VITAMINS

Online ISSN : 2424-080X
Print ISSN : 0006-386X

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Volume 54, Issue 4

Displaying 1-24 of 24 articles from this issue

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Stability of Vitamin B_6 to Light in Liquid Preparation

Nobuyasu MIZUNO, Emiko MRITA, Asami FUJIWARA

Article type: Article
1980 Volume 54 Issue 4 Pages 119-127
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_119

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In fact pyridoxine (PN) in a commercial internal solution (injection) was stable to light, but became unstable by dilution with distilled water or infusion fluid. PN, pyridoxamine, pyridoxamine 5'-phosphate, and pyridoxal 5'-phosphate were found to be relatively stable to light in the concentrated solutions (>25mM), but unstable in dilute solutions (<0.5mM). The results suggest that possible photodecomposition should be considered in handling dilute solution of vitamin B_6 for medical use. The photodecomposition of PN was slow in polyethylene container for the internal solution which had poor light transmittance, but was fast in polypropylene or glass container for the infusion fluid which showed high light transmittance.

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Ubiquinone 10 Content in the Liver and Serum in the Patients with Liver Diseases

Takumasa OKUYAMA, Shigeo MATSUO, Masahisa WADA

Article type: Article
1980 Volume 54 Issue 4 Pages 129-136
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_129

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Ubiquinone 10 (UQ_<10>) contents in liver and serum of patients with liver diseases were examined by using a high-performance liquid chromatography according to Abe and Katsui, and the following results were obtained. 1) UQ_<10> content of hepatic cells in 4 cases having more severe than intermediate degree of degeneration and necrosis was 92.4±22.4 μg/g wet weight, which was significantly lower than 130.2±14.5 μg/g wet weight in 5 cases having no liver injury. 2) Serum UQ_<10> Content in 23 patients with liver cirrhosis was 0.42±0.14 μg/ml, which was significantly lower than those in patients with other liver diseases (acute hepatitis: 0.76±0.33, chronic hepatitis: 0.74±0.26, hepatoma: 0.64±0.43) and healthy individuals (0.68±0.15). 3) Serum UQ_<10> content in 6 patients with acute hepatitis was low at the clinically extreme stage of illness and tended to increase toward the recovering stage. 4) A significant correlation was found between the serum total cholesterol level and the serum UQ_<10> content (r=0.443, n=58).

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 137-
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_137_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 137-138
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_137_2

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 138-
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_138_1

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

Article type: Article
1980 Volume 54 Issue 4 Pages 138-139
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_138_2

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 139-
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_139

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 141-
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_141

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 142-
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_142_1

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 142-144
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_142_2

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 144-
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_144_1

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[title in Japanese]

[in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 144-145
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_144_2

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 145-146
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_145

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 147-148
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_147

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 148-149
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_148

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 150-
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_150

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 151-152
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_151

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 152-153
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_152

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 153-154
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_153

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

Article type: Article
1980 Volume 54 Issue 4 Pages 154-155
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_154

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 155-156
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_155

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 157-158
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_157

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 158-159
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_158

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[title in Japanese]

[in Japanese]

Article type: Article
1980 Volume 54 Issue 4 Pages 159-161
Published: April 25, 1980
Released on J-STAGE: March 07, 2018

DOIhttps://doi.org/10.20632/vso.54.4_159

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