a fistula between the IPMC and the splenic abscess was observed. We suppose IPMC penetration to the spleen and bacterial transmission from the stomach through the fistula caused the splenic abscess. While IPMC is recognized as a low-grade malignancy, some cases of invasive carcinoma with fistulation to adjacent organs have been reported. To the best of our knowledge, this is the first case of IPMC associated with splenic abscess due to pancreato-splenic fistula.
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