Chordoma is a rare low-grade malignant neoplasm, commonly found in the sacrococcygeal region and clivus of adults. The tumor is extremely rare in children. A case of chordoma diagnosed by nasopharyngeal biopsy in a 5 year-old-boy is reported. During surgery for the clinical diagnosis of adenoid hyperplasia, specimens were submitted for frozen section diagnosis. Imprint cytology showed typical physaliphorous cells occurring in clusters. A postoperative MRI revealed a lobulated tumor measuring 6 cm in size extending from the clivus to the nasopharynx, visualized as a hyperintensity. Cytology is useful for the diagnosis of chordoma, especially in very rare cases like this one.
We report a case of pilomatricoma diagnosed in a 3-year-old girl. Fine-needle aspiration smear of the cheek nodule revealed uniform tightly packed aggregates of basaloid cells with a high nuclear/cytoplasmic ratio and round nuclei containing nucleoli. Histopathological study of the resected tumor confirmed the diagnosis of pilomatricoma. Cytodiagnosis of pilomatricoma may be difficult because of the presence of basaloid cells, which can be misdiagnosed as carcinoma. However, the absence of nuclear pleomorphism and coarse chromatin, and the presence of tight aggregates of basaloid cells may allow ruling out of the presence of malignancy.
Manson’s sparganosis, which can affect any of various sites of the body, was recognized as a breast mass in a 66-year-old woman. The infection manifested as a breast mass measuring 13 mm in diameter detected by ultrasonography and mammography. Breast cancer was suspected initially and the microbe was detected by fine needle aspiration. Hematological and immunoserological examinations revealed no significant abnormalities. Since this disease is generally transmitted by the intake of unboiled water or raw meats, including of snakes, chickens, etc., the dietary history is useful for the diagnosis. In our patient reported here, the route of infection could not be ascertained, because she gave no history of drinking unboiled water or consuming raw meat.