医療
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
19 巻, 5 号
選択された号の論文の12件中1~12を表示しています
  • 高藤 歳夫, 立沢 貞彦, 坂本 光弘, 榎本 尚美
    1965 年 19 巻 5 号 p. 369-372
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
  • 吉田 綾子, 山形 豊, 荒井 進
    1965 年 19 巻 5 号 p. 373-377
    発行日: 1965年
    公開日: 2011/12/02
    ジャーナル フリー
    The combined therapy of Antigène methylique and antituberculous drugs were used on nineteen cases who had positive AFB in sputum and were mostly found thick-walled cavities on chest x-ray examination (group I), and potassium iodid in -addition to this combined therapy were administered to 21 cases who had occasional positive AFB in culture. (group J).
    Antigén methylique, prepared in Pasteur Institute, injected intramuscularly with gradual increasing dsis for eight days monthly. These treatments were undertaken on each group for six months.
    The results are as follows:
    Negativity and diminishing in number of tubercle bacilli on culture were proved in 7 cases of the group I, and in 11 cases of the group II.
    Slight improvement of the cavities was noted in 8 cases, and enlargement of it was noted in 3 cases on x-ray film.
    Kaolin agglutination rate increased during the first one to tWo months under the treatment, however, decreased extremely at the end of this treatment.
    It is considered that this treatment is worthy to be tried for chronic pulmonary tuberculosis with positive bacilli in sputum, when the usual, antituberculous chemotherapy does not attain its purpose.
  • 太田 真, 富沢 学
    1965 年 19 巻 5 号 p. 378-383
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
    The untreated patients presented cavities and positive AFB in 60-70% at the time of admission. By adequate treatment after staying for 1 year in the sanatorium, cavities and AFB were decreased to 1-14%.
    On the contrary, the patients, who had been already treated at home or at the other medical facilities, showed still cavity formations and positive AFB in 80%, despite of over one year period of treatment before admission.
    Thus total treatmentsterm and amount of antibiotics of untreated group were about a half of those of treated group. Moreover, the later received surgery in higher rate (ca. 60%) than the former (ca. 7%), thet resulted low respiratory func-tion after recovery.
    Therefore, from every point of view, the first 1 year of treatment for tuberculosis is the most important and seems to influence the prognosis.
  • 山本 直明, 手嶋 格
    1965 年 19 巻 5 号 p. 384-395
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
    A) It has been a focus of medical interest that the activity Of lactic dehydrogenase in serum (SLD) is of some value as an adjuvant tool in diagnosing malignancies.
    To asses the diagnostic value of this enzyme, SLD was determined in 470 cases with malignancies and other diseases.
    The method of Wróblewski and La Due with some slight modifications was used for the determination of SLD. in this study.
    1) In 263 cases with malignancies, the range of SLD levels was 157 and 9550. Though the elevation was of course not a sine qua non in malignancies, it is certain that there was a tendency to elevate SLD levels in malignancies, Marked elevations were found in hepatomas, leukemias and cases with widely spread metastasis in any kind of cancer, particularly with metastasis to the liver.
    2) In non-tumor diseases, three major categories were examined.
    a) In acute hepatitis or liver cirrhosis, elevations of medium ;range were commonly found, and when the course was favorable, the activity l lowered gradually.
    b) In myocardial infarction SLD was markedly elevated in their acute phasis, and when the injuries subsided uneventfully, the SLD level lowered, gradually. The speed of reduction, however, in much slower than that of S-GOTT
    c) In pulmonary tuberculosis or suppurative lesions in the lung, SLD levels within the normal range were found in the majority of the cases.
    B) The ratio of serous fluid to serum activity for lactic dehydrogenase (LD) was determined in 54 patients with effusions due to various diseases.
    In 56% of the 32 patients with malignant neoplasms had ratios of more than 1. 0.
    In 75% of the patients with inflammatory in nature, however, had too high ratios.
    The results of this study indicate that the activity in the effusion fluid of LD investigated does not clearly differentiate malignance from benign effusion.
  • 武田 吉正, 佐藤 啓
    1965 年 19 巻 5 号 p. 396-401
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
    In order to establish the clinical diagnosic value as well as the prognostic significance of the serum enzymatic activity, the author investigated the fluctuations of SCOT, SLDH and SALD levels in several diseases and in experimental dogs.
    1) SGOT, SLDH and SALD values were evaluated as that they change parallel with the severity of hepatitis or myocardial infarction.
    2) In cardiac insufficiency including valvular diseases, slight insufficiency with only hepatic congestion showed increase of SLDH only, severe insufficiency with edema in lower extremities and or cardiac asthma presented significant increase of SLDH as well as SALD, and the latter indicates secondary liver change resulted by circulatory disturbances.
    3) The comparative and serial estimation of these serum enzymatic activity in these diseases revealed that the maxitum values of the activity occur in a definit order according to the process of recovery: at first SCOT, next comes SLDH, and SALD is the last one.
    This finding is apparently helpful for the diagnosis especially of myocardial infarction, These characteristic changes of enzymatic activity were confirmed in experimental dogs with artificial myocardial infarction.
    4) In contrast with those in cardiac and/or hepatic diseases serum enzymatic activity in gastritis, diabetes mellitus and hypertention revealed within normal limits.
  • 伊藤 昭二
    1965 年 19 巻 5 号 p. 402-407
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
    Alkaline phosphatase and 5- nucleotidase activity of peripheral neutrophils were cytochemically studied on healthy persons and severe pulmonary tuberculosis.
    1) The alkaline phosphatase activity of peripheral neutrophils was significantly increased in the Tbc patients, while 5-nucleotidase activity showed no significant difference between these two groups.
    2) No intimate correlation was found between neutrophil counts and enzyme activities not only in the healty persons but also in the Tbc patients.
  • 菱本 恒温, 井唯 信友, 出井 騰重
    1965 年 19 巻 5 号 p. 408-413
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
    It has been generally accepted that the enzymatic determination of blood glucose is most rapid, simple and exact specific to glucose. Commercially availablee four kits were evaluated and found to be satisfactory in routine clinical determination so far tested, although each kits have their own characteristics.
    However, existed inhibitory substances in blood might have caused the error of the exact determination. These substances did not inhibit the enzymatic reaction itself, but they reacted with hydrogen peroxide liberated in the reaction sequence, thus caused the error of the determination.
    In order to make the test simple and rapid, possibility to neglect the deproteinizing procedure was tested using the smaller amount of sample and the increased amount of reagents, but resulted without success to have exact value of the determination.
  • 喜多島 豊三
    1965 年 19 巻 5 号 p. 414-417
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
  • 春畑 喜朔, 高 橋暁
    1965 年 19 巻 5 号 p. 418-421
    発行日: 1965年
    公開日: 2011/12/02
    ジャーナル フリー
  • 寺崎 平, 木村 忠, 隈本 郁郎, 加庭 信二
    1965 年 19 巻 5 号 p. 422-424
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
  • 関谷 忠雄, 板谷 純治, 吉村 鏡子
    1965 年 19 巻 5 号 p. 425-428
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
  • 田村 政司, 中嶋 正, 牛窪 滋樹, 植木 喬
    1965 年 19 巻 5 号 p. 429-432
    発行日: 1965年
    公開日: 2011/10/19
    ジャーナル フリー
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