The characteristic features of allergic diseases in common are discussed. Allergic disorders exhibit considerable hereditary influence but our knowledge of the inherited allergic constitution is yet incomplete. It is assumed than (1) sensitized antibodies are easily produced, (2) there is hypersensitivity to chemical mediators and (3) the ability to inhibit the action of chemical inhibitors is absent, and these peculiarities probably result in the recurring manifestations of allergic symptoms. The processes by which the allergic symptoms are produced are discussed in relation to the above-mentioned peculiarities as well as to infection. Lastly, various problems concerning therapeutic measures are discussed.
With 46 cases consisting of 17 of Ménière's disease and atypical Ménière's disease, as cases of vertigo for the main complaint, 9 of the perceptive tinnitus, as cases of tinnitus for the main complaint, and 20 of the abnormal sensation in the laryngeal region, (8 males and 38 females), I have studied 44 cases regarding the co-efficients of the blood pressure and the heart rate, and 24 cases, regarding the Imidalin Cutaneous Reaction. In this way I observed each patient's condition of the function of the autonomic nervous system, and I placed my judgement on the function of it for each individual patient as “Unstable”, in case I found one of the tests should prove unstable. When I observed through the co-efficient of the variation both of the blood pressure and the heart rate, there were 8 cases who complained of vertigo, out of 16 cases of Ménière's disease and atypical Ménière's disease, 3 cases who complained of the perceptive tinnitus, out of 9 cases, and one case proved to be autonomic imbalance, out of 19 cases of the abnormal sensation in the laryngeal region. When I observed- through the Imidalin Cutaneous Reaction, according to the classification of Messrs. Kawakubo and Yamamoto, 7 cases out of 8 who complained of vertigo, all of2 cases who complained of the perceptive tinnitus, and all of 14 cases who complained of the abnormal sensation in the laryngeal region, showed figures over 210 mm2, and the mean value of 14 cases of the abnormal sensation in the laryngeal region was 715 mm2, which means that the Imidalin Cutaneous Reaction has shown more remarkable results than the co-efficients of the variation of the blood pressure and the heart rate.
Although observance of double cancer in our field in not necessarily frequent, occasianal cases have been reported in recent years. We have recently encountered 3 clinical cases of double cancer involving the bladder and the maxilla in one case and the larynx in2 cases. These cases are presented together with a statistical observation of such occurrences. The types of cancer in our cases consisted of epithelioid carcinoma of the maxillary sinus and papillary transitional epithelial carcinoma of the bladder in a 69-year-old man, squamous cell carcinoma of the larynx and primary adenocarcinoma of the stomach in a 60-year-old woman, and squamous cell carcinoma of the larynx and adenocarcinoma of the stomach in a 66-year-old man.
The usual method of paracentesis of the tympanic membrane, using the left hand to hold the needle steady and the right hand to advance the syringe and to aspirate, obscures the view of the tympanic membrane. When a syringe with spring attachment is used, one is apt to experience difficulty in holding the syringe steady throughout the procedure. To overcome these disadvantages, the syringe was replaced by a glass bubble connector, to one end of which an angled needle was connected. The other end was attached to the suction outlet of the ENT unit. These modifications resulted in reducing the weight of the apparatus and in simplifying the procedure. An opening was made at the top of the glass bubble to prevent abrupt negative pressure in the tympanic cavity and to control the suction. By gripping the apparatus as one would a pen, puncture of the tympanic membrane is easily performed while directly visualizing the surface of the tympanic membrane.