Like nebulization therapy for the nasal and paranasal sinuses, laryngeal nebulization therapy is an important and frequently used means of treating otorhinolaryngological disease. Last year, at the 18th meeting of this society, headed by Prof. Ginichiro Ichikawa of Juntendo University, I served as the chairman of the symposium entitled “Problems regarding laryngeal nebulization therapy”. Presentations made during that symposium was published in O.R.L. Tokyo 38 Supplement 2, 1995. Today's symposium focused on confirming basic data regarding effective methods of laryngeal nebulization therapy and exchanging clinical data which indicate effective methods of nebulization therapy, effective drugs for nebulization therapy and cases responding well to this therapy, with emphasis laid on inflammatory laryngeal disease. The first four presentations appertain to the basics of laryngeal nebulization therapy. First, Dr. Suzuki will make a presentation on the kinetics of bacterial flora in the larynx. Dr. Kumazawa will then speak about deposition of aerosols in the larynx following nebulization therapy. Third, Dr. Shimizu will report on levels of inhaled drugs in blood and airway mucosa as well as histological changes in the airway mucosa following inhalation of drugs using a nebulizer. Dr. Mori will then speak about the effects of changes in relative humidity, osmotic pressure and pH on the airway mucosa. The first presentation on the clinical aspects of nebulization therapy will be made by Dr. Muta, who will present clinical results of laryngeal nebulization application of antimicrobial agents in the treatment of acute inflammatory disease and wounds which is made by phonosurgical operations. Dr. Hyo and Dr. Ogawa will then report on attempts to objectively evaluate the redness of the laryngeal mucosa using digital video images. Finally, Dr. Matsune will report on attempts to develop objective means of assessing lesions of the laryngeal mucosa, using a rigid laryngoscope, stroboscope, TV camera, electronic endoscope. I hope this symposium will serve as a milestone regarding basic and clinical aspects of effective laryngeal nebulization therapy for inflammatory disease.