We report herein on a case of cervical spinal meningioma in a 29-year-old woman, which presented as a subcutaneous mass of the neck, and fine needle aspiration cytology was performed. Cytological analysis revealed spindle cells in loose clusters or syncytial arrangements. The nuclei were ovoid with finely granular, evenly distributed chromatin. Nucleoli were inconspicuous, and intranuclear cytoplasmic invaginations were noted. The diagnosis of meningioma was histologically confirmed in the surgical specimens. Although uncommon, meningioma should be considered in the differential diagnosis of any tumor in the neck.
We report on a case of recurrent meningioma located in the left parietal region in a 47-year-old man. A smear/crush preparation obtained at the intraoperative consultation showed not only typical features of meningioma such as whorl formation and intranuclear cytoplasmic inclusions, but also an unusual cytomorphologic feature of a few mitoses. The diagnosis of atypical meningioma was established by the results of the histological and immunohistochemical stainings of the permanent sections. The present case indicated that cytology of smear preparations is useful in arriving at the final diagnosis of atypical meningioma.
We here report a case of Pulmonary Langerhans cell histiocytosis (PLCH) diagnosed by imprint cytology obtained from thoracoscopic biopsy. Intraoperative tumor imprint smears showed Langerhans cells in a background with eosonophils, macrophage, and lymphocytes. Langerhans cell having noched nuclei and abundant cytoplasm with pseudopodia-like projections. The differentiation of Langerhans cells are epithelioid cells or the cells derive from epithelioid hemangioendothelioma. Langerhans cell can diagnose through the above remarks. In our case since the diagnosis of PLCH was made based upon characteristic cytological findings, cytology was useful in diagnosing PLCH.