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Volume 72, Issue 10
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[in Japanese]1975 Volume 72 Issue 10 Pages 1231-1239
Published: 1975
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSDownload PDF (1103K) -
Toshio HATTORI1975 Volume 72 Issue 10 Pages 1240-1251
Published: 1975
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSThe morphorogical study of gastric arterial constriction, one of the causes of restraint ulcer, is performed by using the rats of male Whister descent, and by the methods of water plus restraint, administration of drugs, combining with block agent and post hypothalamus electro-stimulation.
The constriction rate of perinuclear vacuoles (by Takeuchi) is investigated, at the same time, E.M.G. of stomach is also studied and gets a result as follows.
1) All bleeding or bleeding erosion of gastric mucosa after water plus restraint are observed and the constriction rate of perinuclear vacuoles is high value. The fact, ischemic changes of gastric mucosa caused by arterial constriction is one of the reasons of causing bleeding or bleeding erosion.
2) The prosperity and decay of perinuclear vacuoles in administration of noradrenaline shows the constriction rate of perinclear vacuoles begins to increase after 1 minute, reaches to top after 5 minutes, but returns to the value as same as the control group after 60 minutes. This is suggested that perinuclear vacuoles appear cousing of constriction of artery, and is reversibility.
3) In the E.M.G. of stomach shows a spasm of smooth muscle by administration of acetylcholine but low constriction rate of perinuclear vacuoles is noticed.
4) In group of combining with block agent (block agent of α-receptor, phenoxybenzamine), there is no any changes in gastric mucosa and low constriction rate of perinuclear vacuoles is found in noradrenaline group or water plus restraint group. This is suggested that catecholamine is stand between restraint and vasoconstriction.
5) Bleeding of gastric mucosa in the group of post hypothalamus electro-stimulation is observed 40%, and the constriction rate of perinuclear vacuoles is showed high. This is suggested that stimulation of sympathic nervous system bring to vasoconstriction and changes of gastric mucosa.View full abstractDownload PDF (2075K) -
Fumio KONISHI, Hideaki SAITO, Akira ASANO1975 Volume 72 Issue 10 Pages 1252-1256
Published: 1975
Released on J-STAGE: December 26, 2007
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Ikuo TABATA1975 Volume 72 Issue 10 Pages 1257-1269
Published: 1975
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSSo far the author has performed endoscopic pancreatocholangiography 994 times and studied the pancreatograms of pancreatic carcinomas in this paper. The endoscopic pancreatogram was succeeded in 54 out of 63 patients with pancreatic carcinoma which were confirmed by operation or autopsy.
The pancreatograms of pancreatic carcinoma were classified into 4 types, the obstructed type (61%), the stenosed type (31%), the mixed type (6%), and the normal type (2%).
The shape of obstructed portion in the main pancreatic duct was nib-like in 17%, irregular surfaced in 58%, spoon-like in 22% and flat in 3%, and the shape of stenosed portion was irregular surfaced in 80% and not so in 20%.
It was emphasized that the differential diagnosis between pancreatic carcinoma and other pancreatic diseases was not so easy in some patients by the pancreatograms alone.View full abstractDownload PDF (3062K) -
Kanji MIENO, Takeo NOGUCHI, Tatsuo YAMAKAWA1975 Volume 72 Issue 10 Pages 1270-1276
Published: 1975
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSEighty-two post-operative choledochoscopy for 43 patients were performed through the fistula after T-tube was removed. Post-operative choledochoscopy was formerly carried out in the X-ray room so that selective cholangiography with insertion of a thin teflon tube or back-flushing catheter into the desired locations could be immediately obtained whenever any doubt in endoscopic diagnosis existed. Selective cholangiography in conjunction with choledochoscopy seems to be the most reasonable approach as a diagnostic test, because cholangiography alone is usually inconclusive.
Moreover, post-operative choledochoscopy can be performed repeatedly if T-tube fistula is kept patent and is useful procedure for observation of biliary tracts as well as treatment for retained biliary calculi and intrahepatic calculi. The importance of employing post-operative choledochoscopy as an adjunct to conventional roentgenological examination was strongly advocated.View full abstractDownload PDF (1775K) -
Kaoru SHIMADA, Takashi INAMATSU, Moriya YAMASHIRO, Kyotaro KANAZAWA, H ...1975 Volume 72 Issue 10 Pages 1277-1281
Published: 1975
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSAlthough a considerable number of bacteriological investigation of bile has been carried out, very few used good anaerobic techniques. Clostridium welchii was noted to be the most common anaerobe in bile, and few reports have mentioned Bacteroides fragilis. Since B. fragilis is the most prevalent organism in intestinal flora and has frequently been isolated from the abscess of the liver, one can imagine that biliary tract is often infected by this anaerobe.
In this series, anaerobic and aerobic culture of the gallbladdlr bile was performed on the forty consecutive cases of biliaty tract surgery. Ten patients had sterile bile. Thirteen specimen yielded anaerobes as well as aerobes, and 17 yielded only aerobic bacteria. E. coli was the most common organism (25 strains), and B. fragilis (11 strains) was the most frequently encounted anaerobes, which, next to Klebsiella-Enterobacter (20 strains), stood third among all the isolates in this study. Cl. welchii was found in 6 bile specimen.
Frequent isolation of anaerobes, especially of B. fragilis, may be related to the anaerobic techniques used, and to background factors, for example, the age of the patients and high incidence of pigment stone.View full abstractDownload PDF (598K) -
Makoto OTSUKI, Susumu SAEKI, Hosai YUU, Tsutomu KANDA, Mitsuo MAEDA, M ...1975 Volume 72 Issue 10 Pages 1282-1290
Published: 1975
Released on J-STAGE: December 26, 2007
JOURNAL FREE ACCESSAmylase isoenzyme determination, using a simple thin layer of 1mm polyacrylamide gel electrophoresis, was performed in an attempt to identify the source of individual isoenzyme and which isoenzyme was related with which disease. In sera of 500 normal subjects, 2 major bands and 2 to 4 minor bands wans differentiated with this method. All these isoenzymes migrated similarly to salivary or pancreatic isoramylases. From the findings of electrophoretic mobility studies of saliva, pancreatic juice and sera of patients with mumps, acute pancreatitis, pancreatectomy and salivary gland hypofunction, it could be said that Amy SE-1, 2, 4, 6, 8 were pancreatic tpye and Amy SE-3, 5, 7 wrer salivary type. Although Amy SE-4, 6, 8, could not be observed in normal subjects, they appeared in sera with elevated amylase activities. However no correlationship was found between the severeness of diseases and the appearance of these isoezymes. Three patterns of amylase isoenzymes were observed in post-operated patients with elevated serum amylase activities; only the isoamylase activity of pancretic type was increased, the activity of salivary type isoenzyme was increased and the activities of the both types were increased. Especially, the high amylase activity of salivary type was observed in patients with post-thoracic surgery using a heart-lung machine. On the other hand, the serum amylase activity in patients with chronic pancreatitis were low normal or below normal range and electrophoretic separation of serum amylase into isoenzymes revealed that Amy SE-1 (pancre+atic type) was decreased as low as 17.6%.
From these observations, it can be said that amylase isoenzyme determination may be a great help for exact diagnosis.View full abstractDownload PDF (1432K)
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