VITAMINS
Online ISSN : 2424-080X
Print ISSN : 0006-386X
Volume 82, Issue 12
Displaying 1-8 of 8 articles from this issue
  • T. Nishiguchi, T. Kawamura, H. Yokoyama, K. Nagahashi, K. Hirai, M. Su ...
    Article type: Article
    2008 Volume 82 Issue 12 Pages 637-643
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
    The aim of present study is to investigate maternal PIVKA-PC and PIVKA-11 levels during early postpartum period and their correlation with estradiol (E_2) levels. Study subjects were 23 puerperal women without any medical complications or previous history of VTE (venous thromboembolism). Blood was sampled on the day 0, 1, and 2-3^<rd> postpartum day, and we measured protein C (PC) antigens & activity, PIVKA-PC, PIVKA-11, and E_2. The PIVKA-PC level in total PC was 10〜20% throughout the postpartum period. Compared to PIVKA-11 level, it's level was strikingly high. Moreover, significant difference in PIVKA-PC levels among delivery modes and a considerable correlation between PIVKA-PC and the declining ratio of E_2 (r=0.416) were observed. The reason for increased risk of VTE during early postpartum period remains unclear. The current study suggests that a high PIVKA-PC plays an important role in the mechanism of VTE.
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  • Wanjiao Zhang, Hisaaki Mihara, Tatsuo Kurihara, Nobuyoshi Esaki
    Article type: Article
    2008 Volume 82 Issue 12 Pages 645-650
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
    Three cysteine desulfurases-IscS, CsdA, and SufS-of Escherichia coli can transfer sulfur from L-cysteine to the C-terminal carboxylate of the smaller subunit of molybdopterin synthase to yield a thiocarboxylate group in a defined in vitro system for the generation of the dithiolene group of molybdopterin from precursor Z, which is an oxygen-sensitive tetrahydropyranopterin and the immediate precursor of molybdopterin in molybdenum cofactor biosynthesis. In this study, we report that an iscS-deletion strain of E. coli accumulates compound Z, a direct oxidation product of precursor Z, to the same extent as a ΔmoaD strain. In contrast, analysis of the content of compound Z in ΔsufS and ΔcsdA strains revealed no such accumulation. These findings suggest that IscS is the primary sulfur-donating enzyme for the generation of the thiocarboxylate of molybdopterin synthase in molybdopterin biosynthesis.
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  • Mariko Shin
    Article type: Article
    2008 Volume 82 Issue 12 Pages 651-654
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
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  • Shigenobu Kishino
    Article type: Article
    2008 Volume 82 Issue 12 Pages 655-657
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
    Article type: Article
    2008 Volume 82 Issue 12 Pages 658-659
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese]
    Article type: Article
    2008 Volume 82 Issue 12 Pages 659-660
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
    Download PDF (305K)
  • [in Japanese], [in Japanese]
    Article type: Article
    2008 Volume 82 Issue 12 Pages 660-
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
    Download PDF (156K)
  • Article type: Bibliography
    2008 Volume 82 Issue 12 Pages 661-665
    Published: December 25, 2008
    Released on J-STAGE: October 10, 2017
    JOURNAL FREE ACCESS
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