VITAMINS

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Print ISSN : 0006-386X

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Volume 58, Issue 7

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Comparison on the Clinical Data between the Two Kinds of Multivitamin Preparations(NK-041 and MVI)for Intravenous Hyperalimentation

Shohei OCOSHI, Masato IWASA, Masako TOMITA, Takatoshi SHIMOYAMA, Taket ...

Article type: Article
1984 Volume 58 Issue 7 Pages 253-266
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_253

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We studied the clinical data on the 2 kinds of multivitamin preparations, NK-041 (trial preparation) and MVI (commercially distributed preparation), for intravenous hyperalimentation (IVH) and compared one another. 1. Since MVI does not contain vitamin B_<12>, K, folic acid and biotin which were included in NK-041, the vitamins were administered by intravenous or intramusclur methods 2. During the administration of NK-041 and MVI, neither avitaminosis nor hypervitaminosis was observed and a side effect which was thought to be due to the preparations was observed in NK-041. 3. During the administration of NK-041 and MVI, clinical laboratory studies revealed that no abnormality due to the preparatins was observed in all the patients. 4. During the administration of NK-041, the blood levels of all the administered vitamins varied within the respective normal range or slightly higher levels. On the other hand, rather higher levels on vitamin B_1, B_6, and C and rather lower levels on vitamin E were observed by the administration of MVI. From all these results and observations, it is concluded that the NK-041 is useful as a multivitamin preparation for IVH with safety and good availavility.

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Effects of some drugs and thiamin deficiency on thiamin metabolism in rat brain in vivo

Toshio MATSUDA, Yasunori YABUSHITA, Tadashi DOI, Heitaroh IWATA

Article type: Article
1984 Volume 58 Issue 7 Pages 267-271
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_267

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Thiamin and its phosphate esters in rat brain were labeled with intraventricular injection of ^<35>S-thiamin. The effects of some drugs and thiamin deficiency on the distribution of the radioactive thiamin compounds in rat brain were examined. Reserpine (5 mg/kg, i.p., 19h) and methamphetamine (10 mg/kg, i.p., 1.5h) did not affect the distribution of radioactive thiamin and its phosphate esters. Pentobarbital Na (35 mg/kg, i.p., 1h) and ethanol (10 g/kg, p.o. or 3.5 g/kg, i.p., 1h) caused an increase of the ratio of thiamin phosphate esters. The lower ratio of TMP and TDP at 1h after the injection and the higher ratio of TTP at 3h were observed in cerebral cortex of thiamin-deficient rats.

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Article type: Article
1984 Volume 58 Issue 7 Pages 273-
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_273_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 273-274
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_273_2

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Article type: Article
1984 Volume 58 Issue 7 Pages 274-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_274_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 274-275
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_274_2

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Article type: Article
1984 Volume 58 Issue 7 Pages 275-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_275_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 275-276
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_275_2

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Article type: Article
1984 Volume 58 Issue 7 Pages 276-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_276_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 276-277
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_276_2

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Article type: Article
1984 Volume 58 Issue 7 Pages 277-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_277_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 277-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_277_2

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[title in Japanese]

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Article type: Article
1984 Volume 58 Issue 7 Pages 278-
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_278_1

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[title in Japanese]

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Article type: Article
1984 Volume 58 Issue 7 Pages 278-
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_278_2

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Article type: Article
1984 Volume 58 Issue 7 Pages 279-
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_279_1

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[title in Japanese]

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Article type: Article
1984 Volume 58 Issue 7 Pages 279-
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_279_2

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Article type: Article
1984 Volume 58 Issue 7 Pages 280-
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_280_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 280-281
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_280_2

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Article type: Article
1984 Volume 58 Issue 7 Pages 281-
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_281_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 281-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_281_2

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1984 Volume 58 Issue 7 Pages 282-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_282_1

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1984 Volume 58 Issue 7 Pages 282-283
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_282_2

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1984 Volume 58 Issue 7 Pages 283-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_283_1

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1984 Volume 58 Issue 7 Pages 283-284
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_283_2

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1984 Volume 58 Issue 7 Pages 284-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_284_1

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1984 Volume 58 Issue 7 Pages 284-285
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_284_2

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1984 Volume 58 Issue 7 Pages 285-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_285

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1984 Volume 58 Issue 7 Pages 286-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_286_1

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1984 Volume 58 Issue 7 Pages 286-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_286_2

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1984 Volume 58 Issue 7 Pages 286-287
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_286_3

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1984 Volume 58 Issue 7 Pages 287-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_287

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1984 Volume 58 Issue 7 Pages 288-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_288_1

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1984 Volume 58 Issue 7 Pages 288-289
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_288_2

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1984 Volume 58 Issue 7 Pages 289-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_289_1

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1984 Volume 58 Issue 7 Pages 289-290
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_289_2

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1984 Volume 58 Issue 7 Pages 290-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_290_1

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1984 Volume 58 Issue 7 Pages 290-291
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_290_2

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1984 Volume 58 Issue 7 Pages 291-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_291

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1984 Volume 58 Issue 7 Pages 292-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_292_1

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1984 Volume 58 Issue 7 Pages 292-293
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_292_2

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1984 Volume 58 Issue 7 Pages 293-
Published: July 25, 1984
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1984 Volume 58 Issue 7 Pages 293-294
Published: July 25, 1984
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1984 Volume 58 Issue 7 Pages 294-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_294_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 294-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_294_2

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1984 Volume 58 Issue 7 Pages 295-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_295_1

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1984 Volume 58 Issue 7 Pages 295-296
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_295_2

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1984 Volume 58 Issue 7 Pages 296-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_296_1

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1984 Volume 58 Issue 7 Pages 296-297
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_296_2

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1984 Volume 58 Issue 7 Pages 297-
Published: July 25, 1984
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DOIhttps://doi.org/10.20632/vso.58.7_297_1

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Article type: Article
1984 Volume 58 Issue 7 Pages 297-298
Published: July 25, 1984
Released on J-STAGE: March 10, 2018

DOIhttps://doi.org/10.20632/vso.58.7_297_2

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