VITAMINS

Online ISSN : 2424-080X
Print ISSN : 0006-386X

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Volume 48, Issue 4

Displaying 1-15 of 15 articles from this issue

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Studies on the Metabolism of Biotin by Microorganisms

Koichi OGATA, Yoshikazu IZUMI

Article type: Article
1974 Volume 48 Issue 4 Pages 159-178
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_159

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Studies on the biosynthesis and degradation of biotin-vitamers by microorganisms were reviewed and discussed. The main pathway of biotin biosynthesis by microorganisms is considered to be as follows : pimelic acid→pimelyl CoA→7-keto-8-aminopelargonic acid→7,8-diaminopelargonic acid→desthiobiotin→biotin. All the enzymes which are involved in the reactions from pimelic acid to desthiobiotin have been elucidated. The biosynthesis of biotin has been found to be controlled by biotin via enzyme repression. Biotin, desthiobiotin, and their analogs, are degraded by microorganisms to their corresponding catabolites, with acid side chains 2 or 4 carbon atoms shorter than their biotin-analogs, probably through a β-oxidation reaction. Biotin and desthiobiotin are also synthesized from their β-oxidation products.

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Influence of Penicillamine on Carbohydrate Metabolism

Miyako ABE

Article type: Article
1974 Volume 48 Issue 4 Pages 179-184
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_179

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Influence of DL-penicillamine (PeA) on the carbohydrate metabolism in liver of rat was investigated. Rats administered PeA were decreased in liver glycogen content and phosphorylase activity. Glucose-6-phosphatase which is known to be induced by cortisone was high in the liver of rats on PeA-containing diet. Rats treated with PeA were decreased in CO_2 generation from glucose by liver slices and in the activity of glucokinase which is known to be one of key enzymes participating in glycolysis and induced by insulin.

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A Seasonal Variation of Nutritional Status on Vitamins B_1 and C in Village Women

Tsuiko MANO, Yoko MATSUOKA

Article type: Article
1974 Volume 48 Issue 4 Pages 185-189
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_185

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The urinary excretion of vitamin B_1,vitamin C, and creatinine in 22 healthy village women was determined in different seasons, to evaluate their nutritional status with respect to the vitamins. The amount of the vitamins excreted in each of the urine was corrected to that corresponding to the standard creatinine concentration of urine according to the"Corrected Urinary Concentration Method". The corrected amounts were then compared with those of the vitamin intake on the previous day. A high correlation was found between vitamin C intake and the urinary excretion, while no significant correlation was observed with vitamin B_1. The urinary excretion of vitamin B_1 was much greater in the summer than in the spring and autumn, though its intake had been maintained at a rather constant level.

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Studies on Oral Absorption of Pyridoxal Phosphate by Means of Convulsant Effect of 2-Methyl-4-amino-5-hydroxymethylpyrimidine and Thiosemicarbazide in Mice

Shigeru MINAMI, Takeji TSUKAMOTO, Noboru SAKAGUCHI, Ritsuo NAKAMORI

Article type: Article
1974 Volume 48 Issue 4 Pages 191-194
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_191

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The absorption of orally administered pyridoxal phosphate (PALP), pyridoxal (PAL) and pyridoxine (PIN) was investigated by means of anticonvulsant effect against the 100% convulsant dose of 2-methyl-4-amino-5-hydroxymethylpyrimidine (OMP) and thiosemicarbazide (TSC) injected subcutaneously in mice. It was found that the absorption of PALP was better and more rapidly than that of PIN, but was much the same as PAL. The strongest anticonvulsant effect of PALP, PAL and PIN against the OMP convulsion were 3 to 4 times as high as TSC. From these results, the absorption of PALP are discussed.

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Studies on Growth of Rhizopus oligosporus and Folate Contents

Yukiko YAMAMOTO, Teijiro MIYAMOTO, Kiku MURATA

Article type: Article
1974 Volume 48 Issue 4 Pages 195-199
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_195

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The contents of folate compounds in tempeh were much higher than those produced by Rhizopus oligosporus in the soybean-potato medium. The cause of the fact was investigated. Any inhibitor for the folate production was not detected in potato extract or the boiled soybean juice. It was presumed that the main reason of higher concentration of folate compounds in tempeh will be a higher nutrients concentration together with the other suitable conditions for Rhizopus oligosporus in the tempeh fermentation.

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 202-203
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_202

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 203-204
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_203

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 204-
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_204_1

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 204-205
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_204_2

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 205-206
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_205

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 206-207
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_206

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 207-208
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_207

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 208-
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_208_1

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 208-209
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_208_2

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[title in Japanese]

[in Japanese]

Article type: Article
1974 Volume 48 Issue 4 Pages 209-210
Published: April 25, 1974
Released on J-STAGE: March 02, 2018

DOIhttps://doi.org/10.20632/vso.48.4_209

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