This study aims to clarify the effects of deoxyribonucleic acid (DNA) processed knitted fabric on human skin activity. We used two kinds of DNA, that is, the nucleoprotein extracted from salmon milt and the oligoDNA treated nucleoprotein with enzyme. The oligoDNA contains over 85% DNA. To determine the effects of oligoDNA application, the first experiment was a direct application method that applied an aqueous solution of oligoDNA powder directly to the inside of the upper arm for 14 weeks. The condition of the skin, measured by the water content of the skin, water evaporation from skin, tensile recovery, the microscope images of the replicas of skin surface and subjective feeling showed good results. Therefore, the second experiment applied the oligoDNA by using fabric. Arm bands were made of the knitted fabric processed with the oligoDNA solution and wearing tests were conducted. But this processed fabric was not useful. So, we used the nucleoprotein instead of the oligoDNA and modified the concentration of the solution. The nucleoprotein contains about 40% of DNA and about 60% of protamine. The results showed that the condition of human skin was affected by the modified processed fabric. The effects of the processed fabric on the skin condition were found in the water content of the skin, tensile recovery and the microscope images of the replicas of skin surface after four weeks had passed.
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