西日本皮膚科
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
32 巻 , 6 号
選択された号の論文の10件中1~10を表示しています
図説
症例
研究
  • 中垣 謙一
    1970 年 32 巻 6 号 p. 509-529
    発行日: 1970/12/01
    公開日: 2012/03/26
    ジャーナル 認証あり
    Influences of climate on the occurrence of infectious skin diseases were investigated statistically by collecting the clinical records of two hospitals around Fukuoka district during 3 years. The results were them examined with the statistical methods (X2 test and Fisher’s exact probability test) and the following results were shown to be significant with a confidence limit of 95%.
    (1) Trichophytia pompholyciformis, Trichophytia eczematosa marginata, Pityriasis versicolor and Impetigo bullosa increased with high air temperature (above 16.2°C), high humidity (above 71.8%), long duration of sunshine (above 169.2h) and low atmospheric pressure (under 1014.6mb).
    (2) Multiple sweatgland abscesses of infants showed almost same tendency as (1) except that no correlation was observed with humidity.
    (3) Folliculitis increased with high temperature and long duration of sunshine.
    (4) Varicella increased with low temperature and short duration of sunshine.
    (5) Herpes zoster increased with much precipitation (volume of rain, above 116.1mm) and low atmospheric pressure. (Limits to judge each climatic factors “high” or “low” were their mean value; temperature 16.2°C, humidity 71.8%, duration of sunshine 169.2h, atmospheric pressure 1014.6mb, precipitation 116.1mm)
  • 末永 義則
    1970 年 32 巻 6 号 p. 530-538
    発行日: 1970/12/01
    公開日: 2012/03/26
    ジャーナル 認証あり
    Griseofulvin could be assayed by gas chromatographic method. A Shimadzu GC-3AE instrument equipped with an electron-capture detector of pulse type and 2,000×4mm of glass column packed with 1.5% SE-30 on Chromosorb W (60-80 mesh) was employed. In the refining process of griseofulvin from extract, chromatography on 70×6mm Florisil colum was applied. Serum griseofulvin levels in 5 rabbits given simgle oral doses of 30mg/kg showed maximum concentration of 0.57∼1.50 μg/ml at 8 or 12 hours after administration, and decreased to 0.15∼0.30 μg/ml at 24 hours. Skin griseofulvin levels in the same rabbits showed maximum concentration at 4 hours in one case and at 8 or 12 hours in other cases, and it was 0.38∼0.83 μg/g. They decreased 0.07∼0.18 μg/g at 24 hours in all cases. In rabbits, skin griseofulvin levels paralleled serum griseofulvin levels and the former was lower than the later for the most part. Serum griseofulvin levels in 5 human subjects given single oral doses of 500mg showed maximum concentraton of 0.30∼2.30 μg/ml at 4 or 8 hours and decreased to 0.30∼1.04 μg/ml at 24 hours.
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