VITAMINS
Online ISSN : 2424-080X
Print ISSN : 0006-386X
Volume 54, Issue 3
Displaying 1-11 of 11 articles from this issue
  • Toru NAGASAWA, Nobuhiro MORI, Yoshiki TANI, Hideaki YAMADA
    Article type: Article
    1980 Volume 54 Issue 3 Pages 77-88
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
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  • Emiko MORITA, Nobuyasu MIZUNO
    Article type: Article
    1980 Volume 54 Issue 3 Pages 89-93
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
    Metabolism of 3,4'-O-isopropylidene pyridoxine (3,4'-IPP) and 4',5'-O-isopropylidene pyridoxine (4',5'-IPP) was studied in rats. Following an oral or intraperitoneal administration of 3,4'-IPP, urinary excretion of pyridoxine (PN) was about 2~5% of the administered dose at mole base. About 20% of orally administered 4',5'-IPP were excreted as PN in the urine, but about 1~2% were detected as PN in the urine after an intraperitoneal injection. A metabolite of 4',5'-IPP in the urine was separated and purified by chromatographic techniques. The metabolite was assumed to be 4',5'-IPP 3-sulfate by measurement of Rf values on thin-layer chromatography and ultraviolet absorption spectra, identification of acid hydrolyzed product and detection of sulfate ion after acid hydrolysis.
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  • Makoto MINO, Shigeo NAKAGAWA, Mie IWAKOSHI, Kazuko MARUO, Toshiko HIME ...
    Article type: Article
    1980 Volume 54 Issue 3 Pages 95-103
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
    Using high performance liquid chromatography, α-tocopherol levels in the plasma and RBC were studied, as related to the hydrogen peroxide (H_2O_2) hemolysis, and then the normal range of them was estimated on the basis of H_2O_2 hemolysis. 1. Under our condition of the H_2O_2 hemolysis test, the level of less than 30% hemolysis was within normal range. 2. More than 30% of H_2O_2 hemolysis was accounted for 83.3% in the premature and neonatal age group, while the hemolysis all the cases of more than 1 month of age was less than 30%. 3. The distribution of plasma tocopherol levels in the group with less than 30% hemolysis was 300~1,100μg/dl, while that of RBC was 100~300/μg/dl packed cells. On the basis of 85 percentile of the group with more than 30% hemolysis, the lower limit of plasma α-tocopherol level was estimated as 450μg/dl. On the other hand, the lower limit of RBC α-tocopherol level was 125μg/dl packed cells, on the basis of 15 percentile of the group with less than 30% hemolysis, because of the finding that the distribution in α-tocopherol levels between both the groups were more clearly differed in the RBC than plasma. 4. The correlation with plasma α-tocopherol levels (X) and RBC levels (Y) extended in the range of Y=0.14X to Y=0.76X. 5. The mean values of the ratio of RBC α-tocopherol to plasma α-tocopherol were about 0.3 in each age group, where the ratios were widely distributed.
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  • Article type: Appendix
    1980 Volume 54 Issue 3 Pages 104-
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
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  • Article type: Appendix
    1980 Volume 54 Issue 3 Pages 105-107
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese]
    Article type: Article
    1980 Volume 54 Issue 3 Pages 108-
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese]
    Article type: Article
    1980 Volume 54 Issue 3 Pages 108-109
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
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  • [in Japanese], Robin C.Fraser, George A.Feigen
    Article type: Article
    1980 Volume 54 Issue 3 Pages 109-110
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
    Download PDF (208K)
  • [in Japanese]
    Article type: Article
    1980 Volume 54 Issue 3 Pages 111-112
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
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  • [in Japanese]
    Article type: Article
    1980 Volume 54 Issue 3 Pages 112-113
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
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  • [in Japanese]
    Article type: Article
    1980 Volume 54 Issue 3 Pages 113-114
    Published: March 25, 1980
    Released on J-STAGE: March 07, 2018
    JOURNAL FREE ACCESS
    Download PDF (286K)
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