For the early treatment of the perceptive deafness caused by otomicrosurgery, significance of early detection of the change of bone conduction threshold has been discussed based on selfexperienced cases.
Avairable literatures were referred for the incidence pathology and etiology of the condition. Furthermore, importance of meticulous surgery with skillful hands has been stressed for the prevention of postoperative deafness.

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Three cases of rhinogenous meningitis were reported.
The first case, 10 year-old boy, was due to supprative focus on the apex of the nose.
The second case, 12 year-old girl, had its origin in acute pan-sinusitis.
The third case, 26 year-old man, was follawed by Luc-Caldwell's operation.
These cases were successfully treated with several kinds of antibiotics. Authors discussed About etiology, application of the suitable antibiotics, importance of lumbar puncture and surgical treatment against original focus.

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A rare case of large mixid tumor which encountered in the nose and paranasal sinus of a 62-year old male is reported.
The large tumor which occupied left antrum and left nasal cavity causing marked swelling of the left cheek was successfully removed “en block” with Weber's incision and followed by tele-cobalt therapy.
Diagnosis of mixed tumor with malignant character was confirmed by microscopic examination, while no evidence is avairable so far to indicate recurrence of the tumor at 11 months postoperatively.

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This paper reports on treatments with three anticancer drugs (Carzinophilin, Toyomycin and Endoxan), performed on patients with head and neck malignancies.
The treated patients numbered 22 cases (8 cases of maxillary cancer, 6 cases of laryngeal cancer, 3 cases of lingual cancer, 2 cases of epipharyngeal sarcoma and 3 cases in other regions), and administration of the drugs was made intravenously in almost all cases.
A few patients (4 cases) were treated with anticancer drug only, but majority were given it in combination with radiotherapy and/or radical operation.
The efficacy was objectively visible in 1 of 4 cases treated with carzinophilin, in 2 of 7 cases treated with Toyomycin. Of 11 cases given Endoxan, 1 case of relapsing laryngeal cancer showed reduction in tumor size, and 6 cases who were given Endoxan after operation did not show relapse during a period from 5 months to 1 year and 2 months observation.
It was of interest that all these cases of favorable response did not receive the anticancer drug alone, but received it in combination with rodiotherapy with or without operation.
As for side effect on the hemopoietic organ, Carzinophilin produced it in 75%, Toyomycin in 0%, and Endoxan in 27%.

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