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Kiyoshi KIMURA
Article type: Article
1963 Volume 28 Issue 1 Pages
1-9
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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Kinzo SATO
Article type: Article
1963 Volume 28 Issue 1 Pages
10-19
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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Riboflavin in the blood is found mainly in the blood cells as esterified form. The content of esterified riboflavin in the blood cells is low in the majority of various diseases. Mass administration of free riboflavin results an increase of total riboflavin (mainly, the free type) in the blood up to 15μg/dl. One to two third of the orally administered dosis and three forth of intravenously adminstered dosis are excreted into the urine. Daily administration of 20 to 40 mg of ATP accelerates the esterification of riboflavin in the blood. Mass administration of thiamine or its derivatives (50-100mg per day) decreases the riboflavin content of blood within one to two weeks. However, addition of riboflavin as much as 10% of administered dosis of thiamine prevents the decrease of riboflavin content and increases the esterified form.
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Toshio KURODA
Article type: Article
1963 Volume 28 Issue 1 Pages
21-28
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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With the object to obtain the antagonists of vitamin B_6,following compounds were prepared ; pyridoxal-5-sulfate, pyridoxamine-5-sulfate, pyridoxine-5-sulfate, deoxypyridoxine-5-sulfate and pyridoxalmonoethylacetal-3-sulfate and so on. Several reactions between pyridoxine analogues and chlorosulfonic acid are described.
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Choten INAGAKI, Hiroyasu FUKUBA, Hiroko KAIBARA
Article type: Article
1963 Volume 28 Issue 1 Pages
29-32
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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The preventive actions for browning of food were compared with ascorbic acid and erythorbic acid. An experiment for the prevention of catechol solution by polyphenolase, it revealed that the both acids have almost equal potency in oxygen consumption and color change. For the browning of apple juice also, both acids have almost equal effect, measured by color and remaining acids.
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Choten INAGAKI, Kikuko FUJITANI
Article type: Article
1963 Volume 28 Issue 1 Pages
33-37
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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The preserving effects of ascorbic acid, erythorbic acid and their Na-salts for fresh fishes were compared by the estimation of trimethylamine and fluorescence of the extract. It was found that the both free acids were effecive for the preservation of the freshness of fish at same degree but the effects of their Na-salts were inferior to free acids.
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
37-
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
37-
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
JOURNAL
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
37-
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
JOURNAL
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Toshio NIIMURA, Shigeru INABA, Takao SUZUKI, Yoshikazu SAHASHI
Article type: Article
1963 Volume 28 Issue 1 Pages
38-40
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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Distribution of ^<35>S in the both biotin and sulfur deficient cells of Saccharomyces cerevisiae which have been incubated in the reaction mixture containing H_2S^*O_4 and glucose for 1 hour, was investigated by autoradiography. The countered relative amounts (cpm) of ^<35>S were 1054 in methionine, 340 in methionine sulfoxide, 120 in cysteic acid and 44 in cystine, and several other compounds showed less radioactivity. The incorporated ^<35>S was practically restricted in methionine and methionine sulfoxide, and was not found in the original sulfate form.
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Goichiro KATSUI, Seiji ISHIKAWA, Michiko SHIMIZU, Yukio NISHIMOTO
Article type: Article
1963 Volume 28 Issue 1 Pages
41-44
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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In this paper the detection method of fat-soluble vitamins and their related compounds by thin layer chromatography is described, using Kieselgel G and Aluminium oxid G as the chromatographic plates, and chloroform and benzene as the solvents for development. For the detection after chromatographic separation, 60% perchloric acid, 95% sulfuric acid, 65% nitric acid, antimony trichloride reagent and Emmerie-Engel reagent were used. 95% sulfuric acid proved to be universal detection reagent for all the fat-soluble vitamins separeted by this method. This method is advantageous because of being able to use sulfuric acid and perchloric acid as detection reagent, and because of taking shorter time than paper partion chromatography for the separation of fat-soluble vitamins.
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
44-
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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Hiromichi ONOZAKI, Toshiko TAKAKUWA
Article type: Article
1963 Volume 28 Issue 1 Pages
45-48
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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It has been demonstrated that the washed cells of A. gossypii incubated in maltose solution produce riboflavinylglucoside as well as riboflavin. Under the condition used, maximal production capacity was observed at 20℃ and pH 4.0,in citrate buffer. Biosynthesis was negligible in the presence of acetate.
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
48-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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Kazuya OKAMOTO
Article type: Article
1963 Volume 28 Issue 1 Pages
49-58
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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The aqueous solution of folic acid has a feeble white blue fluorescence which is markedly intensified by an addition 10^<-5> solution of KMnO_4 and distinctly decreases its intensity changing to yellowish green by an addition of HCl. Utilizing these characters as a histochemical detection method of folic acid in the organs of rats was established. The normal rats were orally and subcutaneously given by folic acid, and it was observed that the folic acid is absorbed from the intestine and stomach, and excreted from bile ducts, stomach and glandular cells of the intestine. The absorbed folic acid is mostly transported into liver cells. In the liver cells the vitamin is found abundantly in cytoplasm and scarcely in nucelei.
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Kazuya OKAMOTO
Article type: Article
1963 Volume 28 Issue 1 Pages
59-64
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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A histopathological study had been performed on the changes of digestive organs of experimental folic acid deficiency, using rats. The stomach revealed marked desquamation of epithelial cells and hemorrhagic erosion of the mucosa. In addition, the Auerbach's and Meisner's plexus showed marked degenerative changes of nervous cells. In liver, fatty degeneration and necrosis of liver cells were markedly encountered, especially in central zone of the lobules. Histochemical and resorption pictures using ultravaiolet microscopic observation revealed a marked decrease of nucleic acid and protein synthesis.
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Tadakatsu KATO, Shoichi SHIMIZU, Saburo FUKUI
Article type: Article
1963 Volume 28 Issue 1 Pages
65-71
Published: July 25, 1963
Released on J-STAGE: January 30, 2018
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A new yellow-orange substance was isolated from the cells of Propionibacterium shermanii grown in a medium containing cobinamide. The compound exhibited the coenzyme activity in the intramolecular oxidation-reduction system of Abeles・Lee. Its Km value was 6×10^<-6>M, 20 times as much as that of DBCC. It moved to cathode 1.5 times faster than cobinamide cyanide, hydroxo-cobalamin and DBCC at acidic pH in paperionophoresis, and gave the same spot as that of cobinamide cyanide after cyanide treatment. The shape of its absorption spectra in a neutral solution was analogous to that of DBCC except a difference in the wave length of the absorbancy maximum at 460mμ. The spectra was replaced by a spectra with double peaks at 350 and 500〜550mμ by exposure to light and changed to the spectra of cobinamide dicyanide by cyanide treatment. It exerted a little activity on E. coli mutant which was known to show a weak response to cobinamide and the derivatives. From these results, it would be concluded that the yellow orange substance was a coenzyme with cobinamide structure.
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
72-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
72-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
72-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
72-73
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
Article type: Article
1963 Volume 28 Issue 1 Pages
73-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
73-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
73-74
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
74-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
74-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
74-75
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
Article type: Article
1963 Volume 28 Issue 1 Pages
75-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
Article type: Article
1963 Volume 28 Issue 1 Pages
75-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
75-76
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
76-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
76-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
76-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
77-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
77-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
77-78
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
78-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
78-79
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
79-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
79-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
79-80
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
80-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
80-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
80-81
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
Article type: Article
1963 Volume 28 Issue 1 Pages
81-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
81-82
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
82-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
82-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
82-83
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
83-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1963 Volume 28 Issue 1 Pages
84-
Published: July 25, 1963
Released on J-STAGE: March 14, 2018
JOURNAL
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