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Volume 69, Issue 3
Displaying 1-28 of 28 articles from this issue
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Keiko TAZUYA, Chie AZUMI, Kazuko YAMADA, Hiroshi KUMAOKAArticle type: Article
1995 Volume 69 Issue 3 Pages 167-173
Published: March 25, 1995
Released on J-STAGE: December 08, 2017
JOURNAL FREE ACCESSIn order to establish pyridoxine as a precursor of the pyrimidine moiety of thiamin in Saccharomyces cerevisiae, labeled pyridoxines, [^<15>N]-, [2'-^<13>C]- and [6-^<13>C]pyridoxines were chemically synthesized with alanine, formic acid and ethyl maleate via oxazole derivative. [^<15>N]-, [2'-^<13>C]- and [6-^<13>C]Pyridoxines were labeled with [^<15>N]-, [3-^<13>C]alanine and [^<13>C]formic acid, respectively. [5'-^2H_2]Pyridoxine was synthesized by the reduction of isopropylidene pyridoxic acid methyl ester with LiAID_4 followed by hydrolysis.View full abstractDownload PDF (533K) -
Akira MURATA, Il-Hwan LHO, Nobuyuki KITAMORI, Toshio KASHIHARA, Hirosh ...Article type: Article
1995 Volume 69 Issue 3 Pages 175-182
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSThe plasma concentration-time profile and urinary excretion of vitamin C after the oral administration of a single dose (1000 or 2000 mg) was examined using six healthy males (25-29 years) in a two-period crossover trial. The mean T_<max> (h) was 3 for both 1000 mg and 2000 mg. The mean C_<max> (mg/100 ml) was 1.13 for 1000 mg and 1.55 for 2000 mg (based on concentration above the initial value). The mean AUC (mg.g/100 ml, 0-24 h) was 11.16 for 1000 mg and 17.12 for 2000 mg. The plasma concentration-time profile could be simulated by a one-compartment model with first-order absorption. Ka (h^<-1>) were 0.31-0.33 and Ke (h^<-1>) were 0.31-0.33. V/F (liter) was 35 for 1000 mg and 49 for 2000 mg. The mean amount (mg, above the initial value) excreted in the 24-h urine was 269 for 1000 mg and 362 for 2000 mg. The percentage of the dose excreted was 27% for 1000 mg and 18% for 2000 mg.View full abstractDownload PDF (580K) -
Tomoko INUBUSHI, Michie SHIKIJI, Yasuko AOYAMA, Yasuo KISINO, Hisao KA ...Article type: Article
1995 Volume 69 Issue 3 Pages 183-189
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSThe changes of hepatic lysosomal cathepsins, alanine aminotransferase (AAT) activities and serum amino acids were studied on rat fed on high and low protein diets with or without B_6. The group fed on high protein diet without B_6 caused the marked suppression of growth and also in the pathological bad lie of hair with dermatosis, while these pathological syndromes were not observed in rats fed on low protein diet without B_6. The activities of cathepsins B, L, H and J in rats fed on high protein diet these cathepsin activities were not affected by B_6 deficiency. Therefore, the biosynthesis and also degradation of these cathepsins are not influenced by B_6 deficiency. Some amino acid levels in serum were increased by high protein diet intake and B_6 deficiency. The levels of glycine were significantly decreased in rat fed on high protein diet. The levels of aspartate and glycine were markedly elevated in the cases of B_6 deficiency and those of alanine and hydroxyproline were decreased in the cases of B_6 deficiency.View full abstractDownload PDF (609K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 191-198
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (718K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 199-206
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (767K) -
[in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 207-208
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (292K) -
[in Japanese], [in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 208-
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (181K) -
[in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 208-209
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (312K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...Article type: Article
1995 Volume 69 Issue 3 Pages 209-210
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (287K) -
[in Japanese], [in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 210-211
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (285K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 211-212
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (206K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 213-
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (144K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 213-214
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (274K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 214-215
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (326K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 216-
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (174K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 216-217
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (301K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 217-218
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (314K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 218-219
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (192K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 219-220
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (319K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 220-
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (174K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 221-222
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (308K) -
[in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 222-
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (188K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...Article type: Article
1995 Volume 69 Issue 3 Pages 222-223
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (256K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 225-226
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (267K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 226-228
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (410K) -
[in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 228-229
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (341K) -
[in Japanese], [in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 229-230
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (351K) -
[in Japanese]Article type: Article
1995 Volume 69 Issue 3 Pages 230-232
Published: March 25, 1995
Released on J-STAGE: March 17, 2018
JOURNAL FREE ACCESSDownload PDF (364K)
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