Post-operative complication of lobectomy was studied on one hundred tuberculous patients. The results were summarized as follows:
1) Bacteriological finding.
Prior to operation, 39 out of 100 patients were sputa negative on smear and culture, 2 of them were sputa positive on smear and were negative on culture, and 56 of them were sputa positive on culture. Resected materials from same 100 patients were examined. As a result, 22 were negative on smear and culture, 12 were positive on smear and negative on culture, and 66 were positive on culture. There were differences in findings of bacilli between of sputa obtained prior to operation and of resected materials. But significant difference was not demonstrated in ratio of resistant bacilli between of that sputa and of the resected materials.
2) Histogical finding of bronchi of resected lung.
Tuberculous changes located in the proximal parts of bronchi of resected lobes were found more frequently in cases with resistant bacilli than in those with non-resistant bacilli.
3) During one or two years after operation, two bronchial fistulas combinated with pyothoraxes, one tuberculous pyothorax, and four cases (which were) progressive observed.
4) Status of bacilli in sputa examined before operation and post-operative complication.
There were no complication in 41 patients with negative sputa. One patient out of 30 with lowly positive sputa and 6 patients out of 18 with highly positive sputa had complication after operation.
5) Post-operative chemotherapy and complication.
Post-operative chemotherapy was performed as follows:
A: SM, PAS, INH
B: VM, PAS
C: PZA, INH
Post-operative complication were found in one patient out of 6 of group A which had SM·INH resistant bacilli, one who was treated with PZA plus INH and had SM·INH resistant bacilli, and four patients out of 18 of group B which had resistant bacilli against SM·PAS·INH.
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