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Volume 62, Issue 11
Displaying 1-17 of 17 articles from this issue
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Tadashi TANABEArticle type: Article
1988 Volume 62 Issue 11 Pages 591-600
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSAcetyl-CoA carboxylase plays a central role in regulation of fatty acid biosynthesis. Animal acetyl-CoA carboxylase is composed of one kind of subunit with a molecular weight of 260,000, which contains a biotinyl prostheic group. Primary structure of chicken liver acetyl-CoA carboxylase was deduced from the nucleotide sequence of the CDNA. On the basis of the amino acid sequence localization of functional domains including biotin carboxylase, biotin carboxyl carrier protein and carboxyl transferase domains on the polypeptide chain is discussed. Proteolysis of acetyl-CoA carboxylase has been studied and cathepsin L and B were shown to be involved in the initial phase of the degradation of acetyl-CoA carboxylase in lysosomes. Palmitoyl-CoA binds tightly and reversively to acetyl-CoA carboxylase in an equimolar ratio to inhibit the enzyme, suggesting long-chain acyl-CoA is a specific and physiological inhibitor of the enzyme. Chicken liver acetyl-CoA carboxylase is regulated by phosphorylation. Possible phosphorylation sites of the enzyme are discussed.View full abstractDownload PDF (1160K) -
Etsuo NIKIArticle type: Article
1988 Volume 62 Issue 11 Pages 601-619
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSThe study on the action of vitamin E as an antioxidant has been summarized aiming specifically at discussing the mechanism and rate of radical scavenging, relative activities of α-, β-, γ-, and δ-tocopherol, behavior of vitamin E in the membranes, effect of phytyl side chain, synergistic inhibition of oxidation with vitamin C, interaction with iron, and suppression of oxidative hemolysis of erythrocytes.View full abstractDownload PDF (1764K) -
Mayumi MORISAKI, Keiko TAZUYA, Kazuko YAMADA, Hiroshi KUMAOKAArticle type: Article
1988 Volume 62 Issue 11 Pages 621-625
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSAlthough there have been many reports on the precursor of vitamin B_6, the biosynthetic pathway of B_6 has not yet been clearly established. We studied incorporation of L-[U-^<14>C]alanine, [2-^<14>C]pyruvate, [2-^<14>C]acetate, [^<14>C] formate and [2-^<14>C]glycerol into pyridoxine in Flavobacterium sp. No. 238-7. The respective radioactive carbon of alanine, pyruvate, acetate, formate and glycerol was incorporated into pyridoxine with high dilution. These findings suggest that the compounds tested are not the direct precursor and the biosynthetic route in Flavobacterium sp. No. 238-7 is different from that in Escherichia coli.View full abstractDownload PDF (552K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...Article type: Article
1988 Volume 62 Issue 11 Pages 627-
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (168K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...Article type: Article
1988 Volume 62 Issue 11 Pages 627-628
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (295K) -
[in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 628-
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (179K) -
[in Japanese], [in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 628-629
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (300K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...Article type: Article
1988 Volume 62 Issue 11 Pages 629-630
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (313K) -
[in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 630-631
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (268K) -
[in Japanese], [in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 631-
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (127K) -
[in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 633-
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (161K) -
[in Japanese], [in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 634-
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (189K) -
[in Japanese], [in Japanese], [in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 634-635
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (319K) -
[in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 635-636
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (201K) -
[in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 637-639
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (324K) -
[in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 639-640
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (295K) -
[in Japanese]Article type: Article
1988 Volume 62 Issue 11 Pages 640-641
Published: November 25, 1988
Released on J-STAGE: March 16, 2018
JOURNAL FREE ACCESSDownload PDF (280K)
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